Autoantibody to Thioredoxin Reductase in an Ovarian Cancer Patient

Selenocysteine, identified as the penultimate C-terminal residue in human T-cell thioredoxin reductase, corresponds to TGA in the human placental gene.

1996 • 471 citations

Detection of antibodies against the cellular protein p53 in sera from patients with breast cancer

1982 • 448 citations

A Novel Kinase Cascade Mediated by Mitogen-activated Protein Kinase Kinase 6 and MKK3

1996 • 443 citations

Neuronal antinuclear antibody in sensory neuronopathy from lung cancer

1985 • 353 citations

Thioredoxin and thioredoxin reductase gene expression in human tumors and cell lines, and the effects of serum stimulation and hypoxia.

1996 • 309 citations

Development of antibodies against p53 in lung cancer patients appears to be dependent on the type of p53 mutation.

1992 • 299 citations

Immune response to p53 is dependent upon p53/HSP70 complexes in breast cancers.

1992 • 281 citations

Cellular levels of thioredoxin associated with drug sensitivity to cisplatin, mitomycin C, doxorubicin, and etoposide.

1995 • 240 citations

Cloning and sequencing of a human thioredoxin reductase

1995 • 211 citations

Analysis of p53 antibodies in patients with various cancers define B-cell epitopes of human p53: distribution on primary structure and exposure on protein surface.

1993 • 173 citations

Immunohistochemical localization of thioredoxin and thioredoxin reductase in adult rats.

1985 • 158 citations

Analysis of the anti-p53 antibody response in cancer patients.

1993 • 134 citations

Nucleolar antigens and autoantibodies in hepatocellular carcinoma and other malignancies.

1992 • 127 citations

NK-lysin, a Disulfide-containing Effector Peptide of T-lymphocytes, Is Reduced and Inactivated by Human Thioredoxin Reductase

1996 • 127 citations

Redox Signaling and the Control of Cell Growth and Death

1996 • 120 citations

A Cell-Cycle Nuclear Autoantigen Containing Wd-40 Motifs Expressed Mainly in S and G2-Phase Cells

1995 • 88 citations

A mutation in a thioredoxin reductase homolog suppresses p53-induced growth inhibition in the fission yeastSchizosaccharomyces pombe

1996 • 71 citations

Human autoantibodies to poly(adenosine diphosphate-ribose) polymerase.

1987 • 60 citations

The heterogeneity of anticentromere antibodies in immunoblotting analysis.

1990 • 53 citations

Human Thioredoxin Reductase Gene Localization to Chromosomal Position 12q23–q24.1 and mRNA Distribution in Human Tissue

1996 • 40 citations

Heparin-binding properties of selenium-containing thioredoxin reductase from HeLa cells and human lung adenocarcinoma cells

1997 • 38 citations

Ultrastructural demonstration of thioredoxin and thioredoxin reductase in rat hepatocytes.

1988 • 28 citations

Synthetic compound peptide simulating antigenicity of conformation-dependent autoepitope

1994 • 23 citations

Clinical features of anti-chromo antibodies associated with anti-centromere antibodies

1996 • 22 citations

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