Food deprivation and hypothalamic neuropeptide gene expression: effects of strain background and the diabetes mutation

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Neuropeptide Y—a novel brain peptide with structural similarities to peptide YY and pancreatic polypeptide

1982 • 2,244 citations

Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice

1978 • 1,274 citations

NEUROPEPTIDE Y AND HUMAN PANCREATIC POLYPEPTIDE STIMULATE FEEDING BEHAVIOR IN RATS

1984 • 1,274 citations

Neuroreptide Y: Stimulation of feeding and drinking by injection into the paraventricular nucleus

1984 • 666 citations

Altered Expression of Hypothalamic Neuropeptide mRNAs in Food-Restricted and Food-Deprived Rats

1990 • 648 citations

Rat brain preproenkephalin mRNA. cDNA cloning, primary structure, and distribution in the central nervous system.

1984 • 540 citations

Food deprivation and ingestion induce reciprocal changes in neuropeptide Y concentrations in the paraventricular nucleus

1988 • 510 citations

Sequence and expression of the rat prodynorphin gene.

1985 • 382 citations

Thyrotropin-Releasing Hormone Precursor: Characterization in Rat Brain

1986 • 351 citations

Rat neuropeptide Y precursor gene expression. mRNA structure, tissue distribution, and regulation by glucocorticoids, cyclic AMP, and phorbol ester.

1988 • 318 citations

Increased Hypothalamic Content of Preproneuropeptide Y Messenger Ribonucleic Acid in Genetically Obese Zucker Rats and Its Regulation by Food Deprivation*

1990 • 312 citations

The influence of genetic background on expression of mutations at the diabetes locus in the mouse. I. C57BL/KsJ and C57BL/6J strains

1972 • 260 citations

Microdialysis Studies of Brain Norepinephrine, Serotonin, and Dopamine Release During Ingestive Behavior Theoretical and Clinical Implicationsa

1989 • 221 citations

Neuropeptide Y: Direct and indirect action on insulin secretion in the rat

1985 • 211 citations

SUPPRESSION OF FEEDING AND DRINKING ACTIVITY IN RATS FOLLOWING INTRAVENTRICULAR INJECTION OF THYROTROPIN RELEASING HORMONE (TRH)¹¹

1977 • 202 citations

Increased Hypothalamic Content of Preproneuropeptide-Y Messenger Ribonucleic Acid in Streptozotocin-Diabetic Rats*

1990 • 180 citations

Involvement of dynorphin and the kappa opioid receptor in feeding

1983 • 170 citations

Neuropeptide Y Stimulates the Release of Luteinizing Hormone-Releasing Hormone from Medial Basal Hypothalamus in vitro: Modulation by Ovarian Hormones

1987 • 167 citations

Somatostatin-28 encoded in a cloned cDNA obtained from a rat medullary thyroid carcinoma.

1982 • 144 citations

Neuropeptide-Y Concentration in Microdissected Hypothalamic Regions andin VitroRelease from the Medial Basal Hypothalamus-Preoptic Area of Streptozotocin-Diabetic Rats with and without Insulin Substitution Therapy*

1990 • 128 citations

Mechanisms of trans-synaptic regulation of gene expression

1987 • 125 citations

Increased Hypothalamic Neuropeptide Y Concentrations in Diabetic Rat

1988 • 120 citations

Estradiol induction of proenkephalin messenger RNA in hypothalamus: dose-response and relation to reproductive behavior in the female rat

1990 • 119 citations

Opioid-induced feeding: Localization of sensitive brain sites

1986 • 117 citations

Feeding induced by opiates injected into the paraventricular hypothalamus

1983 • 114 citations

BODY WEIGHT LOSS AS A MEASURE OF MOTIVATION IN HUNGER AND THIRST*

1969 • 104 citations

Interaction between neuropeptide Y and noradrenaline on central catecholamine neurons

1990 • 92 citations

Effect of intrahypothalamic injection of [D-Ala2,D-Leu5]enkephalin on feeding and temperature in the rat

1983 • 86 citations

Neurophysiology of feeding

1978 • 80 citations

Ultrastructural localization of neuropeptide Y and galanin immunoreactivity in the paraventricular nucleus of the hypothalamus in the rat

1988 • 73 citations

Neuropeptide Y-induced effects on hypothalamic corticotropin-releasing factor content and release are dependent on noradrenergic/adrenergic neurotransmission

1989 • 66 citations

Intraventricular administration of neuropeptide Y (NPY) induces hypotension, bradycardia and bradypnoea in the awake unrestrained male rat. Counteraction by NPY‐induced feeding behaviour

1986 • 60 citations

Increased hypothalamic neuropeptide Y concentrations in diabetic rat

1988 • 60 citations

Food deprivation and age modulate neuropeptide gene expression in the murine hypothalamus and adrenal gland

1991 • 58 citations

Neuropeptide Y in the hypothalamus: effect on corticosterone and single-unit activity

1990 • 54 citations

The effects of hypothalamics lesions in genetically diabetic mice

1970 • 51 citations

Dietary control of pathogenesis in diabetes mice

1981 • 48 citations

Peptidergic Regulation of Feeding

1985 • 47 citations

Morphometric analysis of obesity (ob/ob)- and diabetes (db/db)-associated hypothalamic neuronal degeneration in C57BL/KsJ mice

1989 • 33 citations

Diabetes-associated changes in estradiol accumulation in the aging C57BL/KsJ mouse brain

1984 • 23 citations

Cage population density and efficiency of feed utilization in inbred mice.

1968 • 10 citations

Unique alterations of neuropeptide content in median eminence, amygdala, and dorsal vagal complex of 3- and 6-week-old diabetes mutant mice

1990 • 10 citations

Regulation of liver tyrosine aminotransferase activity in inbred strains and mutant mice. II. Studies on the starvation-induced enzyme adaptation

1970 • 7 citations