Retrovirus Vectors: Promise and Reality

Altering the Genome by Homologous Recombination

1989 • 2,021 citations

Improved retroviral vectors for gene transfer and expression.

1989 • 1,997 citations

Prospects for Human Gene Therapy

1984 • 548 citations

Progress Toward Human Gene Therapy

1989 • 484 citations

Genetic Engineering of Livestock

1989 • 437 citations

Lineage-specific expression of a human β-globin gene in murine bone marrow transplant recipients reconstituted with retrovirus-transduced stem cells

1988 • 341 citations

Germline Transmission of Exogenous Genes in the Chicken

1989 • 195 citations

Improved gene expression upon transfer of the adenosine deaminase minigene outside the transcriptional unit of a retroviral vector.

1989 • 192 citations

Transgenic chickens: Insertion of retroviral genes into the chicken germ line

1987 • 182 citations

A majority of mice show long-term expression of a human beta-globin gene after retrovirus transfer into hematopoietic stem cells.

1989 • 153 citations

New retrovirus helper cells with almost no nucleotide sequence homology to retrovirus vectors

1989 • 128 citations

Expression of human adenosine deaminase in mice reconstituted with retrovirus-transduced hematopoietic stem cells.

1990 • 105 citations

A promoterless retroviral vector indicates that there are sequences in U3 required for 3' RNA processing.

1987 • 100 citations

Identification of cellular promoters by using a retrovirus promoter trap

1989 • 74 citations

Analysis of mammalian cell genetic regulation in situ by using retrovirus-derived "portable exons" carrying the Escherichia coli lacZ gene.

1989 • 71 citations

Replication-defective vectors of reticuloendotheliosis virus transduce exogenous genes into somatic stem cells of the unincubated chicken embryo

1989 • 57 citations