Cell‐free‐synthesized interleukin‐6 (BSF‐2/IFN‐β2) exhibits hepatocyte‐stimulating activity

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

An Efficient mRNA‐Dependent Translation System from Reticulocyte Lysates

1976 • 3,994 citations

Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin

1986 • 2,137 citations

Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells.

1987 • 1,667 citations

Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs

1985 • 1,594 citations

THE PHENOMENON OF THE ACUTE PHASE RESPONSE*

1982 • 1,498 citations

Cytoplasmic dot hybridization. Simple analysis of relative mRNA levels in multiple small cell or tissue samples.

1982 • 1,333 citations

Polypeptides of the tail fibres of bacteriophage T4

1971 • 956 citations

Purification to homogeneity and characterization of human B-cell differentiation factor (BCDF or BSFp-2).

1985 • 679 citations

Cachectin/tumor necrosis factor regulates hepatic acute-phase gene expression.

1986 • 585 citations

Structure and expression of cDNA and genes for human interferon-beta-2, a distinct species inducible by growth-stimulatory cytokines.

1986 • 505 citations

Pretranslational modulation of acute phase hepatic protein synthesis by murine recombinant interleukin 1 (IL-1) and purified human IL-1.

1985 • 423 citations

Monocyte-conditioned medium, interleukin-1, and tumor necrosis factor stimulate the acute phase response in human hepatoma cells in vitro.

1986 • 398 citations

Characterization of differentiated and dedifferentiated clones from a rat hepatoma

1975 • 381 citations

Human B-cell differentiation factor defined by an anti-peptide antibody and its possible role in autoantibody production.

1987 • 363 citations

Structural analysis of the sequence coding for an inducible 26‐kDa protein in human fibroblasts

1986 • 343 citations

The interleukin-1 receptor binds the human interleukin-1 alpha precursor but not the interleukin-1 beta precursor.

1987 • 342 citations

The acute phase response to injury and infection

1985 • 332 citations

Recombinant human B cell stimulatory factor 2 (BSF‐2/IFN‐β2) regulates β‐fibrinogen and albumin mRNA levels in Fao‐9 cells

1987 • 299 citations

Human keratinocytes and monocytes release factors which regulate the synthesis of major acute phase plasma proteins in hepatic cells from man, rat, and mouse.

1984 • 225 citations

B cell growth modulating and differentiating activity of recombinant human 26-kd protein (BSF-2, HuIFN-beta 2, HPGF).

1987 • 220 citations

HEPATOCYTE‐STIMULATING FACTOR: A MONOCYTE‐DERIVED ACUTE‐PHASE REGULATORY PROTEIN

1983 • 207 citations

Human β ₂ Interferon and B-Cell Differentiation Factor BSF-2 Are Identical

1987 • 204 citations

The acute phase response of plasma protein synthesis during experimental inflammation.

1982 • 191 citations

The acute-phase response of cultured rat hepatocytes. System characterization and the effect of human cytokines

1984 • 166 citations

Rat alpha 1-acid glycoprotein mRNA. Cloning of double-stranded cDNA and kinetics of induction of mRNA levels following acute inflammation.

1981 • 139 citations

Regulation of Class III Major Histocompatibility Complex Gene Products by Interleukin-1

1986 • 125 citations

The α macroglobulins of rat serum

1976 • 112 citations

Molecular cloning of cDNA sequences for rat alpha 2-macroglobulin and measurement of its transcription during experimental inflammation.

1985 • 97 citations

Changes in the blood level and affinity to concanavalin A of rat plasma glycoproteins during acute inflammation and hepatoma growth

1982 • 84 citations

A rat serum glycoprotein whose synthesis rate increases greatly during inflammation.

1979 • 74 citations

Interferon β2 as a promoter of growth and differentiation of B cells

1987 • 74 citations

Toxicity of d-galactosamine for rat hepatocytes in monolayer culture

1985 • 72 citations

The Biosynthesis of Acute‐Phase Proteins in Primary Cultures of Rat Hepatocytes

1983 • 71 citations

Purification and immunological determination of α2-macroglobulin in serum from injured rats

1981 • 68 citations

Murine interleukin 1 stimulates α₂‐macroglobulin synthesis in rat hepatocyte primary cultures

1985 • 59 citations

Biosynthesis of human C-reactive protein in cultured hepatoma cells is induced by a monocyte factor(s) other than interleukin-1.

1987 • 58 citations

Limited effects of recombinant human and murine interleukin 1 and tumour necrosis factor on production of acute phase proteins by cultured rat hepatocytes.

1987 • 58 citations

The acute-phase induction of alpha 2-macroglobulin in rat hepatocyte primary cultures: action of a hepatocyte-stimulating factor, triiodothyronine and dexamethasone.

1986 • 46 citations

Cell‐free synthesis of rat α₂‐macroglobulin and induction of its mRNA during experimental inflammation

1983 • 45 citations

The Effect of Heparin on Diamine Oxidase and Lipoprotein Lipase in Human Lymph and Blood Plasma

1968 • 43 citations

The inflammation mediators interleukin 1 and hepatocyte-stimulating factor are differently regulated in human monocytes

1987 • 43 citations

Discrimination of hepatocyte‐stimulating activity from human recombinant tumor necrosis factor α

1987 • 38 citations

Proteolytic processing of presecretory proteins is required for development of biological activities in pancreatic exocrine proteins.

1983 • 38 citations

Regulation of Human Gamma-Interferon and Beta-Interferon Gene Expression in PHA-Activated Lymphocytes

1986 • 36 citations

De novo biosynthesis of an enzymatically active precursor form of bovine pancreatic RNase.

1979 • 27 citations

Isolation of hepatocyte stimulating factor from human monocytes

1987 • 18 citations

Biosynthesis and secretion of α₁ acute‐phase globulin in primary cultures of rat hepatcytes

1985 • 17 citations

Detection of alpha-amylase activity in unprocessed preamylase produced in the cell-free translation of porcine pancreatic RNA.

1981 • 15 citations

Interaction of mature, unglycosylated and cell‐free synthesized rat α1‐proteinase inhibitor with elastase

1983 • 7 citations