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The Physiological Relevance of Glucocorticoid Endangerment of the Hippocampusa

Data up to Jan 2025

Published1994
Citations140
References25

Total Citations Per Year

Abstract

References (25)

Exposure to excess glucocorticoids alters dendritic morphology of adult hippocampal pyramidal neurons

1990 • 1,013 citations

Glutamate becomes neurotoxic via the N-methyl-d-aspartate receptor when intracellular energy levels are reduced

1988 • 972 citations

Stress, the Aging Brain, and the Mechanisms of Neuron Death

1992 • 788 citations

Glycogen in astrocytes: possible function as lactate supply for neighboring cells

1993 • 522 citations

Glucocortcoids mediate the stress-induced extracellular accumulation of glutamate

1994 • 377 citations

Biological differences between ischemia, hypoglycemia, and epilepsy

1988 • 331 citations

Postnatal handling attenuates certain neuroendocrine, anatomical, and cognitive dysfunctions associated with aging in female rats

1991 • 251 citations

Glucocorticoid toxicity in the hippocampus: in vitro demonstration

1988 • 219 citations

Glucocorticoid endangerment of hippocampal neurons is NMDA-receptor dependent

1990 • 207 citations

Glucocorticoid toxicity in the hippocampus: Temporal aspects of neuronal vulnerability

1985 • 182 citations

Chronic Dexamethasone Pretreatment Aggravates Ischemic Neuronal Necrosis

1986 • 172 citations

Corticosterone impairs hippocampal neuronal calcium regulation — possible mediating mechanisms

1993 • 140 citations

Glucocorticoids Exacerbate Hypoxic and Hypoglycemic Hippocampal Injury In Vitro: Biochemical Correlates and a Role for Astrocytes

1992 • 137 citations

Corticosterone Exacerbates Kainate‐Induced Alterations in Hippocampal Tau Immunoreactivity and Spectrin Proteolysis In Vivo

1993 • 129 citations

Chemical adrenalectomy reduces hippocampal damage induced by kainic acid

1988 • 124 citations

Excitatory amino acid neurotoxicity at the N-methyl-d-aspartate receptor in cultured neurons: pharmacological characterization

1989 • 111 citations

Dexamethasone Prevents Hypoxic-Ischemic Brain Damage in the Neonatal Rat

1991 • 111 citations

Glucocorticoids accelerate ATP loss following metabolic insults in cultured hippocampal neurons

1994 • 110 citations

Mitochondrial Impairment Reduces the Threshold for in Vivo NMDA-Mediated Neuronal Death in the Striatum

1993 • 110 citations

Excitatory amino acid neurotoxicity at the N-methyl-d-aspartate receptor in cultured neurons: role of the voltage-dependent magnesium block

1989 • 91 citations

Corticosterone accelerates hypoxia- and cyanide-induced ATP loss in cultured hippocampal astrocytes

1992 • 71 citations

Glucocorticoid prevention of neonatal hypoxic-ischemic damage: role of hyperglycemia and antioxidant enzymes

1993 • 50 citations

Adrenalectomy or metyrapone-pretreatment abolishes cerebral metabolic responses to the serotonin agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) in the hippocampus

1992 • 44 citations

Glucocorticoids increase extracellular [3H]d-aspartate overflow in hippocampal cultures during cyanide-induced ischemia

1994 • 32 citations

Steroids and Neuronal Destruction or Stabilization

2007 • 32 citations

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The Physiological Relevance of Glucocorticoid Endangerment of the Hippocampusa (1994) – Annals of the New York Academy of Sciences | Metascience Observatory Explorer