Cyclic AMP phosphodiesterases in human lymphocytes

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Cytokine patterns of immunologically mediated tissue damage.

1992 • 285 citations

Evidence that insulin and isoprenaline activate the cGMP-inhibited low-Km cAMP phosphodiesterase in rat fat cells by phosphorylation.

1990 • 174 citations

Molecular cloning of the rat adipocyte hormone-sensitive cyclic GMP-inhibited cyclic nucleotide phosphodiesterase.

1993 • 137 citations

Characterization and selective inhibition of cyclic nucleotide phosphodiesterase isozymes in canine tracheal smooth muscle.

1990 • 131 citations

Multiple high-affinity cAMP-phosphodiesterases in human T-lymphocytes

1991 • 130 citations

Cyclic AMP metabolism in cholesterol-rich platelets.

1977 • 128 citations

Hormone-sensitive cyclic GMP-inhibited cyclic AMP phosphodiesterase in rat adipocytes. Regulation of insulin- and cAMP-dependent activation by phosphorylation

1991 • 119 citations

Evidence for the key role of the adipocyte cGMP-inhibited cAMP phosphodiesterase in the antilipolytic action of insulin

1995 • 116 citations

Salbutamol Up-regulates PDE4 Activity and Induces a Heterologous Desensitization of U937 Cells to Prostaglandin E2

1995 • 92 citations

The platelet insulin receptor: Detection, partial characterization, and search for a function

1988 • 80 citations

Single-step affinity purification, partial structure and properties of human platelet cGMP inhibited cAMP phosphodiesterase

1994 • 46 citations

Human platelet cGI-PDE: expression in yeast and localization of the catalytic domain by deletion mutagenesis

1996 • 45 citations

Decreased sensitivity to cAMP in the in vitro generation of memory splenic cytotoxic T-lymphocytes from aged mice: role of phosphodiesterase.

1993 • 12 citations