Inhaled Nitric Oxide, Almitrine Infusion, or Their Coadministration as a Treatment of Severe Hypoxemic Focal Lung Lesions

An Expanded Definition of the Adult Respiratory Distress Syndrome

1988 • 2,636 citations

Ventilator-induced Lung Injury

1998 • 2,270 citations

Inhaled Nitric Oxide for the Adult Respiratory Distress Syndrome

1993 • 1,811 citations

Estimation of the Box Correction for Degrees of Freedom from Sample Data in Randomized Block and Split-Plot Designs

1976 • 1,529 citations

Multiple-Organ Failure

1985 • 1,314 citations

A simplified acute physiology score for ICU patients

1984 • 1,244 citations

Inhaled nitric oxide. A selective pulmonary vasodilator reversing hypoxic pulmonary vasoconstriction.

1991 • 1,134 citations

Inhaled Nitric Oxide Selectively Reverses Human Hypoxic Pulmonary Vasoconstriction without Causing Systemic Vasodilation

1993 • 459 citations

Ventilation/Blood Flow and Gas Exchange.

1978 • 316 citations

Prolonged Inhalation of Low Concentrations of Nitric Oxide in Patients with Severe Adult Respiratory Distress Syndrome

1994 • 282 citations

Pulmonary Pathophysiology: The Essentials

1982 • 282 citations

Efficacy of Inhaled Nitric Oxide in Patients With Severe ARDS

1995 • 258 citations

Diagnosis of Nosocomial Pneumonia in Mechanically Ventilated Patients: Comparison of a Plugged Telescoping Catheter with the Protected Specimen Brush

1991 • 241 citations

Histologic aspects of pulmonary barotrauma in critically ill patients with acute respiratory failure

1993 • 204 citations

Additive effect on gas exchange of inhaled nitric oxide and intravenous almitrine bismesylate in the adult respiratory distress syndrome

1994 • 160 citations

Factors influencing cardiopulmonary effects of inhaled nitric oxide in acute respiratory failure.

1995 • 156 citations

Role of hypoxic pulmonary vasoconstriction in pulmonary gas exchange and blood flow distribution

1994 • 156 citations

Role of hypoxic pulmonary vasoconstriction in pulmonary gas exchange and blood flow distribution

1994 • 155 citations

Effectiveness of Nitric Oxide Inhalation in Septic ARDS

1996 • 131 citations

Dose-Response Curves of Inhaled Nitric Oxide with and without Intravenous Almitrine in Nitric Oxide-responding Patients with Acute Respiratory Distress Syndrome

1995 • 111 citations

Additive beneficial effects of the prone position, nitric oxide, and almitrine bismesylate on gas exchange and oxygen transport in acute respiratory distress syndrome

1997 • 108 citations

Endogenous endothelium-derived relaxing factor opposes hypoxic pulmonary vasoconstriction and supports blood flow to hypoxic alveoli in anesthetized rabbits.

1992 • 104 citations

Blockade of acute hypoxic pulmonary hypertension by endotoxin.

1974 • 76 citations

Decreased Pulmonary Vasoreactivity in an Animal Model of ChronicPseudomonasPneumonia

1990 • 56 citations

Interest of a Therapeutic Optimization Strategy in Severe ARDS

1997 • 54 citations

Enhancement of hypoxic pulmonary vasoconstriction by almitrine in the dog.

1983 • 54 citations

A Comparative Study of the Effects of Almitrine Bismesylate and Lateral Position during Unilateral Bacterial Pneumonia with Severe Hypoxemia

1992 • 41 citations

Damage and repair of lung connective tissue in rats exposed to toxic levels of oxygen.

1987 • 39 citations

Restored Hypoxic Pulmonary Vasoconstriction by Peripheral Chemoreceptor Agonists in Dogs

1990 • 33 citations

High-dose Almitrine Bismesylate Inhibits Hypoxic Pulmonary Vasoconstriction in Closed-chest Dogs

1987 • 32 citations

Almitrine in Acute Respiratory Failure

1987 • 32 citations

Low-Dose Almitrine Bismesylate Enhances Hypoxic Pulmonary Vasoconstriction in Closed-Chest Dogs

1990 • 26 citations

Almitrine mimics hypoxic vasoconstriction in isolated rat lungs

1992 • 22 citations

Effect of sodium nitroprusside and diethylcarbamazine on hypoxic pulmonary vasoconstriction and regional distribution of pulmonary blood flow in experimental pneumonia.

1996 • 12 citations

Prolonged Treatment With Almitrine for Refractory Hypoxemia in Adult Respiratory Distress Syndrome

1994 • 12 citations

The pharmacological properties of almitrine bismesylate.

1986 • 3 citations