Diuretics and potassium metabolism: A reassessment of the need, effectiveness and safety of potassium therapy

Digitalis Intoxication

1971 • 579 citations

The chemical composition of the human body.

1951 • 369 citations

Diuretic-Induced Hyponatremia

1971 • 329 citations

Micropuncture study of distal tubular potassium and sodium transport in rat nephron

1966 • 305 citations

TOTAL SODIUM, POTASSIUM AND CHLORIDE IN ADULT MAN 1

1956 • 290 citations

Clinical and Metabolic Characteristics of Hyperosmolar Nonketotic Coma

1971 • 210 citations

THE MEASUREMENT OF EXCHANGEABLE POTASSIUM IN MAN BY ISOTOPE DILUTION 1

1950 • 198 citations

Total-body potassium in health: effects of age, sex, height, and fat

1974 • 179 citations

Adverse reactions to spironolactone. A report from the Boston Collaborative Drug Surveillance Program

1973 • 161 citations

DETERIORATION OF GLUCOSE TOLERANCE IN HYPERTENSIVE PATIENTS ON PROLONGED DIURETIC TREATMENT

1976 • 152 citations

MALIGNANT HYPERPYREXIA

1975 • 152 citations

Acute Hyperkalemia Induced by Hyperglycemia: Hormonal Mechanisms

1976 • 138 citations

Role of Anions in Metabolic Alkalosis and Potassium Deficiency

1968 • 132 citations

Adverse Reactions to Spironolactone

1973 • 125 citations

Body sodium and potassium. III. Interrelated trends in alimentary, renal and cardiovascular disease; lack of correlation between body stores and plasma concentration.

1954 • 125 citations

A Study by Continuous Microperfusion of Water and Electrolyte Movements in the Loop of Henle and Distal Tubule of the Rat

1969 • 124 citations

Water and electrolyte content of cardiac and skeletal muscle in heart failure and myocardial infarction

1952 • 118 citations

TOTAL-BODY POTASSIUM IN HYPERTENSIVE PATIENTS DURING PROLONGED DIURETIC THERAPY

1972 • 118 citations

Potassium transport across renal distal tubules during acid-base disturbances

1971 • 112 citations

Adverse Reactions to Potassium Chloride

1974 • 110 citations

TOTAL EXCHANGEABLE SODIUM, TOTAL EXCHANGEABLE POTASSIUM, AND TOTAL BODY WATER IN EDEMATOUS PATIENTS WITH CIRRHOSIS OF THE LIVER AND CONGESTIVE HEART FAILURE1

1958 • 106 citations

Clinical Disorders of Fluid and Electrolyte Metabolism

1973 • 102 citations

Effect of Thiazide Diuretics on Plasma Volume, Body Electrolytes, and Excretion of Aldosterone in Hypertension

1961 • 100 citations

TOTAL BODY AND SERUM POTASSIUM DURING PROLONGED THIAZIDE THERAPY FOR ESSENTIAL HYPERTENSION

1975 • 98 citations

WATER EXCRETION IN POTASSIUM-DEFICIENT MAN*

1961 • 97 citations

A Comparison of the Effects of Hydrochlorothiazide and of Frusemide in the Treatment of Hypertensive Patients

1971 • 93 citations

The Antihypertensive Actions of Benzothiadiazines

1961 • 83 citations

Body Composition Changes in Hypertensive Subjects on Long-term Oral Diuretic Therapy

1970 • 80 citations

THE ROLE OF DIURETICS IN THE MANAGEMENT OF HYPERTENSION

1960 • 75 citations

Assessment of body potassium stores

1977 • 74 citations

The effect of uncomplicated potassium depletion on urine acidification

1970 • 74 citations

Sites and mechanisms of potassium transport along the renal tubule

1977 • 74 citations

Glucose Intolerance with Hypokalemia: Failure of Short-term Potassium Depletion in Normal Subjects to Reproduce the Glucose and Insulin Abnormalities of Clinical Hypokalemia

1973 • 73 citations

Potassium-Induced Lesions of the Small Bowel

1965 • 71 citations

Modern Diuretic Therapy in the Treatment of Cardiovascular and Renal Disease.

1973 • 71 citations

Diuretic and Diet Treatment of Hypertension

1974 • 70 citations

POTASSIUM AND OPEN-HEART SURGERY

1966 • 61 citations

The Distribution of Body Fluids in Congestive Heart Failure

1951 • 61 citations

Body and Serum Potassium in Liver Disease

1965 • 61 citations

Total Body Potassium in Long-Term Frusemide Therapy: Is Potassium Supplementation Necessary?

1974 • 59 citations

Adverse Reactions to Spironolactone

1973 • 59 citations

Death after Combined Dexamphetamine and Phenelzine

1965 • 57 citations

EFFECTS OF BENZOTHIADIAZINES ON SERUM AND TOTAL BODY ELECTROLYTES*

1960 • 57 citations

EXCHANGEABLE POTASSIUM IN WASTING, AMYOTROPHY, HEART-DISEASE, AND CIRRHOSIS OF THE LIVER

1961 • 55 citations

The Effect of Thiazides, Chlorthalidone and Furosemide on Muscle Electrolytes and Muscle Glycogen in Normal Subjects

1966 • 54 citations

Role of glucoregulatory hormones in potassium homeostasis

1977 • 52 citations

Total and ‘Exchangeable’ Potassium in Humans

1955 • 48 citations

The critical role of the adrenal gland in the renal regulation of acid-base equilibrium during chronic hypotonic expansion. Evidence that chronic hyponatremia is a potent stimulus to aldosterone secretion.

1976 • 47 citations

Potassium-Induced Lesions of the Small Bowel

1965 • 46 citations

THE EXCHANGEABLE POTASSIUM CONTENT OF NORMAL WOMEN 12

1952 • 42 citations

SERUM-POTASSIUM LEVELS AS AN INDEX OF BODY CONTENT

1957 • 42 citations

Potassium-sparing Agents during Diuretic Therapy in Hypertension

1971 • 41 citations

LEUCOCYTE ELECTROLYTES IN CARDIAC AND NON-CARDIAC PATIENTS RECEIVING DIURETICS

1974 • 41 citations

Slow release potassium chloride treatment.

1975 • 39 citations

Management of Potassium Problems During Long-Term Diuretic Therapy

1974 • 37 citations

Possible predisposition of diabetic patients to hyperkalemia following administration of potassium-retaining diuretic, amiloride (MK 870)

1970 • 36 citations

Clinical disturbances in serum sodium and potassium in relation to alteration in total exchangeable sodium, exchangeable potassium and total body water

1963 • 36 citations

THE EFFECT OF MEFRUSIDE ON PLASMA AND MUSCLE ELECTROLYTES AND BLOOD PRESSURE IN NORMAL SUBJECTS AND IN PATIENTS WITH ESSENTIAL HYPERTENSION

1973 • 35 citations

Effects of Chlorthalidone on Serum and Total Body Potassium in Hypertensive Patients

1976 • 34 citations

PROBLEMS INVOLVED IN ACCURATELY MEASURING THE K CONTENT OF THE HUMAN BODY*

1963 • 34 citations

Potassium Depletion in Severe Heart Disease

1969 • 33 citations

Hyperkalemia after triamterene in diabetic patients

1972 • 32 citations

AMILORIDE ('MK 870') IN PATIENTS WITH ASCITES DUE TO CIRRHOSIS OF THE LIVER

1968 • 32 citations

Leucocyte Potassium in Uraemia: Comparisons with Erythrocyte Potassium and Total Exchangeable Potassium

1972 • 32 citations

Dosage of potassium chloride elixir to correct thiazide-induced hypokalemia.

1974 • 32 citations

Hyperglycemia and Inhibition of Insulin Secretion during Administration of Diazoxide and Trichlormethiazide in Man

1969 • 29 citations

Bioavailability of potassium from a slow‐release tablet

1973 • 28 citations

Exchangeable body potassium and sodium in patients in congestive heart failure

1966 • 26 citations

Exchangeable Potassium Content of the Body in Congestive Failure

1956 • 26 citations

Dilemmas in Potassium Therapy

1973 • 25 citations

Potassium and Sodium Distribution in Cardiac Failure

1971 • 25 citations

Potassium Supplements in Patients Receiving Long-Term Diuretics for Oedema

1976 • 24 citations

Dosage of Potassium Chloride Elixir to Correct Thiazide-lnduced Hypokalemia

1974 • 23 citations

Cardiac arrest due to oral potassium administration

1975 • 23 citations

Effect of Potassium Supplements on the Exchangeable Potassium in Chronic Heart Disease

1970 • 22 citations

DIURETICS, POTASSIUM DEPLETION, AND CARBOHYDRATE INTOLERANCE

1971 • 22 citations

Alterations in the Body Potassium Content in Cirrhosis of the Liver

1953 • 21 citations

Exchangeable potassium in heart disease: Long-term effects of potassium supplements and amiloride

1972 • 21 citations

THE EXCHANGEABLE POTASSIUM CONTENT IN DISEASE STATES 12

1952 • 20 citations

A Comparison of Leucocyte Potassium Content with other Measurements in Potassium-Depleted Rabbits

1972 • 19 citations

Significance of hypokalaemia due to diuretics.

1973 • 18 citations

Water, sodium, potassium, and chloride content of skeletal muscle in fit and ill subjects

1968 • 15 citations

Studies of potassium depletion using direct measurements of total-body potassium.

1970 • 12 citations

Reproducibility of body composition measurements in a single individual.

1969 • 12 citations

The carbohydrate metabolism of normal subjects during potassium depletion

1971 • 12 citations

Abnormalities of cellular potassium concentration in uncompensated and compensated congestive heart failure.

1973 • 12 citations

Suicide by Oral Ingestion of a Potassium Preparation

1969 • 11 citations

Potassium supplements.

1969 • 10 citations

Down with Plasma! Intracellular Chemical Pathology Studied by Analysis of Cells of Solid Tissues, Erythrocytes, and Leukocytes

1969 • 8 citations

Potassium supplementation during diuretic therapy.

1975 • 5 citations

Diuretics and Adverse Gastrointestinal Reaction

1971 • 4 citations

POTASSIUM STRICTURES OF THE UPPER ALIMENTARY TRACT

1976 • 4 citations

Potassium deficiency in hypertensives treated with diuretics. Analysis of three alternative treatments by an oral test for potassium deficiency

1974 • 2 citations

Effects of Hydrochlorothiazide and Amiloride on Potassium Distribution in Skeletal Muscle of the Rat

1973 • 1 citations