Differential ability of cells to promote oxidation of low density lipoproteins in vitro

The pathogenesis of atherosclerosis: a perspective for the 1990s

1993 • 10,730 citations

A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples

1978 • 6,494 citations

Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man.

1989 • 1,914 citations

Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids.

1984 • 1,631 citations

Low density lipoprotein undergoes oxidative modification in vivo.

1989 • 1,537 citations

Autoantibody against oxidised LDL and progression of carotid atherosclerosis

1992 • 1,332 citations

Oxidatively modified low density lipoproteins: a potential role in recruitment and retention of monocyte/macrophages during atherogenesis.

1987 • 1,152 citations

Minimally modified low density lipoprotein induces monocyte chemotactic protein 1 in human endothelial cells and smooth muscle cells.

1990 • 1,147 citations

Antiatherogenic effect of probucol unrelated to its hypocholesterolemic effect: evidence that antioxidants in vivo can selectively inhibit low density lipoprotein degradation in macrophage-rich fatty streaks and slow the progression of atherosclerosis in the Watanabe heritable hyperlipidemic rabbit.

1987 • 1,051 citations

Enhanced macrophage degradation of low density lipoprotein previously incubated with cultured endothelial cells: recognition by receptors for acetylated low density lipoproteins.

1981 • 1,037 citations

Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia.

1987 • 885 citations

Lysophosphatidylcholine: a chemotactic factor for human monocytes and its potential role in atherogenesis.

1988 • 655 citations

Lipoprotein oxidation and lipoprotein-induced cytotoxicity.

1983 • 545 citations

Superoxide-mediated modification of low density lipoprotein by arterial smooth muscle cells.

1986 • 516 citations

Stimulation of lipid peroxidation and hydroxyl-radical generation by the contents of human atherosclerotic lesions

1992 • 463 citations

A role for endothelial cell lipoxygenase in the oxidative modification of low density lipoprotein.

1989 • 417 citations

Macrophage oxidation of low density lipoprotein generates a modified form recognized by the scavenger receptor.

1986 • 417 citations

The Role of Oxidized Low-Density Lipoproteins in the Pathogenesis of Atherosclerosis

1992 • 386 citations

Superoxide anion participation in human monocyte-mediated oxidation of low-density lipoprotein and conversion of low-density lipoprotein to a cytotoxin.

1989 • 231 citations

Role of superoxide in endothelial-cell modification of low-density lipoproteins

1988 • 228 citations

Analogous pathobiologic mechanisms in glomerulosclerosis and atherosclerosis.

1991 • 183 citations

Role of endothelial cells and their products in the modification of low-density lipoproteins

1986 • 159 citations

Activated human monocytes oxidize low-density lipoprotein by a lipoxygenase-dependent pathway.

1990 • 132 citations

Cellular Mechanisms of Lipid Injury in the Glomerulus

1993 • 104 citations

Culture of human endothelial cells.

1980 • 102 citations

Oxidation of low density lipoprotein by mesangial cells may promote glomerular injury

1994 • 98 citations

Oxidized low-density lipoprotein in experimental focal glomerulosclerosis

1993 • 83 citations

The oxidative modification of low density lipoprotein by human lymphocytes

1992 • 74 citations

Oxidative modification of low-density lipoproteins by mesangial cells.

1993 • 72 citations

In vivo inhibition of foam cell development by probucol in Watanabe rabbits

1988 • 71 citations

Stable cell lines of T-SV40 immortalized human glomerular mesangial cells

1996 • 65 citations

Renal vasoconstriction caused by short-term cholesterol feeding is corrected by thromboxane antagonist or probucol.

1990 • 61 citations

Oxidized Low-Density Lipoprotein Stimulates Protein Kinase C (PKC) and Induces Expression of PKC-Isotypes via Prostaglandin-H-Synthase in P388D₁Macrophage-Like Cells

1996 • 40 citations

Tubular lipidosis: Epiphenomenon or pathogenetic lesion in human renal disease?

1994 • 36 citations

Activation of 15-lipoxygenase by low density lipoprotein in vascular endothelial cells. Relationship to the oxidative modification of low density lipoprotein

1992 • 30 citations

Extracts of human atherosclerotic lesions can modify low density lipoproteins leading to enhanced uptake by macrophages

1988 • 29 citations

Effects of dietary fatty acids in an animal model of focal glomerulosclerosis

1991 • 28 citations

Human (THP-1) Macrophages Oxidize LDL by a Thiol-Dependent Mechanism

1994 • 27 citations

Oxidation of low-density lipoproteins by rat mesangial cells and the interaction of oxidized low-density lipoproteins with rat mesangial cells in vitro

1993 • 26 citations

Effects of oxidized low density lipoproteins on arachidonic acid metabolism in smooth muscle cells.

1990 • 22 citations

Culture of Human Endothelial Cells

2003 • 3 citations