Repacking protein interiors

Some Factors in the Interpretation of Protein Denaturation

1959 • 4,817 citations

AREAS, VOLUMES, PACKING, AND PROTEIN STRUCTURE

1977 • 2,631 citations

The hydrophobic effect

1980 • 1,922 citations

Tertiary templates for proteins

1987 • 1,485 citations

The Solubility of Amino Acids and Two Glycine Peptides in Aqueous Ethanol and Dioxane Solutions

1971 • 1,417 citations

Principles of protein structure

1980 • 1,094 citations

Principles of Protein Structure

1979 • 1,090 citations

The interpretation of protein structures: Total volume, group volume distributions and packing density

1974 • 906 citations

Hydrophobic bonding and accessible surface area in proteins

1974 • 887 citations

Structural invariants in protein folding

1975 • 865 citations

How different amino acid sequences determine similar protein structures: The structure and evolutionary dynamics of the globins

1980 • 697 citations

The Stability of Globular Protein

1975 • 648 citations

PRINCIPLES THAT DETERMINE THE STRUCTURE OF PROTEINS

1984 • 645 citations

Comparing the polarities of the amino acids: side-chain distribution coefficients between the vapor phase, cyclohexane, 1-octanol, and neutral aqueous solution

1988 • 595 citations

Characterization of a Helical Protein Designed from First Principles

1988 • 533 citations

Protein Design, a Minimalist Approach

1989 • 465 citations

Contribution of hydrophobic interactions to protein stability

1988 • 413 citations

Alternative packing arrangements in the hydrophobic core of λrepresser

1989 • 375 citations

Hydrophobic stabilization in T4 lysozyme determined directly by multiple substitutions of Ile 3

1988 • 375 citations

Energetics of complementary side chain packing in a protein hydrophobic core

1989 • 346 citations

Combinatorial Cassette Mutagenesis as a Probe of the Informational Content of Protein Sequences

1988 • 326 citations

Design of Peptides and Proteins

1988 • 296 citations

Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding

1989 • 203 citations

Influence of Interior Packing and Hydrophobicity on the Stability of a Protein

1989 • 173 citations

Structural plasticity broadens the specificity of an engineered protease

1989 • 165 citations

Harnessing disulfide bonds using protein engineering

1987 • 116 citations

Effects of multiple replacements at a single position on the folding and stability of dihydrofolate reductase from Escherichia coli

1989 • 70 citations

Stability of protein conformation: Internal packing and enthalpy of fusion of model compounds

1977 • 27 citations