Evaluation in rats of the somnogenic, pyrogenic, and central nervous system depressant effects of muramyl dipeptide

Interleukin-1

1984 • 1,625 citations

Insomnia and Its Treatment

1985 • 1,069 citations

Minimal structural requirements for adjuvant activity of bacterial peptidoglycan derivatives

1974 • 1,038 citations

Prevalence of sleep disorders in the Los Angeles metropolitan area

1979 • 899 citations

Production of prostaglandin E and an interleukin-1 like factor by cultured astrocytes and C6 glioma cells.

1982 • 754 citations

Sleep-promoting effects of endogenous pyrogen (interleukin-1)

1984 • 450 citations

Prevalence of sleep disturbance in a primarily urban Florida county

1976 • 348 citations

Insomnia and its treatment

1984 • 301 citations

Sleep-promoting effects of muramyl peptides.

1982 • 216 citations

Chronic use of benzodiazepines and psychomotor and cognitive test performance

1986 • 186 citations

The composition of sleep-promoting factor isolated from human urine.

1982 • 182 citations

Sleep Disorders: Basic and Clinical Research

1983 • 164 citations

Peptidoglycans as promoters of slow-wave sleep. II. Somnogenic and pyrogenic activities of some naturally occurring muramyl peptides; correlations with mass spectrometric structure determination.

1984 • 105 citations

Differential sleep-promoting effects of five sleep substances nocturnally infused in unrestrained rats.

1984 • 100 citations

Central pyrogenic activity of muramyl dipeptide.

1980 • 94 citations

Correlation between the immunoadjuvant activities and pyrogenicities of synthetic N-acetylmuramyl-peptides or -amino acids.

1976 • 83 citations

Salicylate: Action on Normal Body Temperature in Rats

1972 • 72 citations

Effect of antipyretic drugs on circadian rhythm in body temperature of rats

1987 • 67 citations

Muramyl dipeptide-induced sleep and fever: effects of ambient temperature and time of injections

1988 • 49 citations

Benzodiazepine dependence

1984 • 36 citations

Interaction of diazepam or lorazepam with alcohol

1985 • 33 citations

Triazolam and ethanol interaction: Kinetic and dynamic consequences

1985 • 33 citations

Control of the circadian rhythm of the body temperature in the rat

1974 • 31 citations

Antagonism of the acute electroencephalographic and behavioral effects of morphine in the rat by depletion of brain biogenic amines

1973 • 16 citations

Effects of a muramyl dipeptide on the temperature and sleep-wake cycles of the squirrel monkey

1984 • 15 citations

Muramyl dipeptide does not induce slow-wave sleep or fever in rats

1984 • 15 citations

Dissociation between muramyl dipeptide-induced fever and changes in plasma metal levels

1986 • 14 citations

Assessment of hypnotic effects in the rat: Influence of the sleep‐awake cycle

1988 • 14 citations

Specific absorption with monoclonal antibodies to muramyl dipeptide of the pyrogenic and somnogenic activities of rabbit monokine.

1984 • 13 citations

Muramyl Peptides, Serotonergic System, and Sleep

1987 • 10 citations

Effects of salicylate and indomethacin in nonfebrile rats at different ambient temperatures

1985 • 8 citations