DNA Markers for Nervous System Diseases

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Construction of a genetic linkage map in man using restriction fragment length polymorphisms.

1980 • 8,270 citations

Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis

1984 • 2,847 citations

A polymorphic DNA marker genetically linked to Huntington's disease

1983 • 2,329 citations

Changes in size and secondary structure of the ribosomal transcription unit during vertebrate evolution

1975 • 1,188 citations

Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferase.

1981 • 1,048 citations

DNA fragments differing by single base-pair substitutions are separated in denaturing gradient gels: correspondence with melting theory.

1983 • 895 citations

Von Hippel-Lindau disease: clinical and pathological manifestations in nine families with 50 affected members

1976 • 302 citations

Cloning of a representative genomic library of the human X chromosome after sorting by flow cytometry

1981 • 277 citations

Huntington’s Chorea

1981 • 254 citations

Central neurofibromatosis with bilateral acoustic neuroma: Genetic, clinical and biochemical distinctions from peripheral neurofibromatosis

1980 • 223 citations

Isolation and localization of DNA segments from specific human chromosomes

1980 • 220 citations

Von Hippel-Lindau Disease

1976 • 220 citations

Defizienz an den kurzen Armen eines Chromosomes Nr. 4

1965 • 216 citations

A Family With Histologically Confirmed Alzheimer's Disease

1983 • 176 citations

Open reading frame expression vectors: a general method for antigen production in Escherichia coli using protein fusions to beta-galactosidase.

1983 • 108 citations

Open reading frame cloning: identification, cloning, and expression of open reading frame DNA.

1982 • 70 citations

The mutation rate to Huntington's chorea

1982 • 43 citations

Mutation in Huntington's chorea.

1969 • 36 citations

Huntington's disease: implications of associated cellular radiosensitivity

1981 • 26 citations

Eukaryotic chromosome transfer: linkage of the murine major histocompatibility complex to an inserted dominant selectable marker.

1984 • 22 citations

Somatic cell hybrid selection with a transfectable dominant marker

1984 • 19 citations

Recombinant DNA approach to neurogenetic disorders

1982 • 11 citations

Altered red cell osmotic fragility in Huntington disease (HD)

1982 • 8 citations

Human Gene Mapping 7

1983 • 4 citations

Experience is the child of thought

1979 • 1 citations

PREFACE

1970 • 1 citations