Non-invasive intranasal insulin-like growth factor-I reduces infarct volume and improves neurologic function in rats following middle cerebral artery occlusion

Reversible middle cerebral artery occlusion without craniectomy in rats.

1989 • 6,875 citations

Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination.

1986 • 2,584 citations

A Semiautomated Method for Measuring Brain Infarct Volume

1990 • 1,610 citations

A role for IGF-1 in the rescue of CNS neurons following hypoxic-ischemic injury

1992 • 381 citations

Tactile extinction: Distinguishing between sensorimotor and motor asymmetries in rats with unilateral nigrostriatal damage

1982 • 323 citations

IGF-I and IGF-II protect cultured hippocampal and septal neurons against calcium-mediated hypoglycemic damage

1992 • 253 citations

Intranasal administration of insulin-like growth factor-I bypasses the blood–brain barrier and protects against focal cerebral ischemic damage

2001 • 244 citations

Seizures and recovery from experimental brain damage

1988 • 213 citations

The Effects of IGF-1 Treatment after Hypoxic-Ischemic Brain Injury in Adult Rats

1993 • 202 citations

Aminoguanidine Ameliorates and <scp>l</scp> -Arginine Worsens Brain Damage From Intraluminal Middle Cerebral Artery Occlusion

1996 • 184 citations

Growth factors protect neurons against excitotoxic/ischemic damage by stabilizing calcium homeostasis.

1993 • 104 citations

Displacement of insulin-like growth factors from their binding proteins as a potential treatment for stroke

1998 • 92 citations

Spatial Cognitive Performance after Chronic Focal Cerebral Ischemia in Rats

1999 • 78 citations

Middle cerebral artery occlusion in the rat: consistent protocol for a model of stroke

1998 • 70 citations

Sensorimotor cortical lesion effects and treatment with nimodipine

1990 • 15 citations