Characterization and biological properties of a hepatitis B virus isolated from a patient without hepatitis B virus serologic markers

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase

1988 • 4,259 citations

The hepatitis B virus

1985 • 1,219 citations

Typing Hepatitis B Virus by Homology in Nucleotide Sequence: Comparison of Surface Antigen Subtypes

1988 • 1,057 citations

Integration of Hepatitis B Virus DNA into the Genome of Liver Cells in Chronic Liver Disease and Hepatocellular Carcinoma

1981 • 715 citations

Identification and chemical synthesis of a host cell receptor binding site on hepatitis B virus

1986 • 523 citations

RUBELLA VACCINATION

1973 • 502 citations

Hepatitis B Virus DNA in Patients with Chronic Liver Disease and Negative Tests for Hepatitis B Surface Antigen

1985 • 466 citations

Sequence homology between retroviral reverse transcriptase and putative polymerases of hepatitis B virus and cauliflower mosaic virus

1983 • 464 citations

Tbe complete nudeotide sequences of the cloned hepatitis B vims DNA; subtype adr and adw

1983 • 426 citations

Regulatory pathways governing HIV-1 replication

1989 • 401 citations

Antibody production to the nucleocapsid and envelope of the hepatitis B virus primed by a single synthetic T cell site

1987 • 319 citations

TRANSMISSION OF HEPATITIS B FROM HEPATITIS-B-SERONEGATIVE SUBJECTS

1988 • 316 citations

Detection of serum hepatitis B virus DNA in patients with chronic hepatitis using the polymerase chain reaction assay.

1989 • 305 citations

Nonresponsiveness to Hepatitis B Vaccine in Health Care Workers

1986 • 218 citations

The amino-terminal domain of the hepadnaviral P-gene encodes the terminal protein (genome-linked protein) believed to prime reverse transcription.

1988 • 198 citations

Human T cell response to the surface antigen of hepatitis B virus (HBsAg). Endosomal and nonendosomal processing pathways are accessible to both endogenous and exogenous antigen.

1988 • 180 citations

Location and Chemical Synthesis of a Pre-S Gene Coded Immunodominant Epitope of Hepatitis B Virus

1984 • 170 citations

Viral persistence

1989 • 148 citations

Hepatocellular carcinoma in woodchuck hepatitis virus-infected woodchucks: Presence of viral DNA in tumor tissue from chronic carriers and animals serologically recovered from acute infections

1989 • 147 citations

Mutation rate of the hepadnavirus genome

1989 • 139 citations

Compact organization of the hepatitis B virus genome

1989 • 112 citations

Identification and transmission of hepatitis B virus-related variants.

1986 • 99 citations

Structure of hepatitis B surface antigen. Correlation of subtype with amino acid sequence and location of the carbohydrate moiety.

1982 • 91 citations

HBsAG POSITIVE REACTIVITY IN MAN NOT DUE TO HEPATITIS B VIRUS

1987 • 88 citations

Interferon inhibits hepatitis B virus replication in a stable expression system of transfected viral DNA

1989 • 76 citations

Hepatitis B Viral Nucleotide Sequences in Non-A, Non-B or Hepatitis B Virus-Related Chronic Liver Disease

1984 • 75 citations

The loss of subtypic determinants in alleles, d/y or w/r, on hepatitis B surface antigen

1989 • 60 citations

Rapid identification of low level hepatitis B-related viral genome in serum.

1989 • 55 citations

Latent hepatitis B virus infection with full‐length viral genome in a patient serologically immune to hepatitis B virus infection

1988 • 44 citations

Prediction of terminal protein and ribonuclease H domains in the gene P product of hepadnaviruses

1989 • 38 citations

Structural analysis of hepatitis B surface antigen by monoclonal antibodies.

1985 • 34 citations

Hepatitis B viral antigenic structure: signature analysis by monoclonal radioimmunoassays.

1984 • 32 citations

HBcAg expressed on the surface of circulating dane particles in patients with hepatitis B virus infection without evidence of anti-HBc formation

1989 • 28 citations

Improved detection of hepatitis B surface antigen (HBsAg) in blood donors by monoclonal radioimmunoassay

1985 • 28 citations