Inhibition of in Vitro and in Vivo HIV Replication by a Distamycin Analogue That Interferes with Chemokine Receptor Function: A Candidate for Chemotherapeutic and Microbicidal Application
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References (30)
Statistical Learning by 8-Month-Old Infants
1996 • 5,373 citations
HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor
1996 • 4,184 citations
Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural Gene
1996 • 2,502 citations
The β-Chemokine Receptors CCR3 and CCR5 Facilitate Infection by Primary HIV-1 Isolates
1996 • 2,326 citations
The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry
1996 • 1,973 citations
A Dual-Tropic Primary HIV-1 Isolate That Uses Fusin and the β-Chemokine Receptors CKR-5, CKR-3, and CKR-2b as Fusion Cofactors
1996 • 1,868 citations
The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1
1996 • 1,678 citations
CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5
1996 • 1,058 citations
Requirement of p27 Kip1 for Restriction Point Control of the Fibroblast Cell Cycle
1996 • 683 citations
Potent Inhibition of HIV-1 Infectivity in Macrophages and Lymphocytes by a Novel CCR5 Antagonist
1997 • 622 citations
HIV Coreceptor Downregulation as Antiviral Principle: SDF-1α–dependent Internalization of the Chemokine Receptor CXCR4 Contributes to Inhibition of HIV Replication
1997 • 564 citations
Inhibition of T-tropic HIV Strains by Selective Antagonization of the Chemokine Receptor CXCR4
1997 • 556 citations
CD40 Ligand-Dependent T Cell Activation: Requirement of B7-CD28 Signaling Through CD40
1996 • 421 citations
A Small Molecule CXCR4 Inhibitor that Blocks T Cell Line–tropic HIV-1 Infection
1997 • 391 citations
A Small-molecule Inhibitor Directed against the Chemokine Receptor CXCR4 Prevents its Use as an HIV-1 Coreceptor
1997 • 335 citations
Chemokine receptors: Structure, function and role in microbial pathogenesis
1996 • 329 citations
Multiple Extracellular Elements of CCR5 and HIV-1 Entry: Dissociation from Response to Chemokines
1996 • 314 citations
Identification of a Chemokine Receptor Encoded by Human Cytomegalovirus as a Cofactor for HIV-1 Entry
1997 • 309 citations
Chemokines and HIV–1 second receptors
1996 • 304 citations
Regions in β-Chemokine Receptors CCR5 and CCR2b That Determine HIV-1 Cofactor Specificity
1996 • 298 citations
HIV-1 Coreceptor Activity of CCR5 and Its Inhibition by Chemokines: Independence from G Protein Signaling and Importance of Coreceptor Downmodulation
1997 • 214 citations
HIV-1 Entry and Macrophage Inflammatory Protein-1β-mediated Signaling Are Independent Functions of the Chemokine Receptor CCR5
1997 • 183 citations
Molecular uncoupling of C-C chemokine receptor 5-induced chemotaxis and signal transduction from HIV-1 coreceptor activity
1997 • 176 citations
Serum amyloid A induces calcium mobilization and chemotaxis of human monocytes by activating a pertussis toxin-sensitive signaling pathway.
1995 • 146 citations
Activation of the G Protein Gq/11 Through Tyrosine Phosphorylation of the α Subunit
1997 • 134 citations
Polymorphisms in the CCR5 genes of African green monkeys and mice implicate specific amino acids in infections by simian and human immunodeficiency viruses
1997 • 83 citations
Receptor-mediated Endocytosis of CC-chemokines
1997 • 80 citations
Novel sulfonated and phosphonated analogs of distamycin which inhibit the replication of HIV
1995 • 43 citations
In vivo drug screening applications of HIV-infected cells cultivated within hollow fibers in two physiologic compartments of mice
1995 • 24 citations
Advances in Pharmacology. Volume 4.
1967 • 1 citations