The neuroprotective effect of deferoxamine in the hypoxic-ischemic immature mouse brain

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.

1995 • 5,971 citations

Oxidative Stress, Glutamate, and Neurodegenerative Disorders

1993 • 3,746 citations

The influence of immaturity on hypoxic‐ischemic brain damage in the rat

1981 • 2,073 citations

Inhibition of the iron-catalysed formation of hydroxyl radicals from superoxide and of lipid peroxidation by desferrioxamine

1979 • 637 citations

Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase.

1991 • 591 citations

Transgenic mice with increased Cu/Zn-superoxide dismutase activity: animal model of dosage effects in Down syndrome.

1987 • 461 citations

Protection against tissue damage in vivo by desferrioxamine: What is its mechanism of action?

1989 • 385 citations

Developmental changes in transferrin and iron uptake by the brain in the rat

1990 • 219 citations

Deferoxamine posttreatment reduces ischemic brain injury in neonatal rats.

1994 • 207 citations

Brain Injury after Perinatal Hypoxia-Ischemia Is Exacerbated in Copper/Zinc Superoxide Dismutase Transgenic Mice

1996 • 193 citations

Copper/zinc superoxide dismutase transgenic brain accumulates hydrogen peroxide after perinatal hypoxia ischemia

1998 • 183 citations

Changes in iron histochemistry after hypoxic-ischemic brain injury in the neonatal rat

1999 • 138 citations

Hypoxic-ischemic Encephalopathy: Therapeutic Approaches Against Microvascular Injury, and Role of Neutrophils, PAF, and Free Radicals

1995 • 107 citations

An autoradiographic study of the uptake and distribution of iron by the brain of the young rat

1990 • 98 citations

Hydrogen peroxide is selectively toxic to immature murine neurons in vitro

1997 • 51 citations

Effects of chelators on iron uptake and release by the brain in the rat

1994 • 39 citations

Antioxidant properties of deferoxamine

1994 • 23 citations

Development of the rat corticospinal tract through an altered glial environment

1990 • 16 citations

Excitatory amino acids in neonatal brain: contributions to pathology and therapeutic strategies.

1995 • 15 citations