A microspectrofluorometric approach for the study of Benzo(a)pyrene and Dibenzo(a, h)anthracene metabolization in single living cells

Fluorescence Assay in Biology and Medicine

1963 • 642 citations

A microsome-dependent binding of benzo[a]pyrene to DNA.

1969 • 332 citations

Enzyme-catalysed reactions of polycyclic hydrocarbons with deoxyribonucleic acid and protein in vitro

1968 • 261 citations

Inhibition of the carcinogenic action of benzo(a)pyrene by flavones.

1970 • 210 citations

Formation of K-region epoxides as microsomal metabolites of pyrene and benzo[a]pyrene

1972 • 199 citations

In Vitro Transformation of Rodent Cells by K-Region Derivatives of Polycyclic Hydrocarbons

1971 • 190 citations

An epoxide is an intermediate in the microsomal metabolism of the chemical carcinogen, dibenz(a,h)anthracene

1971 • 172 citations

Mutagenicity to Mammalian Cells of Epoxides and Other Derivatives of Polycyclic Hydrocarbons

1971 • 172 citations

Some Factors Influencing the Ultraviolet Absorption Spectra of Polynuclear Aromatic Compounds. I. A General Survey¹

1945 • 171 citations

Studies on the formation of protein-bound derivatives of 3,4-benzpyrene in the epidermal fraction of mouse skin.

1951 • 165 citations

K-region and non-K-region metabolism of benzo(a)pyrene by rat liver microsomes.

1973 • 143 citations

The metabolism of benz[a]anthracene and dibenz[a,h]anthracene and their 5,6-epoxy-5,6-dihydro derivatives by rat-liver homogenates

1965 • 129 citations

Microsomal hydroxylases: induction and role in polycyclic hydrocarbon carcinogenesis and toxicity.

1972 • 119 citations

Uptake of Hydrocarbon Carcinogens by Lysosomes

1964 • 101 citations

Lactic Dehydrogenase

1959 • 86 citations

The carcinogenic activities in mice of compounds related to benz[a]anthracene

1967 • 77 citations

Intermediary Metabolism of Benzo[<italic>α</italic>]pyrene in the Rat<xref ref-type="fn" rid="fn1">2</xref>

1962 • 66 citations

Effect of enzyme induction on the metabolism of benzo(a)pyrene and 3'-methyl-4-monomethylaminoazobenzene in the pregnant and fetal rat.

1972 • 57 citations

The relation of metabolism to macromolecular binding of the carcinogen benzo[a]pyrene, by mouse embryo cells in culture

1970 • 49 citations

Comparative Studies on the Interaction of Benzo[<italic>a</italic>]pyrene With Cells Derived From Poikilothermic and Homeothermic Vertebrates. I. Metabolism of Benzo[<italic>a</italic>]pyrene<xref ref-type="fn" rid="FN2">2</xref>

1970 • 48 citations

Benzpyrene Hydroxylase Induction by Polycyclic Hydrocarbons in Hamster Embryonic Cells Grown in vitro

1967 • 48 citations

The effects of two isomeric benzoflavones on aryl hydrocarbon hydroxylase and the toxicity and carcinogenicity of polycyclic hydrocarbons.

1972 • 42 citations

The biochemistry of benzpyrene; a survey, and new methods of analysis.

1946 • 38 citations

The influence of microelectrophoretically introduced metabolites on pyridine nucleotide reduction in giant tissue culture ascites cells

1966 • 34 citations

Benzpyrene hydroxylase activity and its induction by methylcholanthrene in Morris hepatomas, in host livers, in adult livers, and in rat liver during development.

1970 • 33 citations

Benzo(alpha)pyrene-metabolizing enzyme activity of livers of various strains of mice.

1970 • 27 citations

Studies on the metabolic products obtained from mouse skin after painting with 3, 4-benzpyrene.

1956 • 17 citations

32-msec scan of the NAD(P)H fluorescence spectrum in single living cells

1973 • 16 citations

Rapid multichannel microfluorometry for metabolic and spectral studies in single living cells

1973 • 16 citations

Rapid microspectrofluorimetry for biochemical and metabolic studies in single living cells

1974 • 16 citations

SPECTROSCOPIC ANALYSIS OF CARCINOGENIC HYDROCARBONS IN BIOLOGIC INTERACTION IN VIVO AND IN VITRO.

1963 • 15 citations

A fluorescence microscopic study of methodologic effects on the intranuclear distribution of benzo(alpha)pyrene.

1969 • 10 citations

Quantitation of Aryl Hydrocarbon Hydroxylase Activity in Individual Fetal Hamster Cells In Vitro<xref ref-type="fn" rid="FN2">2</xref>

1972 • 9 citations