Finally! the Brambell receptor (FcRB)

Fundamental Immunology

1994 • 903 citations

THE COVALENT STRUCTURE OF AN ENTIRE γG IMMUNOGLOBULIN MOLECULE

1969 • 869 citations

The Theory of Tracer Experiments with ¹³¹I-Labelled Plasma Proteins

1957 • 834 citations

Metabolism of Immunoglobulins

2015 • 733 citations

An Fc receptor structurally related to MHC class I antigens

1989 • 711 citations

The protection receptor for IgG catabolism is the beta2-microglobulin-containing neonatal intestinal transport receptor.

1996 • 671 citations

The transmission of passive immunity from mother to young

1970 • 612 citations

Receptor-Mediated Antigen Uptake and its Effect on Antigen Presentation to Class II-Restricted T Lymphocytes

1990 • 605 citations

Receptor-mediated endocytosis of transferrin in K562 cells.

1983 • 576 citations

The Sequence of Amino Acid Residues in Bovine Pancreatic Ribonuclease: Revisions and Confirmations

1963 • 562 citations

Abnormally short serum half‐lives of IgG in β2‐microglobulin‐deficient mice

1996 • 462 citations

THE TRANSMISSION OF IMMUNITY FROM MOTHER TO YOUNG AND THE CATABOLISM OF IMMUNOGLOBULINS

1966 • 445 citations

The Ingestion of Proteins and Colloidal Materials by Columnar Absorptive Cells of the Small Intestine in Suckling Rats and Mice

1959 • 440 citations

A Theoretical Model of γ-Globulin Catabolism

1964 • 440 citations

Movement of internalized ligand–receptor complexes along a continuous endosomal reticulum

1990 • 428 citations

Crystal structure of the complex of rat neonatal Fc receptor with Fc

1995 • 382 citations

Two distinct subpopulations of endosomes involved in membrane recycling and transport to lysosomes

1988 • 377 citations

The low density lipoprotein receptor. Identification of amino acids in cytoplasmic domain required for rapid endocytosis.

1987 • 355 citations

INTESTINAL TRANSPORT OF ANTIBODIES IN THE NEWBORN RAT

1973 • 349 citations

Isolation from human placenta of the IgG transporter, FcRn, and localization to the syncytiotrophoblast: implications for maternal-fetal antibody transport.

1996 • 345 citations

A major histocompatibility complex class I-like Fc receptor cloned from human placenta: possible role in transfer of immunoglobulin G from mother to fetus.

1994 • 342 citations

Isolation and characterization of an Fc receptor from neonatal rat small intestine

1985 • 332 citations

Crystal structure at 2.2 Å resolution of the MHC-related neonatal Fc receptor

1994 • 320 citations

Increased clearance of IgG in mice that lack β₂‐microglobulin: possible protective role of FcRn

1996 • 317 citations

An IgG‐transporting Fc receptor expressed in the syncytiotrophoblast of human placenta

1996 • 311 citations

Fc RECEPTORS AND THEIR INTERACTIONS WITH IMMUNOGLOBULINS

1996 • 309 citations

Analysis of the pH Dependence of the Neonatal Fc Receptor/Immunoglobulin G Interaction Using Antibody and Receptor Variants

1995 • 308 citations

Receptor-mediated transport of IgG.

1984 • 283 citations

Invariants in Experimental Data on Linear Kinetics and the Formulation of Models

1956 • 280 citations

The mechanism of intestinal uptake and transcellular transport of IgG in the neonatal rat

1972 • 279 citations

pH-dependent binding of immunoglobulins to intestinal cells of the neonatal rat.

1976 • 260 citations

THE CATABOLISM OF HOMOLOGOUS AND HETEROLOGOUS 7S GAMMA GLOBULIN FRAGMENTS

1965 • 235 citations

Separation and Isolation of Fractions of Rabbit Gamma-Globulin containing the Antibody and Antigenic Combining Sites

1958 • 210 citations

Requirement for a beta 2-microglobulin-associated Fc receptor for acquisition of maternal IgG by fetal and neonatal mice.

1995 • 192 citations

Membrane Dynamics in Endocytosis

1996 • 186 citations

Distribution of immunoglobulin G receptors in the small intestine of the young rat.

1980 • 186 citations

Internalization and rapid recycling of macrophage Fc receptors tagged with monovalent antireceptor antibody: possible role of a prelysosomal compartment.

1984 • 176 citations

FACTORS CONTROLLING SERUM γ-GLOBULIN CONCENTRATION

1963 • 172 citations

Some Formal Approaches to the Analysis of Kinetic Data in Terms of Linear Compartmental Systems

1962 • 169 citations

Ueber Immunität durch Vererbung und Säugung

1892 • 159 citations

The absorption of antibodies from immune sera by the gut of the young rat

1955 • 159 citations

Mouse MHC class I-like Fc receptor encoded outside the MHC.

1993 • 151 citations

Isolation and characterization of the Fc receptor from the fetal yolk sac of the rat.

1990 • 149 citations

Preferential interaction of albumin-binding proteins, gp30 and gp18, with conformationally modified albumins. Presence in many cells and tissues with a possible role in catabolism.

1992 • 147 citations

Investigation of the interaction between the class I MHC-related Fc receptor and its immunoglobulin G ligand

1994 • 143 citations

A major histocompatibility complex class I-related Fc receptor for IgG on rat hepatocytes.

1995 • 143 citations

SELECTIVE ANTIBODY TRANSPORT IN THE PROXIMAL SMALL INTESTINE OF THE NEONATAL RAT

1970 • 142 citations

Localization of the site of the murine IgG1 molecule that is involved in binding to the murine intestinal Fc receptor

1994 • 140 citations

The relative transmission of the fractions of papain hydrolyzed homologous γ-globulin from the uterine cavity to the foetal circulation in the rabbit

1960 • 117 citations

Identifying amino acid residues that influence plasma clearance of murine IgG1 fragments by site‐directed mutagenesis

1994 • 117 citations

BIOPHYSICAL AND IMMUNOLOGICAL STUDIES ON BOVINE IMMUNE GLOBULINS WITH EVIDENCE FOR SELECTIVE TRANSPORT WITHIN THE MAMMARY GLAND FROM MATERNAL PLASMA TO COLOSTRUM.

1965 • 116 citations

The stoichiometry and affinity of the interaction of murine Fc fragments with the MHC class I-related receptor, FcRn

1996 • 111 citations

The class I major histocompatibility complex related Fc receptor shows pH-dependent stability differences correlating with immunoglobulin binding and release

1993 • 103 citations

Expression and crystallization of a soluble and functional form of an Fc receptor related to class I histocompatibility molecules.

1992 • 97 citations

THE BEHAVIOR OF I¹³¹‐LABELED PLASMA PROTEINS IN VIVO

1957 • 93 citations

Nature and Origin of the Proteins of Bile

1974 • 92 citations

The transmission of immune globulins from the mother to the foetal and newborn young

1969 • 90 citations

Intestinal Absorption of Immune Complexes by Neonatal Rats: A Route of Antigen Transfer from Mother to Young

1979 • 84 citations

Crystallization and Stoichiometry of Binding of a Complex between a Rat Intestinal Fc Receptor and Fc

1993 • 83 citations

RELATIONSHIP BETWEEN GAMMA-GLOBULIN METABOLISM AND LOW SERUM GAMMA-GLOBULIN IN GERMFREE MICE.

1964 • 83 citations

Studies on the immunoglobulin-G Fc-fragment receptor from neonatal rat small intestine

1980 • 83 citations

Interference by human and bovine serum and serum protein fractions with the absorption of antibodies by suckling rats and mice

1958 • 83 citations

Catabolism of the Murine IgGl Molecule: Evidence that Both CH2‐CH3 Domain Interfaces are Required for Persistence of IgGl in the Circulation of Mice

1994 • 71 citations

Identification of the sites of IgG catabolism in the rat

1982 • 69 citations

Prenatal and postnatal transmission of passive immunity to young rats

1955 • 69 citations

Sequential Changes in the Antimicrobial Protein Concentrations in Human Milk during Lactation and Its Relevance to Banked Human Milk

1985 • 68 citations

Metabolism of Tac (IL2Ralpha): physiology of cell surface shedding and renal catabolism, and suppression of catabolism by antibody binding.

1996 • 66 citations

Cell Biology of Intracellular Protein Trafficking

1990 • 64 citations

IgG receptors on the embryonic chick yolk sac.

1987 • 63 citations

The Selective Transport of Antibodies from the Yolk Sac to the Circulation of the Chick

1956 • 60 citations

Effects of receptor dimerization on the interaction between the class I major histocompatibility complex-related Fc receptor and IgG.

1995 • 59 citations

Receptor‐Mediated Transport of IgG Across the Intestinal Epithelium of the Neonatal Rat

1982 • 58 citations

Immunoglobulin G binding sites on the human foetal intestine: a possible mechanism for the passive transfer of immunity from mother to infant.

1993 • 56 citations

Maternofoetal Transmission of Immunoglobulins

1977 • 55 citations

Interstitial Fluid Concentrations of Albumin and Immunoglobulin G in Normal Men

1974 • 54 citations

Structural and phylogenetic analysis of the MHC class I-like Fc receptor gene.

1995 • 53 citations

Relationship Between γ-Globulin Metabolism and Low Serum γ-Globulin in Germfree Mice

1964 • 53 citations

THE METABOLISM OF NORMAL PLASMA PROTEINS AND GAMMA-MYELOMA PROTEIN IN MICE BEARING PLASMA-CELL TUMORS

1961 • 51 citations

Tissue-specific and cell surface expression of human major histocompatibility complex class I heavy (HLA-B7) and light (beta 2-microglobulin) chain genes in transgenic mice.

1988 • 51 citations

β2-microglobulin co-distributes with the heavy chain of the intestinal igg-fc receptor throughout the transepithelial transport pathway of the neonatal rat

1995 • 50 citations

The transmission of homologous serum proteins to the foetus and to the amniotic fluid in the rhesus monkey

1960 • 49 citations

Studies on the catabolism of gamma- G subunits and chains.

1965 • 48 citations

The absorption of ¹²⁵I‐labelled immunoglobulin G by different regions of the gut in young rats

1974 • 45 citations

Identification of fibroblasts as a major site of albumin catabolism in peripheral tissues.

1986 • 44 citations

The route of antibodies passing from the maternal to the foetal circulation in rabbits

1949 • 44 citations

The transmission of antibodies and normal γ -globulins across the young mouse gut

1964 • 41 citations

Interstitial Fluid Concentrations of Albumin and Immunoglobulin G in Normal Men

1974 • 41 citations

Selection of antitoxins by the foetal membranes of rabbits

1954 • 40 citations

Studies on the Catabolism of γG Subunits and Chains

1965 • 38 citations

The passage into the embryonic yolk‐sac cavity of maternal plasma proteins in rabbits

1949 • 37 citations

EVIDENCE FOR SPECIES' DIFFERENCES IN THE EFFECT OF SERUM γ-GLOBULIN CONCENTRATION ON γ-GLOBULIN CATABOLISM

1964 • 35 citations

Intravascular metabolism of normal and mutant mouse immunoglobulin molecules

1990 • 33 citations

Studies on Sterility and Prenatal Mortality in Wild Rabbits

1948 • 31 citations

The absorption of antibody from immune sera and from mixtures of sera by the gut of the young rat

1958 • 30 citations

The transfer of immune complexes from the lumen of the small intestine to the bloodstream in sucking rats.

1984 • 29 citations

Protein selection in the yolk-sac splanchnopleur of the rabbit the total uptake estimated as loss from the uterus

1958 • 28 citations

Immunoglobulin levels in serum and colostral whey of protein-metabolisable energy restricted beef cows

1981 • 24 citations

GAMMA GLOBULIN TURNOVER IN RABBITS BEFORE AND DURING HYPERIMMUNIZATION

1964 • 23 citations

Immunoglobulin G Receptors of Intestinal Brush Borders from Neonatal Rats

1983 • 22 citations

Maternofoetal Transfer of γ G Immunoglobulins

1967 • 22 citations

Resemblances between Passive Anaphylactic Sensitization and Transmission of Passive Immunity

1963 • 21 citations

The relative transmission of natural and pepsin-refined homologous antitoxin from the uterine cavity to the foetal circulation in the rabbit

1959 • 20 citations

The effects of heterologous sera on the uptake of rabbit antibody from the gut of young mice

1958 • 16 citations

The effect of extracorporeal antibody removal on antibody synthesis and catabolism in immunized rabbits.

1985 • 15 citations

Appearance of IgG and IgA antibodies in human bile after tetanus toxoid immunization.

1989 • 14 citations

Serum and Secretory Immunoglobulin Levels in Preleukaemic AKR Mice and Three Other Mouse Strains

1979 • 14 citations

Studies on Sterility and Prenatal Mortality in Wild Rabbits

1947 • 14 citations

The behaviour of different types of homologous and heterologous diphtheria antitoxin when administered to pregnant guinea-pigs.

1948 • 5 citations