Neurotoxicity of Endogenous Cysteinylcatechols

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Oxidative Stress, Glutamate, and Neurodegenerative Disorders

1993 • 3,746 citations

Ethanol Inhibits NMDA-Activated Ion Current in Hippocampal Neurons

1989 • 1,456 citations

Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones.

1978 • 1,073 citations

Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?

1992 • 964 citations

Autoxidation versus covalent binding of quinones as the mechanism of toxicity of dopamine, 6-hydroxydopamine, and related compounds toward C1300 neuroblastoma cells in vitro.

1978 • 936 citations

Role of oxidation in the neurotoxic effects of intrastriatal dopamine injections.

1996 • 544 citations

Neurodegenerative Diseases

1994 • 492 citations

Bioenergetic and oxidative stress in neurodegenerative diseases

1995 • 365 citations

Dopamine Neurotoxicity: Inhibition of Mitochondrial Respiration

1995 • 288 citations

Inhibition of mitochondrial NADH dehydrogenase by pyridine derivatives and its possible relation to experimental and idiopathic parkinsonism

1986 • 250 citations

N-Methyl-d-Aspartate Antagonists in the Treatment of Parkinson's Disease

1991 • 221 citations

Possible role of neuromelanin in the pathogenesis of Parkinson's disease

1983 • 210 citations

The apparent autoxidation rate of catechols in dopamine-rich regions of human brains increases with the degree of depigmentation of substantia nigra

1989 • 162 citations

Detection of 5-S-cysteinyldopamine in human brain

1985 • 152 citations

Occurrence and distribution of 5-S-cysteinyl derivatives of dopamine, dopa and dopac in the brains of eight mammalian species

1986 • 152 citations

In Vivo Autoxidation of Dopamine in Guinea Pig Striatum Increases with Age

1990 • 143 citations

Chronic levodopa administration alters cerebral mitochondrial respiratory chain activity

1993 • 140 citations

E-4-hydroxy-2-nonenal is cytotoxic and cross-links cytoskeletal proteins in P19 neuroglial cultures.

1996 • 132 citations

Covalent binding of catechols to proteins through the sulphydryl group

1988 • 113 citations

The inhibition site of MPP+, the neurotoxic bioactivation product of 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine is near the Q-binding site of NADH dehydrogenase

1987 • 107 citations

Mitochondrial function in Parkinson's disease

1992 • 103 citations

Crosslinking of Apolipoprotein E by Products of Lipid Peroxidation

1996 • 93 citations

Methods in biochemical analysis

1991 • 91 citations

Further Insights into the Influence of <scp>l</scp>-Cysteine on the Oxidation Chemistry of Dopamine: Reaction Pathways of Potential Relevance to Parkinson's Disease

1996 • 76 citations

Synthesis and antitumor activity of cysteinyl-3,4-dihydroxyphenylalonines and related compounds

1981 • 66 citations

Synthesis, Redox Properties,in VivoFormation, and Neurobehavioral Effects ofN-Acetylcysteinyl Conjugates of Dopamine: Possible Metabolites of Relevance to Parkinson's Disease

1996 • 65 citations

Structural dependence of the inhibition of mitochondrial respiration and of NADH oxidase by 1-methyl-4-phenylpyridinium (MPP+) analogs and their energized accumulation by mitochondria.

1989 • 55 citations

Selectivity of melaninized nigra-striatal dopamine neurons to degeneration in Parkinson’s disease may depend on iron-melanin interaction

1990 • 47 citations

Synaptosomal Transport of Radiolabel from N‐Acetyl‐Aspartyl‐[³H]Glutamate Suggests a Mechanism of Inactivation of an Excitatory Neuropeptide

1986 • 43 citations

Methods of Biochemical Analysis

1975 • 25 citations

Effects of inhibition of monoamine oxidase on the levels of 5-S-cysteinyl adducts of catechols in dopaminergic regions of the brain of the guinea pig

1991 • 18 citations

Fibroblasts That Express Aromatic Amino Acid Decarboxylase Have Increased Sensitivity to the Synergistic Cytotoxicity of L-Dopa and Manganese

1994 • 15 citations

Neuromelanin-containing neurons are selectively vulnerable in parkinsonism

1988 • 8 citations