Induction of cyclo-oxygenase 2 in brains of patients with Downʼs syndrome and dementia of Alzheimer type

The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases

1995 • 1,290 citations

Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome

1985 • 1,125 citations

Mechanisms of Neuronal Degeneration in Alzheimer's Disease

1996 • 956 citations

Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro

1995 • 741 citations

A radical hypothesis for neurodegeneration

1993 • 727 citations

Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence.

1988 • 604 citations

Evidence for a peroxide-initiated free radical mechanism of prostaglandin biosynthesis.

1980 • 481 citations

Autopsy Samples of Alzheimer's Cortex Show Increased Peroxidation In Vitro

1990 • 456 citations

Amyloidogenicity of beta A4 and beta A4-bearing amyloid protein precursor fragments by metal-catalyzed oxidation.

1992 • 344 citations

Free radicals in central nervous system ischemia.

1990 • 251 citations

Eicosanoids in synaptic transmission.

1994 • 135 citations