The active form of the steroidogenic acute regulatory protein, StAR, appears to be a molten globule

Principles that Govern the Folding of Protein Chains

1973 • 6,771 citations

Calculation of protein extinction coefficients from amino acid sequence data

1989 • 5,198 citations

Empirical Predictions of Protein Conformation

1978 • 3,167 citations

[14]Determination and analysis of urea and guanidine hydrochloride denaturation curves

1986 • 2,265 citations

The molten globule state as a clue for understanding the folding and cooperativity of globular‐protein structure

1989 • 1,446 citations

Molecular Biology of Steroid Hormone Synthesis*

1988 • 1,387 citations

In-gel digestion of proteins for internal sequence analysis after one- or two-dimensional gel electrophoresis

1992 • 1,259 citations

Molten Globule and Protein Folding

1995 • 1,203 citations

The purification, cloning, and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR).

1994 • 1,140 citations

Role of Steroidogenic Acute Regulatory Protein in Adrenal and Gonadal Steroidogenesis

1995 • 1,019 citations

Regulation of the Acute Production of Steroids in Steroidogenic Cells*

1996 • 995 citations

Protein secondary structure and circular dichroism: A practical guide

1990 • 926 citations

Secondary Structure of Proteins Through Circular Dichroism Spectroscopy

1988 • 537 citations

Improved prediction of protein secondary structure by use of sequence profiles and neural networks.

1993 • 525 citations

A 'molten-globule' membrane-insertion intermediate of the pore-forming domain of colicin A

1991 • 416 citations

Human steroidogenic acute regulatory protein: functional activity in COS-1 cells, tissue-specific expression, and mapping of the structural gene to 8p11.2 and a pseudogene to chromosome 13.

1995 • 376 citations

The formation and stabilization of protein structure

1972 • 372 citations

Phosphorylation of Steroidogenic Acute Regulatory Protein (StAR) Modulates Its Steroidogenic Activity

1997 • 367 citations

Polymer Principles in Protein Structure and Stability

1991 • 308 citations

Steroidogenic acute regulatory protein (StAR) retains activity in the absence of its mitochondrial import sequence: Implications for the mechanism of StAR action

1996 • 295 citations

Intermediate States in Protein Folding

1996 • 283 citations

Neurosteroids: biochemistry, modes of action, and clinical relevance.

1994 • 271 citations

The 30-kDa mitochondrial proteins induced by hormone stimulation in MA-10 mouse Leydig tumor cells are processed from larger precursors.

1991 • 254 citations

Regulation of steroid hormone biosynthesis. Identification of precursors of a phosphoprotein targeted to the mitochondrion in stimulated rat adrenal cortex cells.

1991 • 252 citations

MLN64 contains a domain with homology to the steroidogenic acute regulatory protein (StAR) that stimulates steroidogenesis

1997 • 235 citations

Chemical physics of protein folding

1998 • 231 citations

The Mechanism of Action of Steroidogenic Acute Regulatory Protein (StAR)

1998 • 193 citations

A Protein Dissection Study of a Molten Globule

1994 • 190 citations

Analysis of the steroidogenic acute regulatory protein (StAR) gene in Japanese patients with congenital lipoid adrenal hyperplasia

1997 • 185 citations

Aromatic and Cystine Side-Chain Circular Dichroism in Proteins

1996 • 180 citations

Congenital lipoid adrenal hyperplasia: the human gene knockout for the steroidogenic acute regulatory protein

1997 • 146 citations

Spontaneous Feminization in a 46,XX Female Patient with Congenital Lipoid Adrenal Hyperplasia Due to a Homozygous Frameshift Mutation in the Steroidogenic Acute Regulatory Protein*

1997 • 144 citations

Protein translocation across mitochondrial membranes: What a long, strange trip it is

1995 • 129 citations

T→A transversion 11 bp from a splice acceptor site in the human gene for steroidogenic acute regulatory protein causes congenital lipoid adrenal hyperplasia

1995 • 126 citations

Modeling Protein Stability As Heteropolymer Collapse

1995 • 107 citations

Unfolding of preproteins upon import into mitochondria

1998 • 100 citations

Prenatal diagnosis of congenital lipoid adrenal hyperplasia.

1995 • 73 citations

Incorrect Folding of Steroidogenic Acute Regulatory Protein (StAR) in Congenital Lipoid Adrenal Hyperplasia

1998 • 61 citations

Effects of disruption of the mitochondrial electrochemical gradient on steroidogenesis and the Steroidogenic Acute Regulatory (StAR) proteinProceedings of Xth International Congress on Hormonal Steroids, Quebec, Canada, 17–21 June 1998.

1999 • 60 citations

ATP and A mitochondrial electrochemical gradient are required for functional activity of the steroidogenic acute regulatory (star) protein in isolated mitochondria

1996 • 42 citations

GTP Hydrolysis Is Essential for Protein Import into the Mitochondrial Matrix

1998 • 34 citations

Analysis of the Solution Structure of Human Interleukin-4 Determined by Heteronuclear Three-dimensional Nuclear Magnetic Resonance Techniques

1994 • 27 citations

Acid pH-induced conformational changes in bovine liver rhodanese.

1992 • 12 citations