Genetic and Environmental Factors in Prostate Cancer Genesis:Identifying High-Risk Cohorts

Linkage of Early-Onset Familial Breast Cancer to Chromosome 17q21

1990 • 2,505 citations

Genetic variation at five trimeric and tetrameric tandem repeat loci in four human population groups

1992 • 1,468 citations

Studies of Japanese migrants. I. Mortality from cancer and other diseases among Japanese in the United States.

1968 • 1,105 citations

Differentiation of mouse myeloid leukemia cells induced by 1 alpha,25-dihydroxyvitamin D3.

1981 • 1,025 citations

Major Susceptibility Locus for Prostate Cancer on Chromosome 1 Suggested by a Genome-Wide Search

1996 • 834 citations

Mendelian inheritance of familial prostate cancer.

1992 • 803 citations

Family history and the risk of prostate cancer

1990 • 729 citations

Evidence for a prostate cancer susceptibility locus on the X chromosome.

1998 • 682 citations

Geographic patterns of prostate cancer mortality. Evidence for a protective effect of ultraviolet radiation

1992 • 657 citations

Expression of the cellular adhesion molecule E-cadherin is reduced or absent in high-grade prostate cancer.

1992 • 612 citations

Contribution of trans-acting factor alleles to normal physiological variability: vitamin D receptor gene polymorphism and circulating osteocalcin.

1992 • 604 citations

Association of Prostate Cancer Risk With Genetic Polymorphisms in Vitamin D Receptor and Androgen Receptor

1997 • 599 citations

Is vitamin D deficiency a risk factor for prostate cancer? (Hypothesis).

1990 • 514 citations

Regulation of myc gene expression in HL-60 leukaemia cells by a vitamin D metabolite

1983 • 500 citations

The CAG and GGC microsatellites of the androgen receptor gene are in linkage disequilibrium in men with prostate cancer.

1995 • 492 citations

Antiproliferative effects of 1,25-dihydroxyvitamin D3 on primary cultures of human prostatic cells.

1994 • 489 citations

Allelic loss of chromosomes 16q and 10q in human prostate cancer.

1990 • 456 citations

Predisposing Gene for Early-Onset Prostate Cancer, Localized on Chromosome 1q42.2-43

1998 • 365 citations

Vitamin D and prostate cancer: a prediagnostic study with stored sera.

1993 • 357 citations

Suppression of in vivo growth of human cancer solid tumor xenografts by 1,25-dihydroxyvitamin D3.

1987 • 312 citations

Deletion mapping of chromosomes 8, 10, and 16 in human prostatic carcinoma

1991 • 286 citations

Nutrition and prostate cancer

1996 • 256 citations

Clinical Evidence for and Implications of the Multistep Development of Prostate Cancer

1990 • 256 citations

Loss of heterozygosity of the BRCA1 and other loci on chromosome 17q in human prostate cancer.

1995 • 216 citations

Studies of Vitamin D Deficiency in Man

1975 • 199 citations

Risk of prostate, ovarian, and endometrial cancer among relatives of women with breast cancer.

1992 • 188 citations

Familial prostate cancer in sweden: A nationwide register cohort study

1996 • 155 citations

Rye bran and soy protein delay growth and increase apoptosis of human LNCaP prostate adenocarcinoma in nude mice

2000 • 154 citations

Allelotyping of human prostatic adenocarcinoma

1991 • 153 citations

Risk of Cancer in Relatives of Prostate Cancer Probands

1995 • 151 citations

Studies of Genetic Factors in Prostate Cancer in a Twin Population

1994 • 150 citations

Cadmium and prostate cancer

1994 • 147 citations

Studies in the epidemiology of prostatic cancer: expanded sampling.

1977 • 133 citations

Total Food Consumption and Body Mass Index in Relation to Prostate Cancer Risk: A Case-Control Study in Sweden with Prospectively Collected Exposure Data

1996 • 129 citations

Farming and Prostate Cancer Mortality

1993 • 128 citations

Sexual factors in the epidemiology of cancer of the prostate

1971 • 126 citations

Linkage Analysis of Chromosome 1q Markers in 136 Prostate Cancer Families

1998 • 123 citations

Original Articles

1995 • 122 citations

Linkage analysis of chromosome 17q markers and breast-ovarian cancer in Icelandic families, and possible relationship to prostatic cancer.

1993 • 120 citations

Original Articles: Prostate Cancer: Pathological Features of Hereditary Prostate Cancer

1995 • 118 citations

ANDROGEN LEVELS IN THE PLASMA AND PROSTATIC TISSUES OF PATIENTS WITH BENIGN HYPERTROPHY AND CARCINOMA OF THE PROSTATE

1976 • 118 citations

Some epidemiologic variables in prostatic carcinoma in California

1974 • 114 citations

Inhibitory effects of soy and rye diets on the development of Dunning R3327 prostate adenocarcinoma in rats

1998 • 114 citations

Familial factors affecting prostatic cancer risk and plasma sex‐steroid levels

1985 • 114 citations

PLASMA STEROID AND PROTEIN HORMONE CONCENTRATIONS IN PATIENTS WITH PROSTATIC CARCINOMA, BEFORE AND DURING OESTROGEN THERAPY

1976 • 110 citations

Diet and urinary steroids in black and white North American men and black South African men.

1979 • 110 citations

Epidemiologic study of prostatic cancer: preliminary report.

1977 • 103 citations

Familial Prostatic Cancer Risk and Low Testosterone*

1982 • 101 citations

Inhibition of tumor promotion in mouse skin by 1 alpha,25-dihydroxyvitamin D3.

1985 • 97 citations

Identification of two distinct deleted regions on chromosome 13 in prostate cancer

1998 • 94 citations

Risk factors for prostate cancer.

1995 • 93 citations

Prevalence of androgen receptor gene mutations in latent prostatic carcinomas from Japanese men.

1995 • 92 citations

A Case‐Control Study of Prostatic Cancer With Reference to Dietary Habits

1988 • 89 citations

Prostate cancer in pesticide applicators in Swedish agriculture

1998 • 86 citations

Cancer risks among male farmers in Sweden

1995 • 82 citations

Role of cadmium in carcinogenesis with special reference to cancer of the prostate

1981 • 81 citations

Abnormal levels of plasma hormones in men with prostate cancer: Evidence toward a “two‐disease” theory

1982 • 78 citations

Case-control study of prostatic cancer in employees of the United Kingdom Atomic Energy Authority.

1993 • 78 citations

Calcium, vitamin D-endocrine system, and parathyroid hormone in black and white males

1987 • 77 citations

Familial Clustering of Breast and Prostate Cancers and Risk of Postmenopausal Breast Cancer

1994 • 76 citations

Mapping of Regions of Physical Deletion on Chromosome 16q in Prostate Cancer Cells by Fluorescence in Situ Hybridization (FISH)

1995 • 73 citations

Abnormal androgen receptor binding affinity in subjects with Kennedy's disease (spinal and bulbar muscular atrophy).

1995 • 70 citations

Vitamin A and prostate cancer in elderly men: enhancement of risk.

1987 • 67 citations

Evidence for a Tumor Suppressor Gene Distal to BRCA1 in Prostate Cancer

1996 • 64 citations

The preventive role of diet in prostatic disease

1996 • 64 citations

Family History and the Risk of Prostatic Carcinoma in a High Risk Group of Urological Patients

1995 • 62 citations

Growth of Dunning Transplantable Prostate Adenocarcinomas in Rats Fed Diets with Various Fat Contents

1988 • 61 citations

Suppression of malignant phenotype in a human prostate cancer cell line by fragments of normal chromosomal region 17q.

1995 • 54 citations

Promotional effects of testosterone and dietary fat on prostate carcinogenesis in genetically susceptible rats

1985 • 50 citations

INCIDENCE OF CANCER IN NEGROES IN WASHINGTON, D.C. AND SELECTED AFRICAN CITIES

1972 • 43 citations

Characterization of prostatic carcinoma among blacks: a continuation report.

1977 • 42 citations

Plasma steroids in benign prostatic hypertrophy and carcinoma of the prostate

1982 • 41 citations

p53 Gene Mutations in Human Prostate Cancers in Japan: Different Mutation Spectra between Japan and Western Countries

1994 • 38 citations

Familial effects of prostate and other cancers on lifetime breast cancer risk

1993 • 34 citations

Chromosome 16q24 deletion and decreased E-cadherin expression: Possible association with metastatic potential in prostate cancer

1998 • 33 citations

p53 Mutations Occur in Clinical, but Not Latent, Human Prostate Carcinoma

1995 • 31 citations

Geographical epidemiology of prostate cancer: is there an association with infection?

1995 • 4 citations