Adrenoreceptor interactions of the enantiomers and metabolites of mianserin: are they responsible for the antidepressant effect?

Differential effects of antidepressant treatment on brain monoaminergic receptors

1980 • 222 citations

Chronic antidepressant therapy and associated changes in central monoaminergic receptor functioning

1983 • 160 citations

American Pharmaceutical Association

1914 • 148 citations

Functional evidence for two stereochemically different alpha-2 adrenoceptors regulating central norepinephrine and serotonin release.

1983 • 123 citations

CRC handbook of stereoisomers : drugs in psychopharmacology

1984 • 69 citations

A study of the sensitivity of rat brain alpha2-adrenoceptors during chronic antidepressant treatments

1982 • 65 citations

Supersensitivity of central noradrenergic presynaptic autoreceptors following chronic treatment with the antidepressant mianserin

1981 • 61 citations

Comparative pharmacology of mianserin, its main metabolites and 6-azamianserin

1982 • 57 citations

The inability of chronic mianserin to block central α2-adrenoceptors

1980 • 57 citations

The potential therapeutic role of the enantiomers and metabolites of mianserin.

1983 • 56 citations

Mianserin: Cardiovascular effects in elderly patients

1983 • 42 citations

The Effect of Mianserin on Alpha-2 Adrenergic Receptor Function in Depressed Patients

1984 • 40 citations

Differences in presynaptic ?-blockade, noradrenaline uptake inhibition, and potential antidepressant activity between (+)- and (-)mianserin

1981 • 38 citations

The effect of (±)mianserin and its enantiomers on the behavioural hyperactivity of the olfactory-bulbectomized rat

1984 • 35 citations

Determination of Mianserin and Metabolites in Plasma by Liquid Chromatography with Electrochemical Detection

1982 • 30 citations

Chronic drug treatments induce changes in the sensitivity of presynaptic autoreceptors but not of presynaptic heteroreceptors

1983 • 25 citations

Mianserin

2015 • 25 citations

Differential blockade by (?)mianserin of the alpha2-adrenoceptors mediating inhibition of noradrenaline and serotonin release from rat brain synaptosomes

1983 • 19 citations

Pharmacodynamic studies on mianserin and its interaction with clonidine

1981 • 16 citations

Serotoninergic Mechanisms of Antidepressant Drugs

1981 • 15 citations

Absence of an effect of mianserin on the actions of clonidine or methyldopa in hypertensive patients

1983 • 14 citations

Interaction between mianserin and clonidine at ? 2-Adrenoceptors

1982 • 11 citations

Antidepressants and ∝-adrenoceptors

1983 • 6 citations

Mianserin pharmacokinetics—a reply

1983 • 1 citations

Differential mode of antagonism of 5-hydroxytryptamine-induced pressor effects by (+)- and (-)-mianserin in pithed rats

1983 • 1 citations