Neurotrophin‐4 is up‐regulated in ragged‐red fibers associated with pathogenic mitochondrial DNA mutations

Muscle Fiber Types: How Many and What Kind?

1970 • 2,152 citations

Mammalian neurotrophin-4: structure, chromosomal localization, tissue distribution, and receptor specificity.

1992 • 633 citations

Neurotrophins promote motor neuron survival and are present in embryonic limb bud

1993 • 619 citations

Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells

1993 • 525 citations

Mitochondrial DNA mutations and pathogenesis.

1997 • 427 citations

Human trks: molecular cloning, tissue distribution, and expression of extracellular domain immunoadhesins

1995 • 381 citations

Muscle-Derived Neurotrophin-4 as an Activity-Dependent Trophic Signal for Adult Motor Neurons

1995 • 377 citations

The trk B tyrosine protein kinase is a receptor for neurotrophin-4

1992 • 326 citations

Neurotrophin and neurotrophin receptors in vascular smooth muscle cells. Regulation of expression in response to injury.

1995 • 280 citations

Two novel pathogenic mitochondrial DNA mutations affecting organelle number and protein synthesis. Is the tRNA(Leu(UUR)) gene an etiologic hot spot?

1993 • 219 citations

Neurotrophin-3 prevents the death of adult central noradrenergic neurons in vivo

1994 • 212 citations

Expression of neurotrophins in skeletal muscle: Quantitative comparison and significance for motoneuron survival and maintenance of function

1995 • 192 citations

[43]Cytochemistry and immunocytochemistry of mitochondria in tissue sections

1996 • 191 citations

Neurotrophin 4/5 is a trophic factor for mammalian facial motor neurons.

1994 • 120 citations

Morphological observations in skeletal muscle from patients with a mitochondrial myopathy

1987 • 59 citations

Single muscle fiber analysis of mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke‐like episodes (MELAS)

1994 • 51 citations

Immunocytochemical demonstration of cytochrome c oxidase with an immunoperoxidase method: a specific stain for mitochondria in formalin-fixed and paraffin-embedded human tissues.

1985 • 31 citations

Rapid nonradioactive in situ hybridization for interleukin-2 mRNA with riboprobes generated using the polymerase chain reaction

1994 • 17 citations

Localization and amount of myoglobin and myoglobin mRNA in ragged-red fiber of patients with mitochondrial encephalomyopathy

1996 • 8 citations