ASK1 (MAP3K5) as a potential therapeutic target in malignant fibrous histiocytomas with 12q14–q15 and 6q23 amplifications

Induction of Apoptosis by ASK1, a Mammalian MAPKKK That Activates SAPK/JNK and p38 Signaling Pathways

1997 • 2,284 citations

PPARγ Is Required for the Differentiation of Adipose Tissue In Vivo and In Vitro

1999 • 1,963 citations

PPARγ Is Required for Placental, Cardiac, and Adipose Tissue Development

1999 • 1,904 citations

Signal transduction by the c-Jun N-terminal kinase (JNK) — from inflammation to development

1998 • 1,551 citations

Inhibition of Adipogenesis Through MAP Kinase-Mediated Phosphorylation of PPARγ

1996 • 1,033 citations

Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor γ and the retinoid X receptor

1997 • 655 citations

Quantitative mapping of amplicon structure by array CGH identifies CYP24 as a candidate oncogene

2000 • 598 citations

Transcriptional Activation by Peroxisome Proliferator-activated Receptor γ Is Inhibited by Phosphorylation at a Consensus Mitogen-activated Protein Kinase Site

1997 • 544 citations

Activation of Apoptosis Signal-Regulating Kinase 1 (ASK1) by Tumor Necrosis Factor Receptor-Associated Factor 2 Requires Prior Dissociation of the ASK1 Inhibitor Thioredoxin

2000 • 533 citations

Induction of solid tumor differentiation by the peroxisome proliferator-activated receptor-γ ligand troglitazone in patients with liposarcoma

1999 • 501 citations

Reactive Oxygen Species- and Dimerization-induced Activation of Apoptosis Signal-regulating Kinase 1 in Tumor Necrosis Factor-α Signal Transduction

1998 • 351 citations

Interdomain communication regulating ligand binding by PPAR-γ

1998 • 344 citations

Structure of the supernumerary ring and giant rod chromosomes in adipose tissue tumors

1999 • 268 citations

Phenotypic Change from Transformed to Normal Induced by Benzoquinonoid Ansamycins Accompanies Inactivation of p60^src in Rat Kidney Cells Infected with Rous Sarcoma Virus

1986 • 222 citations

A20 Inhibits Tumor Necrosis Factor (TNF) Alpha-Induced Apoptosis by Disrupting Recruitment of TRADD and RIP to the TNF Receptor 1 Complex in Jurkat T Cells

2002 • 198 citations

Quantification of MYCN, DDX1, and NAG Gene Copy Number in Neuroblastoma Using a Real-Time Quantitative PCR Assay

2002 • 182 citations

Microarray-based copy number and expression profiling in dedifferentiated and pleomorphic liposarcoma.

2002 • 156 citations

Molecular Cloning and Characterization of a Novel Protein Kinase with a Catalytic Domain Homologous to Mitogen-activated Protein Kinase Kinase Kinase

1996 • 149 citations

Leiomyosarcomas and Most Malignant Fibrous Histiocytomas Share Very Similar Comparative Genomic Hybridization Imbalances: An Analysis of a Series of 27 Leiomyosarcomas

2001 • 110 citations

A subgroup of malignant fibrous histiocytomas is associated with genetic changes similar to those of well-differentiated liposarcomas

2002 • 103 citations

Loss of Chromosome 13 is the Most Frequent Genomic Imbalance in Malignant Fibrous Histiocytomas

1999 • 63 citations

A20 zinc finger protein inhibits TNF-induced apoptosis and stress response early in the signaling cascades and independently of binding to TRAF2 or 14-3-3 proteins

2001 • 50 citations

Complexity of 12q13–22 amplicon in liposarcoma: Microsatellite repeat analysis

1997 • 43 citations

The Complexity of the 7p12 Amplicon in Human Astrocytic Gliomas: Detailed Mapping of 246 Tumors

2000 • 22 citations