Surface modification of proteins activation of monomethoxy-polyethylene glycols by phenylchloroformates and modification of ribonuclease and superoxide dismutase

Superoxide Dismutase

1969 • 12,578 citations

Alteration of immunological properties of bovine serum albumin by covalent attachment of polyethylene glycol.

1977 • 1,311 citations

Effect of covalent attachment of polyethylene glycol on immunogenicity and circulating life of bovine liver catalase.

1977 • 1,239 citations

An improved 2,4,6-trinitrobenzenesulfonic acid method for the determination of amines

1975 • 748 citations

A new procedure for the synthesis of polyethylene glycol-protein adducts; Effects on function, receptor recognition, and clearance of superoxide dismutase, lactoferrin, and α2-macroglobulin

1983 • 205 citations

A method for the estimation of polyethylene glycol in plasma protein fractions

1980 • 156 citations

Functionalization of poly(ethylene glycol) and monomethoxy‐poly(ethylene glycol)

1981 • 155 citations

Soluble dextran-hemoglobin complex as a potential blood substitute.

1976 • 117 citations

Preparation of a polyethylene glycol: superoxide dismutase adduct, and an examination of its blood circulation life and anti-inflammatory activity.

1980 • 85 citations

Anti-inflammatory and pharmacokinetic properties of superoxide dismutase derivatized with polyethylene glycol via active esters

1983 • 67 citations

Enhanced anti-inflammatory effect and reduced immunogenicity of bovine liver superoxide dismutase by conjugation with homologous albumin

1980 • 64 citations

Pharmacokinetic properties of polyethylene glycol derivatized superoxide dismutase

1982 • 61 citations

Stabilization of Human beta-D-N-Acetylhexosaminidase A towards Proteolytic Inactivation by Coupling It to Poly(N-vinylpyrrolidone)

1977 • 35 citations

Modification of amino groups in porcine pancreatic elastase with polyethylene glycol in relation to binding ability towards anti-serum and to enzymic activity

1983 • 24 citations

Synthesis and spectroscopic characterization of insulin derivatives containing one or two poly(ethylene oxide) chains at specific positions

1983 • 13 citations