Substrate and Product Binding Sites of Yeast Fatty Acid Synthase. Stoichiometry and Binding Kinetics of Wild-Type and in vitro Mutated Enzymes

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector

1987 • 1,181 citations

FATTY ACID SYNTHESIS AND ITS REGULATION

1983 • 1,007 citations

A family of yeast expression vectors containing the phage f1 intergenic region1

1987 • 514 citations

Negative cooperativity in enzyme action. Binding of diphosphopyridine nucleotide to glyceraldehyde-3-phosphate dehydrogenase

1968 • 456 citations

Efficient oligonucleotide-directed construction of mutations in expression vectors by the gapped duplex DNA method using alternating selectable markers

1989 • 321 citations

Chemical Nature of the Catalytic Sites in Glyceraldehyde-3-Phosphate Dehydrogenase

1963 • 245 citations

On the Structure of Fatty Acid Synthetase of Yeast

1980 • 164 citations

Replication in Saccharomyces cerevisiae of plasmid pBR313 carrying DNA from the yeast trpl region

1979 • 141 citations

The pentafunctional FAS1 gene of yeast: its nucleotide sequence and order of the catalytic domains

1986 • 126 citations

Molecular basis of negative co-operativity in rabbit muscle glyceraldehyde-3-phosphate dehydrogenase

1974 • 95 citations

Fatty acid biosynthesis in yeast

1978 • 79 citations

Gene Linkage and Gene‐Enzyme Relations in the Fatty‐Acid‐Synthetase System of Saccharomyces cerevisiae

1972 • 59 citations

On the question of half- or full-site reactivity of animal fatty acid synthetase.

1984 • 55 citations

Die Malonyl‐Bindungsstellen des Fettsäuresynthetase‐Komplexes aus Hefe

1970 • 52 citations

Reaction of Yeast Fatty Acid Synthetase with Iodoacetamide

1977 • 51 citations

Yeast fatty acid synthase: structure to function relationship

1985 • 46 citations

Reaction of Yeast Fatty Acid Synthetase with Iodoacetamide

1977 • 44 citations

Molecular cloning of the yeast fatty acid synthetase genes, FAS1 and FAS2: Illustrating the structure of the FAS1 cluster gene by transcript mapping and transformation studies

1984 • 42 citations

Differential proteolytic sensitivity of yeast fatty acid synthetase subunits α and β contributing to a balanced ratio of both fatty acid synthetase components

1992 • 41 citations

The yeast fatty acid synthetase. Structure-function relationship and the role of the active cysteine-SH and pantetheine-SH.

1981 • 40 citations

Mammalian fatty acid synthetase is a structurally and functionally symmetrical dimer

1985 • 39 citations

Participation of covalently linked fatty acryl coenzyme A products in the action of yeast fatty acid synthetase

1972 • 39 citations

Genetic control of fatty acid synthetase biosynthesis and structure in lower fungi

1987 • 37 citations

Identity of Malonyl and Palmitoyl Transferase of Fatty Acid Synthetase from Yeast. 2. A Comparison of Active-Site Peptides

1979 • 34 citations

Charakterisierung der Acetyltransferase in der Fettsaäresynthetase aus Hefe

1972 • 32 citations

The Palmityl Binding Sites of Fatty Acid Synthetase from Yeast

1977 • 31 citations

Affinity labeling of fatty acid synthetase from lactating rat mammary gland with S-(4-bromo-2,3-dioxobutyl)-CoA: Evidence for a “half-of-the-sites” catalytic mechanism

1979 • 27 citations

Elementary steps in the reaction mechanism of chicken liver fatty acid synthase: acetylation-deacetylation

1983 • 27 citations

Elementary steps in the reaction mechanism of chicken liver fatty acid synthase. Acylation of specific binding sites.

1985 • 21 citations

Differential Activities and Intramolecular Location of Fatty Acid Synthase and 6-Methylsalicylic Acid Synthase Component Enzymes

1994 • 20 citations

Reaction of chloroacetyl‐CoA with rabbit fatty acid synthase

1982 • 19 citations

Identity of Malonyl and Palmitoyl Transferase of Fatty Acid Synthetase from Yeast. 1. Functional Interrelationships between the Acyl Transferases

1979 • 16 citations

Biosynthese und Struktur des Fetts�uresynthetase-Komplexes der Hefe

1977 • 16 citations

Kinetic and structural investigation of acyl-binding sites on avian fatty acid synthase.

1983 • 15 citations

The yeast fatty acid synthase. Pathway for transfer of the acetyl group from coenzyme A to the Cys-SH of the condensation site.

1990 • 15 citations