Studies of human, mouse and yeast homologues indicate a mitochondrial function for frataxin

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1993 • 6,762 citations

Life with 6000 Genes

1996 • 4,125 citations

Free radicals, antioxidants, and human disease: curiosity, cause, or consequence?

1994 • 3,002 citations

Friedreich's Ataxia: Autosomal Recessive Disease Caused by an Intronic GAA Triplet Repeat Expansion

1996 • 2,667 citations

New heterologous modules for classical or PCR‐based gene disruptions in Saccharomyces cerevisiae

1994 • 2,554 citations

A knowledge base for predicting protein localization sites in eukaryotic cells

1992 • 1,518 citations

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

1995 • 1,424 citations

[19] Targeting, disruption, replacement, and allele rescue: Integrative DNA transformation in yeast

1991 • 1,369 citations

Common Principles of Protein Translocation Across Membranes

1996 • 1,081 citations

Clinical and Genetic Abnormalities in Patients with Friedreich's Ataxia

1996 • 1,038 citations

Regulation of Mitochondrial Iron Accumulation by Yfh1p, a Putative Homolog of Frataxin

1997 • 914 citations

FRIEDREICH'S ATAXIA: A CLINICAL AND GENETIC STUDY OF 90 FAMILIES WITH AN ANALYSIS OF EARLY DIAGNOSTIC CRITERIA AND INTRAFAMILIAL CLUSTERING OF CLINICAL FEATURES

1981 • 903 citations

Ataxia with isolated vitamin E deficiency is caused by mutations in the α–tocopherol transfer protein

1995 • 561 citations

High efficiency gene transfer into mammalian cells

1984 • 498 citations

Mitochondrial DNA mutations in human degenerative diseases and aging

1995 • 224 citations

Friedreich's ataxia protein: phylogenetic evidence for mitochondrial dysfunction

1996 • 156 citations

The mouse homologue of the human acidic ribosomal phosphoprotein PO: a highly conserved polypeptide that is under translational control

1989 • 91 citations

Incidence of Friedreich ataxia in Italy estimated from consanguineous marriages.

1983 • 79 citations

The Friedreich's ataxia gene encodes a novel phosphatidylinositol–4–phosphate 5–kinase

1996 • 72 citations

Friedreich's ataxia in Western Norway

1975 • 41 citations

In situ hybridization of nucleic acid probes to cellular rna

1995 • 38 citations

Friedreich's ataxia: a defect in signal transduction?

1995 • 25 citations

A eukaryotic expression vector for the study of nuclear localization signals

1994 • 8 citations