Age-related structural modulation of T lymphocyte-associated CD45 isoforms

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

The Leukocyte Common Antigen Family

1989 • 741 citations

CD45: An Emerging Role as a Protein Tyrosine Phosphatase Required for Lymphocyte Activation and Development

1994 • 733 citations

Lifespan of human lymphocyte subsets defined by CD45 isoforms

1992 • 642 citations

The T Cell Receptor as a Multicomponent Signalling Machine: CD4/CD8 Coreceptors and CD45 in T Cell Activation

1992 • 539 citations

Normal B lymphocyte development but impaired T cell maturation in CD45-Exon6 protein tyrosine phosphatase-deficient mice

1993 • 509 citations

The leukocyte common antigen (CD45): a putative receptor-linked protein tyrosine phosphatase.

1988 • 435 citations

CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation.

1996 • 382 citations

Mechanisms of Alternative Pre-mRNA Splicing

1991 • 257 citations

CD45 isoforms expression on CD4+ and CD8+ T cells throughout life, from newborns to centenarians: implications for T cell memory

1996 • 254 citations

Differential age-change in the numbers of CD4+CD45RA+ DC4+CD29+ T cell subsets in human peripheral blood

1992 • 239 citations

Natural ligands of the B cell adhesion molecule CD22 beta can be masked by 9-O-acetylation of sialic acids.

1994 • 183 citations

Signal transduction through cd4 receptors: stimulatory vs. inhibitory activity is regulated by cd4 proximity to the cd31t cell receptor

1988 • 166 citations

Specific interaction of the CD45 protein-tyrosine phosphatase with tyrosine-phosphorylated CD3 zeta chain.

1994 • 163 citations

Lymphocyte specific heterogeneity in the rat leucocyte common antigen (T200) is due to differences in polypeptide sequences near the NH2-terminus.

1987 • 159 citations

Regulation of alpha 2,3-sialyltransferase expression correlates with conversion of peanut agglutinin (PNA)+ to PNA- phenotype in developing thymocytes.

1993 • 142 citations

Developmental Immunology

1970 • 122 citations

Leukocyte cell surface enzymology: CD45 (LCA, T200) is a protein tyrosine phosphatase

1989 • 99 citations

Characterization of Terminal Sialic Acid Linkages on Human Thymocytes

1996 • 93 citations

Expression of variable exon A-, B-, and C-specific CD45 determinants on peripheral and thymic T cell populations.

1992 • 65 citations

Age‐related increase of CD45RO⁺ lymphocytes in physically active adults

1993 • 65 citations

Different classes of T lymphocytes have different mRNAs for the leukocyte-common antigen, T200.

1986 • 61 citations

Mechanisms of Lymphocyte Activation and Immune Regulation

1987 • 44 citations

Developmental sequence of T200 antigen modifications in murine T cells.

1987 • 44 citations

Biochemical nature and topographic localization of epitopes defining four distinct CD45 antigen specificities. Conventional CD45, CD45R, 180 kDa (UCHL1) and 220/205/190 kDa.

1989 • 34 citations

Structural study of the O‐linked sugar chains of human leukocyte tyrosine phosphatase CD45

1998 • 34 citations

Glycosylation of CD45: carbohydrate composition and its role in acquisition of CD45RO and CD45RB T cell maturation‐related antigen specificities during biosynthesis

1990 • 33 citations

Further data on the selective expression of Ly-5 isoforms

1990 • 19 citations

Specific CD45 Isoforms Regulate T Cell Ontogeny and Are Functionally Distinct in Modifying Immune Activation

1994 • 4 citations