Induction of neuronal nitric oxide synthase by methylmercury in the cerebellum

Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme.

1990 • 3,304 citations

Glutamate, nitric oxide and cell-cell signalling in the nervous system

1991 • 2,406 citations

A pathological study of Minamata disease in Japan

1962 • 393 citations

Activation of calmodulin by various metal cations as a function of ionic radius.

1984 • 336 citations

Nitric oxide, superoxide and peroxynitrite: Putative mediators of NMDA-induced cell death in cerebellar granule cells

1993 • 192 citations

Regional Variations in the Pharmacology of NMDA Receptor Channel Blockers: Implications for Therapeutic Potential

1995 • 137 citations

Cytoskeletal Breakdown and Apoptosis Elicited by NO Donors in Cerebellar Granule Cells Require NMDA Receptor Activation

1996 • 130 citations

Methylmercury-induced alterations in excitatory amino acid transport in rat primary astrocyte cultures

1993 • 107 citations

A model of acute methyl mercury intoxication in rats.

1972 • 107 citations

Effects of NMDA antagonists, MK-801 and CPP, upon local cerebral glucose use

1989 • 106 citations

Cerebellar Injury Induces NADPH Diaphorase in Purkinje and Inferior Olivary Neurons in the Rat

1994 • 84 citations

Methyl Mercury Increases Intracellular Ca²⁺ and Inositol Phosphate Levels in Cultured Cerebellar Granule Neurons

1993 • 83 citations

Cerebellar injury induces NOS in Purkinje cells and cerebellar afferent neurons

1994 • 83 citations

Glutamate receptors mediate dynamic regulation of nitric oxide synthase expression in cerebellar granule cells

1996 • 75 citations

Inhibition of Phorbol Ester Binding and Protein Kinase C Activity by Heavy Metals

1989 • 68 citations

Excitotoxic insult due to ibogaine leads to delayed induction of neuronal NOS in Purkinje cells

1995 • 61 citations

Cerebellar nitric oxide synthase activity is reduced in nervous and Purkinje cell degeneration mutants but not in climbing fiber-lesioned mice

1993 • 57 citations

The localization of mercury and metallothionein in the cerebellum of rats experimentally exposed to methylmercury

1994 • 51 citations

Role of nitric oxide in the cerebellar degeneration during methylmercury intoxication

1997 • 43 citations

Purkinje cells express neuronal nitric oxide synthase after methylmercury administration

1996 • 33 citations

Action of Mercurials on Activity of Partially Purified Soluble Protein Kinase C from Mice Brain

1988 • 31 citations

Effect of methylmercury (CH3HgCl) injury on nitric oxide synthase (NOS) activity in cultured human umbilical vascular endothelial cells

1995 • 30 citations

Cerebellar excitatory amino acid binding sites in normal, granuloprival, and purkinje cell-deficient mice

1991 • 20 citations

Methyl Mercury Stimulates Protein ³²P Phospholabeling in Cerebellar Granule Cell Culture

1990 • 19 citations

Effects of chronic administration of MK-801 upon local cerebral glucose utilisation and ligand binding to the NMDA receptor complex

1991 • 15 citations

Modulation by protein kinase C of nitric oxide and cyclic GMP formation in cultured cerebellar granule cells

1996 • 13 citations

Cerebellar nitric oxide synthase, cGMP and motor function in two lines of cerebellar mutant mice, Staggerer and Wriggle Mouse Sagami

1994 • 10 citations

The effect of methylmercury (CH3HgCl) on the production of endothelium-derived relaxing factor (EDRF) by cultured human umbilical vascular endothelial cells based on its anti-aggregatory effect on human platelets

1995 • 8 citations

Protein kinase C subspecies in hippocampus and striatum of reserpinized rat brain

1994 • 8 citations

Reduced membrane-associated protein kinase C(β) immunoreactivity in the hippocampus of reserpinized rat brain

1993 • 4 citations