Glucose-induced downregulation of angiotensin II and arginine vasopressin receptors in cultured rat aortic vascular smooth muscle cells. Role of protein kinase C.

Studies and Perspectives of Protein Kinase C

1986 • 5,148 citations

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

1988 • 4,243 citations

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

1984 • 2,728 citations

The smooth muscle cell in culture

1979 • 1,546 citations

Phorbol esters increase the amount of Ca2+, phospholipid-dependent protein kinase associated with plasma membrane

1983 • 1,304 citations

Glomerular hemodynamics in experimental diabetes mellitus

1981 • 785 citations

THE PROTEIN KINASE C FAMILY: HETEROGENEITY AND ITS IMPLICATIONS

1989 • 739 citations

Predominance of hemodynamic rather than metabolic factors in the pathogenesis of diabetic glomerulopathy.

1985 • 532 citations

Protein kinase C activation by diacylglycerol second messengers

1986 • 498 citations

Pathogenesis of Sodium and Water Retention in High-Output and Low-Output Cardiac Failure, Nephrotic Syndrome, Cirrhosis, and Pregnancy

1988 • 486 citations

Pathogenesis of Sodium and Water Retention in High-Output and Low-Output Cardiac Failure, Nephrotic Syndrome, Cirrhosis, and Pregnancy

1988 • 333 citations

Phorbol esters promote alpha 1-adrenergic receptor phosphorylation and receptor uncoupling from inositol phospholipid metabolism.

1985 • 332 citations

Protein kinase C is activated in glomeruli from streptozotocin diabetic rats. Possible mediation by glucose.

1989 • 324 citations

Pathogenesis of diabetic microangiopathy. The hemodynamic view

1986 • 320 citations

Phorbol esters stimulate the phosphorylation of receptors for insulin and somatomedin C.

1983 • 291 citations

Phorbol esters modulate insulin receptor phosphorylation and insulin action in cultured hepatoma cells.

1984 • 260 citations

Tumor-promoting phorbol diesters cause the phosphorylation of epidermal growth factor receptors in normal human fibroblasts at threonine-654.

1985 • 244 citations

Regulation of Protein Kinase C by Nerve Growth Factor, Epidermal Growth Factor, and Phorbol Esters in PC12 Pheochromocytoma Cells

1989 • 219 citations

Increase in Diacylglycerol Mass in Isolated Glomeruli by Glucose From De Novo Synthesis of Glycerolipids

1990 • 219 citations

Retinal Vascular Autoregulation in Diabetes Mellitus

1982 • 153 citations

Differential regulation of protein kinase C and (Na,K)-adenosine triphosphatase activities by elevated glucose levels in retinal capillary endothelial cells.

1989 • 140 citations

Role of calcium and cyclic adenosine 3′:5′ monophosphate in regulating smooth muscle contraction

1979 • 132 citations

Role of receptor cycling in the regulation of angiotensin II surface receptor number and angiotensin II uptake in rat vascular smooth muscle cells.

1989 • 131 citations

Impaired autoregulation of glomerular filtration rate in Type 1 (insulin-dependent) diabetic patients with nephropathy

1984 • 128 citations

Chronically Impaired Autoregulation of Cerebral Blood Flow in Long-Term Diabetics

1975 • 117 citations

The effect of acute hyperglycaemia on the retinal circulation of the normal cat

1980 • 91 citations

Overexpression of protein kinase C alpha-subtype in Swiss/3T3 fibroblasts causes loss of both high and low affinity receptor numbers for epidermal growth factor.

1990 • 76 citations

Reduced Glomerular Angiotensin II Receptor Density in Diabetes Mellitus in the Rat: Time Course and Mechanism*

1987 • 71 citations

Angiotensin II surface receptor coupling to inositol trisphosphate formation in vascular smooth muscle cells.

1990 • 67 citations

Alteration of 1,2-Diacylglycerol Content in Myocardium From Diabetic Rats

1988 • 65 citations

Detection of nerve growth factor and epidermal growth factor-regulated protein kinases in PC12 cells with synthetic peptide substrates.

1989 • 55 citations

Tumour promotor 12‐O‐tetradecanoylphorbol 13‐acetate inhibits angiotensin II‐induced inositol phosphate production and cytosolic Ca²⁺ rise in rat renal mesangial cells

1986 • 51 citations

Vascular responsiveness and serum biochemical parameters in alloxan diabetes mellitus

1980 • 49 citations

Phorbol esters inhibit agonist-stimulated phosphoinositide hydrolysis in neuronal primary cultures

1987 • 42 citations

Protein kinase C from rat renal mesangial cells: Its role in homologous desensitization of angiotensin II-induced polyphosphoinositide hydrolysis

1988 • 40 citations

Mechanism of cellular effect of phorbol esters on action of arginine vasopressin and angiotensin II on rat vascular smooth muscle cells in culture

1988 • 40 citations

Autoregulation of Renal Blood Flow in Streptozocin-Induced Diabetic Rats

1989 • 36 citations

Impaired autoregulation of blood flow in skeletal muscle and subcutaneous tissue in long-term type 1 (insulin-dependent) diabetic patients with microangiopathy

1983 • 32 citations

The Protein Kinase C Family: Heterogeneity And Its Implications

1989 • 28 citations

Interaction of atriopeptin III and vasopressin on calcium kinetics and contraction of aortic smooth muscle cells.

1988 • 28 citations

Mechanisms of rapid desensitization to arginine vasopressin in vascular smooth muscle cells

1991 • 25 citations

Phorbol esters and arginine vasopressin in vascular smooth muscle cell activation

1989 • 25 citations

Alteration of 1,2-diacylglycerol content in myocardium from diabetic rats

1988 • 24 citations

Interaction of arginine vasopressin and angiotensin II on Ca2+ in vascular smooth muscle cells

1990 • 22 citations

Studies of renal autoregulation in pancreatectomized and streptozotocin diabetic rats

1990 • 22 citations

Characterization and Localization of Calcium/Phospholipid-Dependent Protein Kinase-C during Diabetic Renal Growth

1988 • 20 citations

Effects of extra- and intracellular pH on vascular action of arginine vasopressin

1991 • 13 citations

Platelet Aggregation and Vasopressin Receptors in Patients with Diabetes Mellitus

1988 • 9 citations

Platelet thromboxane A2 receptors in type I diabetes

1991 • 9 citations

Mechanisms of the vascular effect of pressor hormones

1988 • 7 citations

Hemodynamic factors in the pathogenesis of diabetic nephropathy

1988 • 4 citations