Monoclonal Antibodies to Human Epidermal Filaggrin, Some Not Recognizing Profilaggrin

Continuous cultures of fused cells secreting antibody of predefined specificity

1975 • 17,037 citations

MOLECULAR AND CELLULAR BIOLOGY OF INTERMEDIATE FILAMENTS

1988 • 1,395 citations

The Antigenic Structure of Proteins: A Reappraisal

1984 • 957 citations

Immunolocalization of keratin polypeptides in human epidermis using monoclonal antibodies

1982 • 777 citations

Stratum Corneum Moisturization at the Molecular Level

1994 • 467 citations

Use of monospecific antisera and cRNA probes to localize the major changes in keratin expression during normal and abnormal epidermal differentiation.

1988 • 359 citations

Ichthyosis Vulgaris: Identification of a Defect in Synthesis of Filaggrin Correlated with an Absence of Keratohyaline Granules

1985 • 288 citations

Assembly of stratum corneum basic protein and keratin filaments in macrofibrils

1978 • 282 citations

The cytokeratin filament-aggregating protein filaggrin is the target of the so-called "antikeratin antibodies," autoantibodies specific for rheumatoid arthritis.

1993 • 259 citations

Protein composition of cornified cell envelopes of epidermal keratinocytes

1994 • 246 citations

Histidine-rich protein of the keratohyalin granules

1982 • 243 citations

Histidine-rich proteins (filaggrins): Structural and functional heterogeneity during epidermal differentiation

1983 • 240 citations

Organization, structure, and polymorphisms of the human profilaggrin gene

1990 • 186 citations

Characterization of the human epidermal profilaggrin gene. Genomic organization and identification of an S-100-like calcium binding domain at the amino terminus.

1992 • 169 citations

Identification of Late Differentiation Antigens of Human Cornified Epithelia, Expressed in Re-Organized Desmosomes and Bound to Cross-Linked Envelope

1991 • 165 citations

Profilaggrin, a High-Molecular-Weight Precursor of Filaggrin in Human Epidermis and Cultured Keratinocytes

1985 • 130 citations

Characterization of a cDNA clone encoding human filaggrin and localization of the gene to chromosome region 1q21.

1989 • 124 citations

Profilaggrin is a Major Epidermal Calcium-Binding Protein

1993 • 123 citations

The characterization of human epidermal filaggrin

1983 • 120 citations

Interaction of filaggrin with keratin filaments during advanced stages of normal human epidermal differentiation and in Ichthyosis vulgaris

1991 • 118 citations

Molecular biology of the skin : the keratinocyte

1993 • 117 citations

Profilaggrin is a major epidermal calcium-binding protein.

1993 • 107 citations

The Mechanism of Interaction of Filaggrin with Intermediate Filaments

1993 • 100 citations

Characterization of Two Monoclonal Antibodies to Human Epidermal Keratohyalin: Reactivity With Filaggrin and Related Proteins

1987 • 88 citations

Identification of Proteolytic Cleavage Sites in the Conversion of Profilaggrin to Filaggrin in Mammalian Epidermis

1989 • 80 citations

Immunocytochemical evidence for a possible role of cross-linked keratinocyte envelopes in stratum corneum cohesion.

1991 • 79 citations

Evidence for filaggrin as a component of the cell envelope of the newborn rat

1988 • 52 citations

Natural IgM and IgG Autoantibodies to Epidermal Keratins in Normal Human Sera. I: ELISA-Titration, Immunofluorescence Study

1987 • 46 citations

The Occurrence of Profilaggrin and Its Processing in Cultured Keratinocytes

1985 • 35 citations

Phenotypic Expression and Processing of Filaggrin in Epidermal Differentiation

1993 • 26 citations

Monoclonal anti thymic cell antibodies detecting epidermal cells.

1984 • 25 citations

Limited Proteolysis of High Molecular Weight Histidine-Rich Protein of Rat Epidermis by Epidermal Proteinases

1988 • 19 citations

The rheumatoid arthritis-associated autoantibodies to filaggrin label the fibrous matrix of the cornified cells but not the profilaggrin-containing keratohyalin granules in human epidermis

1995 • 18 citations

Keratohyalin granules are heterogeneous in ridged and non-ridged human skin: evidence from anti-filaggrin immunogold labelling of normal skin and skin of autosomal dominant ichthyosis vulgaris patients

1991 • 17 citations