Astrocytes are required for the oscillatory activity in cultured hippocampal neurons

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Knockout of Glutamate Transporters Reveals a Major Role for Astroglial Transport in Excitotoxicity and Clearance of Glutamate

1996 • 2,470 citations

Glutamate-mediated astrocyte–neuron signalling

1994 • 1,688 citations

Localization of neuronal and glial glutamate transporters

1994 • 1,668 citations

Primary structure and functional characterization of a high-affinity glutamate transporter

1992 • 1,319 citations

Prostaglandins stimulate calcium-dependent glutamate release in astrocytes

1998 • 1,138 citations

Rat hippocampal neurons in dispersed cell culture

1977 • 1,106 citations

Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex

1994 • 988 citations

Metabolic coupling between glia and neurons

1996 • 985 citations

Glutamate transporters in glial plasma membranes: Highly differentiated localizations revealed by quantitative ultrastructural immunocytochemistry

1995 • 821 citations

GABAA, NMDA and AMPA receptors: a developmentally regulated 'ménage à trois'

1997 • 807 citations

Synaptic Efficacy Enhanced by Glial Cells in Vitro

1997 • 771 citations

Growth and cultivation of dissociated neurons and glial cells from embryonic chick, rat and human brain in flask cultures.

1972 • 760 citations

THE STRUCTURAL SPECIFICITY OF THE HIGH AFFINITY UPTAKE OF <scp>l</scp>‐GLUTAMATE AND <scp>l</scp>‐ASPARTATE BY RAT BRAIN SLICES

1972 • 694 citations

Neuronal Polarity

1994 • 658 citations

Glutamate receptor desensitization and its role in synaptic transmission

1989 • 459 citations

Stoichiometry of the Glial Glutamate Transporter GLT-1 Expressed Inducibly in a Chinese Hamster Ovary Cell Line Selected for Low Endogenous Na⁺-Dependent Glutamate Uptake

1998 • 454 citations

Greenfield's Neuropathology

1993 • 445 citations

Chemical transmission between rat sympathetic neurons and cardiac myocytes developing in microcultures: evidence for cholinergic, adrenergic, and dual-function neurons.

1976 • 429 citations

Intracellular Ca2+ Fluctuations Modulate the Rate of Neuronal Migration

1996 • 402 citations

Prolonged presence of glutamate during excitatory synaptic transmission to cerebellar Purkinje cells

1994 • 361 citations

An electron microscopic study of the development of axons and dendrites by hippocampal neurons in culture. I. Cells which develop without intercellular contacts

1984 • 358 citations

Glial contributions to excitatory neurotransmission in cultured hippocampal cells

1994 • 349 citations

Developmental profile and synaptic origin of early network oscillations in the CA1 region of rat neonatal hippocampus

1998 • 348 citations

Block of glutamate transporters potentiates postsynaptic excitation

1994 • 345 citations

Conformationally defined neurotransmitter analogs. Selective inhibition of glutamate uptake by one pyrrolidine-2,4-dicarboxylate diastereomer

1991 • 303 citations

Functions of the two glutamate transporters GLAST and GLT-1 in the retina

1998 • 240 citations

Spontaneous synchronous synaptic calcium transients in cultured cortical neurons

1992 • 177 citations

Glutamate uptake from the synaptic cleft does not shape the decay of the non-NMDA component of the synaptic current

1993 • 170 citations

Characterization of the glutamate transporter in retinal cones of the tiger salamander

1993 • 162 citations

New views on synapse—glia interactions

1996 • 157 citations

Seizure-like activity and cellular damage in rat hippocampal neurons in cell culture

1989 • 156 citations

Epileptiform activity in microcultures containing small numbers of hippocampal neurons

1990 • 151 citations

A Regulated Secretory Pathway in Cultured Hippocampal Astrocytes

1999 • 150 citations

Breaking the Code: Regulation of Neuronal Differentiation by Spontaneous Calcium Transients

1997 • 147 citations

Alterations in Glutamate Transporter Protein Levels in Kindling‐Induced Epilepsy

1997 • 137 citations

Prolonged activation of the N -methyl- <scp>d</scp> -aspartate receptor–Ca ²⁺ transduction pathway causes spontaneous recurrent epileptiform discharges in hippocampal neurons in culture

1998 • 124 citations

Astrocytes in glutamate neurotransmission

1995 • 121 citations

Rapid communication between neurons and astrocytes in primary cortical cultures

1993 • 118 citations

Synaptic and intrinsic mechanisms shape synchronous oscillations in hippocampal neurons in culture

1999 • 118 citations

Epileptiform activity in microcultures containing one excitatory hippocampal neuron

1991 • 101 citations

The role of glial cells in synaptic function

1999 • 100 citations

Non‐synaptic Localization of the Glutamate Transporter EAACI in Cultured Hippocampal Neurons

1997 • 93 citations

Presynaptic influence on the time course of fast excitatory synaptic currents in cultured hippocampal cells

1995 • 93 citations

Modulation of excitatory synaptic transmission by low concentrations of glutamate in cultured rat hippocampal neurons.

1996 • 72 citations

Quantification of excitatory amino acid uptake at intact glutamatergic synapses by immunocytochemistry of exogenous D-aspartate

1995 • 62 citations

Synaptogenesis in hippocampal cultures

1999 • 61 citations

[Ca2+]i imaging in PC12 cells: multiple response patterns to receptor activation reveal new aspects of transmembrane signaling.

1991 • 56 citations

Endogenous bursts underlie seizurelike activity in solitary excitatory hippocampal neurons in microcultures

1994 • 55 citations

Mechanisms for Synchronous Calcium Oscillations in Cultured Rat Cerebellar Neurons

1996 • 47 citations

Emergence of order in visual system development

1996 • 46 citations

Intercellular signaling in neuronal-glial networks

1995 • 46 citations

Astrocytic contribution to functioning synapse formation estimated by spontaneous neuronal intracellular Ca 2+ oscillations

1994 • 42 citations

Mechanisms of synaptogenesis in hippocampal neurons in primary culture

1995 • 32 citations

Synchronous calcium oscillations in cerebellar granule cells in culture mediated by NMDA receptors

1993 • 28 citations

Coupling of Glutamate Uptake and Degradation in Transmitter Clearance: Anatomical Evidence

1997 • 10 citations

Paroxysmal long‐lasting depolarizations in cultured hippocampal neurons are generated by activation of NMDA and non‐NMDA receptors

1993 • 4 citations