Age-dependent decline in human brain dopamine D1 and D2 receptors

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Analysis of radioligand binding experiments

1985 • 1,247 citations

Effects of Age on Dopamine and Serotonin Receptors Measured by Positron Tomography in the Living Human Brain

1984 • 701 citations

Aging and Extrapyramidal Function

1977 • 650 citations

Time course of nigrostriatal degeneration in parkinson's disease

1976 • 561 citations

Human brain dopamine receptors in children and aging adults

1987 • 404 citations

Studies on the pharmacological properties of dopamine receptors in various areas of the central nervous system.

1978 • 260 citations

Neurotransmitter receptor alterations in Parkinson's disease

1977 • 251 citations

Age‐Correlated Loss of Dopaminergic Binding Sites in Human Basal Ganglia

1982 • 212 citations

Dopamine Receptor Parameters Detected by [³H]Spiperone Depend on Tissue Concentration: Analysis and Examples

1984 • 173 citations

Localization of Nigral Dopamine-Sensitive Adenylate Cyclase on Neurons Originating from the Corpus Striatum

1977 • 147 citations

Dopamine receptor subtype imbalance in schizophrenia

1987 • 141 citations

Serotonin-2 binding sites in human frontal cortex and hippocampus. Selective loss of S-2A sites with age

1984 • 139 citations

Muscarinic and dopaminergic receptors in the aging human brain

1987 • 130 citations

Loss of Striatal [⁷⁶Br]Bromospiperone Binding Sites Demonstrated by Positron Tomography in Progressive Supranuclear Palsy

1986 • 112 citations

Divergent changes in D-1 and D-2 dopamine binding sites in human brain during aging

1987 • 82 citations

Dopaminergic Changes in the Basal Ganglia A Generalized Phenomenon of Aging in Mammalsa

1988 • 76 citations

Prevalence of abnormal involuntary movements (?spontaneous dyskinesias?) in the normal elderly

1982 • 66 citations

D-1 dopamine receptors labelled with 3H-SCH 23390: Decrease in the striatum of aged rats

1987 • 56 citations

NEUROLOGICAL SIGNS IN A NORMAL POPULATION

1972 • 52 citations

[³H]SCH 23390 Binding to Human Putamen D‐1 Dopamine Receptors: Stereochemical and Structure‐Affinity Relationships Among l‐Phenyl‐1H‐3‐Benzazepine Derivatives as a Guide to D‐l Receptor Topography

1987 • 34 citations

Dopamine receptors in Parkinson's disease

1988 • 20 citations

Basal Ganglia Dopamine Receptor Autoradiography and Age‐related Movement Disordersa

1988 • 19 citations

Parallel Decrease in the Density of Dopamine D₁ and D₂ Receptors in Corpus Striatum of Rats from 3 to 25 Months of Age

1989 • 19 citations

Neurologic Signs in Uncomplicated Aging (Senescence)

1981 • 17 citations