Mechanisms of repression and de-repression within interphase chromatin

A procedure for the isolation of deoxyribonucleic acid from micro-organisms

1961 • 11,554 citations

Gene Action in the X-chromosome of the Mouse (Mus musculus L.)

1961 • 3,881 citations

ACETYLATION AND METHYLATION OF HISTONES AND THEIR POSSIBLE ROLE IN THE REGULATION OF RNA SYNTHESIS

1964 • 2,410 citations

General Conclusions: Teleonomic Mechanisms in Cellular Metabolism, Growth, and Differentiation

1961 • 1,043 citations

A Morphological Distinction between Neurones of the Male and Female, and the Behaviour of the Nucleolar Satellite during Accelerated Nucleoprotein Synthesis

1949 • 1,000 citations

THE STRUCTURE OF THE DNA-ACRIDINE COMPLEX

1963 • 717 citations

The bases of the nucleic acids of some bacterial and animal viruses: the occurrence of 5-hydroxymethylcytosine

1953 • 602 citations

The Roles of Synthesis and Degradation in the Control of Rat Liver Tryptophan Pyrrolase

1965 • 592 citations

HISTONE, A SUPPRESSOR OF CHROMOSOMAL RNA SYNTHESIS

1962 • 590 citations

Asynchronous Duplication of Chromosomes in Cultured Cells of Chinese Hamster

1960 • 530 citations

Synthesis of RNA and protein during mitosis in mammalian tissue culture cells

1962 • 505 citations

THE NORMAL HUMAN FEMALE AS A MOSAIC OF X-CHROMOSOME ACTIVITY: STUDIES USING THE GENE FOR G-6-PD-DEFICIENCY AS A MARKER

1962 • 503 citations

ANTIBODY FORMATION IN VITRO

1961 • 445 citations

THE PREPARATION AND CHARACTERIZATION OF RIBONUCLEIC ACIDS FROM YEAST

1955 • 443 citations

The Phenomenon of Position Effect

1950 • 436 citations

ON THE ROLE OF HISTONES IN REGULATING RIBONUCLEIC ACID SYNTHESIS IN THE CELL NUCLEUS

1963 • 410 citations

PROTEIN SYNTHESIS IN ISOLATED CELL NUCLEI

1957 • 403 citations

PREFERENTIAL STAINING OF NUCLEIC ACID-CONTAINING STRUCTURES FOR ELECTRON MICROSCOPY

1961 • 383 citations

DEMONSTRATION OF TWO POPULATIONS OF CELLS IN THE HUMAN FEMALE HETEROZYGOUS FOR GLUCOSE-6-PHOSPHATE DEHYDROGENASE VARIANTS

1963 • 369 citations

Variable and Constant Components of Chromosomes

1949 • 363 citations

Cell Specificity of Histones

1950 • 363 citations

DNA Replication Patterns of Human Chromosomes

1963 • 362 citations

EPIGENETIC CONTROL SYSTEMS

1958 • 351 citations

REPRESSED AND ACTIVE CHROMATIN ISOLATED FROM INTERPHASE LYMPHOCYTES

1963 • 345 citations

Formation of the sex chromatin by a single X-chromosome in liver cells of Rattus norvegicus

1959 • 340 citations

Formation and properties of RNA-DNA complexes

1964 • 316 citations

Nuclear Polyanions as De-Repressors of Synthesis of Ribonucleic Acid

1965 • 300 citations

Studies on Chromatin

1964 • 289 citations

Equilibrium sedimentation in density gradients of DNA preparations from animal tissues

1961 • 289 citations

ON THE MECHANISM OF ACTION OF ALDOSTERONE ON SODIUM TRANSPORT: THE ROLE OF RNA SYNTHESIS

1964 • 279 citations

ENZYMATIC INCORPORATION OF RIBONUCLEOSIDE TRIPHOSPHATES INTO THE INTERPOLYNUCLEOTIDE LINKAGES OF RIBONUCLEIC ACID

1960 • 279 citations

Differential Uptake of Tritiated Thymidine into Hetero- and Euchromatin in Melanoplus and Secale

1959 • 274 citations

NUCLEIC ACID SYNTHESIS IN RELATION TO THE CELL DIVISION CYCLE*

1960 • 271 citations

H ³ URIDINE INCORPORATION IN LAMPBRUSH CHROMOSOMES

1962 • 259 citations

Cytogenetic analysis of major heterochromatic elements (especially Xh and Y) in Drosophila melanogaster, and the theory of “heterochromatin”

1959 • 251 citations

A PARADOXICAL EFFECT OF ACTINOMYCIN D: THE MECHANISM OF REGULATION OF ENZYME SYNTHESIS BY HYDROCORTISONE

1964 • 249 citations

ACTIVE AND INACTIVE REGIONS OF NUCLEAR CHROMATIN AS REVEALED BY ELECTRON MICROSCOPE AUTORADIOGRAPHY

1964 • 248 citations

Mammalian X-Chromosome Action: Inactivation Limited in Spread and in Region of Origin

1963 • 247 citations

Actinomycin: Correlation of Structure and Function of Its Complexes with Purines and DNA

1964 • 228 citations

THE COMPOSITION AND STRUCTURE OF ISOLATED CHROMOSOMES

1951 • 214 citations

Autoantibodies and Disease

1964 • 202 citations

Heterochromatic Chromosomes in the Coccids

1964 • 200 citations

Genetics of Mammalian Sex Chromosomes

1961 • 200 citations

Further fractionations of histones from calf thymus

1962 • 197 citations

Aqueous Dispersions of Phosphatidylserine

1964 • 186 citations

BIOCHEMISTRY OF ACTINOMYCINS.

1963 • 180 citations

INTERACTION OF NUCLEIC ACIDS, I. PHYSICAL BINDING OF THYMINE, ADENINE, STEROIDS, AND AROMATIC HYDROCARBONS TO NUCLEIC ACIDS

1964 • 174 citations

Serial Transplantation of Embryonic Nuclei

1956 • 171 citations

Changes in the nuclei of differentiating endoderm cells as revealed by nuclear transplantation

1957 • 169 citations

Properties of chromosomal nucleohistone

1963 • 169 citations

NUCLEIC ACID AND PROTEIN METABOLISM DURING THE MITOTIC CYCLE IN VICIA FABA

1961 • 165 citations

Cytoplasmic Interaction between Macrophages and Lymphocytic Cells in Antibody Synthesis

1964 • 162 citations

Actinomycin and Puromycin: Effects on Sequential Gene Activation by Ecdysone

1964 • 159 citations

Beitrage zur Kenntniss der Zelle und ihrer Lebenserscheinungen

1879 • 156 citations

ISOLATION OF A NUCLEAR RNA FRACTION RESEMBLING DNA IN ITS BASE COMPOSITION

1962 • 151 citations

STUDIES ON ACIDIC NUCLEAR PROTEINS OF THE WALKER TUMOR AND LIVER.

1963 • 151 citations

THE RELATIONSHIP BETWEEN RNA SYNTHESIS AND LOOP STRUCTURE IN LAMPBRUSH CHROMOSOMES

1963 • 145 citations

IDENTITY OF DNA AND DIVERSITY OF MESSENGER RNA MOLECULES IN NORMAL MOUSE TISSUES

1964 • 142 citations

III. DNA SYNTHESIS IN HUMAN CHROMOSOMES*

1962 • 138 citations

OBSERVATIONS ON THE DEVELOPMENT OF ERYTHROCYTES IN MAMMALIAN FETAL LIVER

1962 • 135 citations

Virus-Specific Double-Stranded RNA in Poliovirus-Infected Cells

1964 • 134 citations

THE BINDING OF ESTRADIOL IN THE UTERUS: A MECHANISM FOR DEREPRESSION OF RNA SYNTHESIS

1964 • 134 citations

THE STATE OF THE CHROMOSOMES IN THE INTERPHASE NUCLEUS

1949 • 126 citations

The occurrence of sex chromatin in early human and macaque embryos.

1957 • 125 citations

Studies of Energy-yielding Reactions in Thymus Nuclei

1963 • 119 citations

The Heterogeneity of the Immune Response

1964 • 119 citations

THE SOMATIC CHOMOSOMES OF MAN

1958 • 115 citations

Binding of basic proteins to DNA

1965 • 113 citations

Composition and metabolism of lipids within repressed and active chromatin of interphase lymphocytes

1965 • 113 citations

Opening Address: The Teleonomic Significance of Biosynthetic Control Mechanisms

1961 • 110 citations

RNA and DNA metabolism in human tissue culture cells studied with tritiated cytidine

1960 • 104 citations

The effect of actinomycin D on nucleolar and nuclear fine structure in the salivary gland cell of Chironomus thummi

1964 • 104 citations

Inhibition of RNA polymerase by RNA

1963 • 103 citations

HYDROGEN EXCHANGE STUDIES OF DNA STRUCTURE

1965 • 101 citations

UPTAKE OF GLYCINE-N15 BY COMPONENTS OF CELL NUCLEI

1952 • 101 citations

Paramutation and Chromosome Organization

1960 • 95 citations

Observations on nuclear RNA during mitosis in human cancer cells in culture (HeLa-S3), studied with tritiated cytidine

1963 • 92 citations

EVIDENCE FOR THE COMPLETE DNA-DEPENDENCE OF RNA SYNTHESIS IN ISOLATED THYMUS NUCLEI

1962 • 88 citations

Actinomycin D as a Probe for Nucleic Acid Secondary Structure

1964 • 87 citations

Beiträge zur Kenntniss der Zelle und Ihrer Lebenserscheinungen

1880 • 86 citations

The Transplantation of Living Cell Nuclei

1964 • 82 citations

METABOLISM AND MORPHOLOGY OF RIBONUCLEOPROTEIN PARTICLES FROM THE CELL NUCLEUS OF LYMPHOCYTES

1960 • 82 citations

A Model of Specific De-repression within Inter phase Chromatin

1965 • 81 citations

SOME OBSERVATIONS ON PROTEIN METABOLISM IN CHROMOSOMES OF NON-DIVIDING CELLS

1955 • 80 citations

In vitro incorporation of amino acids into the proteins of isolated nuclear ribosomes

1961 • 78 citations

The Absence of Histone in the Bacterium Escherichia coli

1959 • 76 citations

CYTOLOGICAL ASPECTS OF INFORMATION TRANSFER IN CELLULAR DIFFERENTIATION

1963 • 75 citations

COMPOSITION OF THE NUCLEUS AND CHROMOSOMES IN THE LAMPBRUSH STAGE OF THE NEWT OÖCYTE

1963 • 66 citations

Immunogenic Sub-Cellular Particles Obtained from Spleens of Antigen-Injected Mice

1962 • 66 citations

Polyoma Virus Genetic Material in a Virus-Free Polyoma-Induce Tumor

1964 • 63 citations

Studies on Energy-yielding Reactions in Thymus Nuclei

1963 • 60 citations

SOME EFFECTS OF SUBSTITUTING THE DEOXYRIBONUCLEIC ACID OF ISOLATED NUCLEI WITH OTHER POLYELECTROLYTES

1958 • 58 citations

Carcinogenesis; a facet of living processes.

1954 • 53 citations

DELAYED FLUORESCENCE IN DNA-ACRIDINE DYE COMPLEXES

1964 • 52 citations

A procedure for the isolation of RNA fractions resembling DNA with respect to nucleotide composition

1963 • 51 citations

Inhibition of Ribonucleic Acid-Polymerase Reactions by Actinomycin and Proflavine

1963 • 49 citations

The Absence of Histone in the Bacterium Escherichia coli

1959 • 47 citations

INTERACTION BETWEEN DENATURED DNA, POLYRIBONUCLEOTIDES, AND RIBOSOMAL RNA: ATTEMPTS AT PREPARATIVE SEPARATION OF THE COMPLEMENTARY DNA STRANDS

1964 • 45 citations

ASYMMETRIC SYNTHESIS OF RNA IN VITRO: DEPENDENCE ON DNA CONTINUITY AND CONFORMATION

1964 • 45 citations

Nuclear Proteins of Neoplastic Cells

1964 • 44 citations

Studies on histones. 5. The histones of the Crocker sarcoma and spontaneous mammary tumours of mice

1963 • 44 citations

THE DIFFERENTIAL CAPACITY FOR RNA SYNTHESIS AMONG CHROMOSOMES: A CYTOLOGICAL APPROACH

1964 • 44 citations

HYDROGEN EXCHANGE STUDIES OF sRNA

1965 • 44 citations

CONTRIBUTIONS TO THE KNOWLEDGE OF THE CELL AND ITS VITAL PROCESSES

1965 • 43 citations

Incorporation of P32 into the “Phosphoprotein” Fraction of Mammalian Tissue

1953 • 41 citations

Mechanisms of Synthesis and Control of Protein and Ribonucleic Acid Synthesis in the Cell Nucleus

1963 • 40 citations

STRAND SELECTIVE TRANSCRIPTION OF T4 DNA IN VITRO

1964 • 37 citations

Ultrastructural Continuity between Active and Repressed Chromatin

1965 • 36 citations

Template and “DNA-like” ribonucleic acids as distinct entities in a preparation from rat liver

1965 • 33 citations

SOLUBLE NUCLEAR PROTEINS OF LIVER AND TUMOR IN AZO DYE CARCINOGENESIS.

1964 • 31 citations

METHYLCHOLANTHRENE-INDUCED CHANGES IN RAT LIVER NUCLEAR RNA

1964 • 31 citations

Staining of Bacteriophage Nucleic Acids with Acridine Orange

1965 • 27 citations

THE ENZYMATIC SYNTHESIS OF A CIRCULAR DNA-RNA HYBRID

1964 • 27 citations

Distribution of Ribonucleic Acid in Tumour Cells During Mitosis

1957 • 26 citations

Chromatography and electrophoresis of nuclear soluble proteins

1964 • 23 citations

RECOGNITION OF ALTERED PATTERNS OF MESSENGER RNA SYNTHESIS IN A MOUSE HEPATOMA.

1964 • 23 citations

Chromosome Number and Morphology of a Human Preinvasive Neoplasm

1964 • 22 citations

Evidences for inductive properties of the micromere-RNA in sea-urchin embryos

1965 • 20 citations

CHICK CEPHALOGENESIS, I. THE EFFECT OF RNA ON EARLY CEPHALIC DEVELOPMENT

1963 • 20 citations

Acridine orange and acriflavin inhibit deoxyribonuclease action

1963 • 19 citations

Phosphorylserine sequences in phosphoproteins from Ehrlich ascites cells

1964 • 16 citations

A Hypothesis for Deoxyribonucleic Acid Transcription and Messenger Ribonucleic Acid Synthesis in vivo

1964 • 16 citations

A report of sex chromatin in human tumor tissue culture

1958 • 15 citations

Chromosome Aberrations: Their Role in the Etiology of Murine Leukemia

1964 • 14 citations

Base Ratios in DNA in Male and Female Pseudococcus citri

1964 • 14 citations

Nuclear Materials and Nuclear Change in Differentiation

1961 • 12 citations

THE ETIOLOGY OF LEUKEMIAS, LYMPHOMAS, AND CANCERS. A UNIFYING CONCEPT AND ITS RELATION TO THE AGING PROCESS.

1964 • 12 citations

INTRODUCTION OF SPECIFIC DRUG RESISTANCE PROPERTIES BY PURIFIED RNA-CONTAINING FRACTIONS FROM PNEUMOCOCCUS

1964 • 11 citations

Interaction between deoxypentosenucleic acid and histone in strong saline

1957 • 8 citations

RNA turnover rates in normal peripheral mononuclear leucocytes

1964 • 7 citations

THE ETIOLOGY OF LEUKEMIAS, LYMPHOMAS, AND CANCERS

1964 • 7 citations