Mechanism of Inhibition of Glutamine Synthetase by Methionine Sulphoximine

THE COLORIMETRIC DETERMINATION OF PHOSPHORUS

1925 • 19,115 citations

The Determination of Enzyme Dissociation Constants

1934 • 11,865 citations

A modified ninhydrin colorimetric analysis for amino acids

1957 • 2,207 citations

THE CHROMATOGRAPHIC IDENTIFICATION OF SOME BIOLOGICALLY IMPORTANT PHOSPHATE ESTERS

1951 • 745 citations

Iontophoretic studies of neurones in the mammalian cerebral cortex

1963 • 659 citations

Mechanism of inhibition of glutamine synthetase by methionine sulfoximine

1969 • 328 citations

Determination of D- and L-Amino Acids by Ion Exchange Chromatography as L-D and L-L Dipeptides

1968 • 275 citations

[115] Characterization of phosphorus compounds by acid lability

1957 • 266 citations

Identification of L-methionine S-sulfoximine as the diastereoisomer of L-methionine SR-sulfoximine that inhibits glutamine synthetase

1969 • 161 citations

Studies on the Mechanism of Glutamine Synthesis: Evidence for the Formation of Enzyme-bound Activated Glutamic Acid

1962 • 161 citations

Inhibition of glutamine synthetase by methionine sulfoximine. Studies On Methionine sulfoximine phosphate

1969 • 158 citations

Phosphorylation of methionine sulfoximine by glutamine synthetase.

1968 • 156 citations

EFFECT OF AN INHIBITOR OF GLUTAMINE SYNTHESIS (METHIONINE SULFOXIMINE) ON AMMONIA TOXICITY AND METABOLISM.

1964 • 146 citations

Glutamine Synthetase of Rat Cerebral Cortex: Intracellular Distribution and Structural Latency

1962 • 119 citations

The inhibition in vivo of cerebral glutamine synthetase and glutamine transferase by the convulsant methionine sulfoximine

1965 • 111 citations

Diet and Canine Hysteria: Experimental Production

1946 • 110 citations

Binding of Adenosine Triphosphate and Adenosine Diphosphate by Glutamine Synthetase^*

1966 • 106 citations

NERVE ENDINGS IN METHIONINE SULPHOXIMINE CONVULSANT RATS, A NEUROCHEMICAL AND ULTRASTRUCTURAL STUDY*

1967 • 105 citations

THE FORMATION, RESOLUTION, AND OPTICAL PROPERTIES OF THE DIASTEREOISOMERIC SULFOXIDES DERIVED FROM l-METHIONINE

1947 • 104 citations

Methionine Sulphoximine and some Enzyme Systems involving Glutamine

1952 • 100 citations

Identification of L-Methionine- S -Sulfoximine as the Convulsant Isomer of Methionine Sulfoximine

1970 • 92 citations

Computer analysis of the active site of glutamine synthetase

1970 • 89 citations

METHIONINE STUDIES

1939 • 88 citations

Direct Oxygen Transfer in Enzymic Syntheses Coupled to Adenosine Triphosphate Degradation¹

1956 • 82 citations

GLUTAMIC ACID AND GLUTAMINE METABOLISM IN CEREBRAL CORTEX AFTER SEIZURES INDUCED BY METHIONINE SULPHOXIMINE

1959 • 75 citations

Preparation and characterization of sheep brain glutamine synthetase

1969 • 69 citations

TRANSFER OF OXYGEN IN THE GLUTAMINE SYNTHETASE REACTION

1956 • 67 citations

The nature of the inhibition in vitro of cerebral glutamine synthetase by the convulsant, methionine sulfoximine

1963 • 59 citations

ENZYMATIC SYNTHESIS OF D-GLUTAMINE AND RELATED HYDROXAMIC ACIDS

1953 • 55 citations

The duration of the inhibition of glutamine synthetase by methionine sulfoximine

1968 • 50 citations

Methionine sulfoximine seizures. 8. The dissociation of the convulsant and glutamine synthetase inhibitory effects.

1968 • 50 citations

Action of nitrogen trichloride on certain proteins II. Synthesis of methionine sulphoximine and other sulphoximines

1951 • 46 citations

Stereospecific Synthesis of α-Methyl-L-glutamine by Glutamine Synthetase^*

1965 • 44 citations

1-Amino-1,3-dicarboxycyclohexane (cycloglutamic acid). New glutamic acid analog and a substrate of glutamine synthetase

1970 • 43 citations

Enzymatic Synthesis of β-Aminoglutaramic Acid (β-Glutamine) by Glutamine Synthetase: Evidence for the Utilization of β-Aminoglutarylphosphate^*

1964 • 42 citations

Effects of methionine sulfoximine on levels of free amino acids and related substances in brain

1964 • 42 citations

The Methionine Sulfoximine Syndrome in the Cat

1962 • 38 citations

Activity of Glutamine Synthetase toward the Optical Isomers of α-Aminoadipic Acid^*

1966 • 37 citations

Activity of Glutamine Synthetase toward threo-γ-Methyl-L-glutamic Acid and the Isomers of γ-Hydroxyglumatic Acid

1966 • 34 citations

Subunit structure of ovine brain glutamine synthetase

1969 • 31 citations

DIVISION OF BIOPHYSICS: ELECTRON MICROSCOPY OF ENZYMES*,†

1968 • 30 citations

NITROGEN TRICHLORIDE AND CANINE HYSTERIA

1947 • 28 citations

Stereospecific Activity of Glutamine Synthetase toward threo-β-Methyl-D-glutamic acid^*

1966 • 25 citations

Inactivation of cerebral glutamine synthetase by dl-methionine-dl-sulfoximine

1967 • 25 citations

Synthesis of d-β-Glutamine from β-Glutamic Acid by Glutamine Synthetase

1965 • 22 citations

Stickstoffmetabolismus des Gehirns und der Leber bei Ratten nach einer Applikation von Methioninsulfoximin

1959 • 20 citations

Action of Nitrogen Trichloride on Proteins : Production of Toxic Derivative

1948 • 15 citations

Dissociation of native octameric brain glutamine synthetase to a tetramer by treatment with N-acetylimidazole

1970 • 10 citations

The inhibition of cerebral glutamine synthetase by structural analogs of the convulsant dl-methionine sulfoximine

1966 • 6 citations

Behavioral and convulsive phenomena induced in the cat by methionine sulfoximine

1965 • 6 citations

Cornell University Medical College

1949 • 1 citations