Recombinant interleukin 2 allows the differentiation of Thy 1.2+ LAK cells from nude mouse spleen cells

Selective in Vitro Growth of T Lymphocytes from Normal Human Bone Marrows

1976 • 2,458 citations

Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes.

1982 • 2,228 citations

Natural cytotoxic reactivity of mouse lymphoid cells against syngeneic and allogeneic tumors. I. Distribution of reactivity and specificity

1975 • 1,308 citations

Cell-Mediated Cytotoxicity, Allograft Rejection, and Tumor Immunity

1974 • 1,161 citations

Regression of established pulmonary metastases and subcutaneous tumor mediated by the systemic administration of high-dose recombinant interleukin 2.

1985 • 737 citations

Adoptive Immunotherapy of Established Pulmonary Metastases with LAK Cells and Recombinant Interleukin-2

1984 • 687 citations

Lymphokine-activated killer cell phenomenon. II. Precursor phenotype is serologically distinct from peripheral T lymphocytes, memory cytotoxic thymus-derived lymphocytes, and natural killer cells

1983 • 477 citations

Lymphokine-activated killer cell phenomenon. III. Evidence that IL-2 is sufficient for direct activation of peripheral blood lymphocytes into lymphokine-activated killer cells.

1983 • 355 citations

The in vitro generation and sustained culture of nude mouse cytolytic T-lymphocytes.

1979 • 268 citations

T-cell-derived helper factor allows in vivo induction of cytotoxic T cells in nu/nu mice

1980 • 228 citations

Natural killer (NK) cells as a responder to interleukin 2 (IL 2). I. Proliferative response and establishment of cloned cells.

1983 • 196 citations

Observations on the immunobiology of 'nude' mice.

1971 • 156 citations

Host Responses Within Solid Tumors. I. Monocytic Effector Cells Within Rat Sarcomas<xref ref-type="fn" rid="fn2">2</xref>

1975 • 96 citations

Suppression of alloimmune cytotoxic T lymphocyte (CTL) generation by depletion of NK cells and restoration by interferon and/or interleukin 2.

1985 • 65 citations

Use of millipore diffusion chambers to assay in vivo IL-2 activity

1985 • 14 citations

Different response of mouse thymocyte subpopulations to interleukin 2 and concanavalin A.

1984 • 11 citations

Mitogenic effect of IL 2 on non-thymic and thymic lymphocytes of the mouse.

1984 • 9 citations