What Does Epidermal Growth Factor Do and How Does It Do It?

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Epidermal Growth Factor

1979 • 2,964 citations

G proteins and dual control of adenylate cyclase

1984 • 1,811 citations

Growth factors: Mechanism of action and relation to oncogenes

1984 • 885 citations

C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity.

1984 • 715 citations

Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane

1984 • 656 citations

Enhancement of calcium uptake and phosphatidylinositol turnover by epidermal growth factor in A-431 cells

1981 • 426 citations

Transforming growth factors produced by retrovirus-transformed rodent fibroblasts and human melanoma cells: amino acid sequence homology with epidermal growth factor.

1983 • 403 citations

Epidermal growth factor and potent phorbol tumor promoters induce epidermal growth factor receptor phosphorylation in a similar but distinctively different manner in human epidermoid carcinoma A431 cells.

1984 • 331 citations

Comparison of Epidermal Growth Factor Binding and Receptor Distribution in Normal Human Epidermis and Epidermal Appendages

1984 • 316 citations

Human chromosomal mapping of genes for insulin-like growth factors I and II and epidermal growth factor

1984 • 267 citations

Tumor promoters block tyrosine-specific phosphorylation of the epidermal growth factor receptor.

1984 • 219 citations

Isolation from murine sarcoma cells of novel transforming growth factors potentiated by EGF

1982 • 206 citations

Growth factors: The epidermal growth factor receptor gene and its product

1984 • 187 citations

Production of phosphoinositide-derived messengers

1984 • 163 citations

Mapping of the human gene for epidermal growth factor receptor (EGFR) on the p13→q22 region of chromosome 7

1983 • 112 citations

Restoration of prostacyclin synthase in vascular smooth muscle cells after aspirin treatment: regulation by epidermal growth factor.

1985 • 98 citations

Gene for T-Cell Growth Factor: Location on Human Chromosome 4q and Feline Chromosome B1

1984 • 97 citations

Characterization of the metabolic turnover of epidermal growth factor receptor protein in A‐431 cells

1984 • 94 citations

42,000-molecular weight EGF receptor has protein kinase activity

1984 • 85 citations

Peptide growth factors

1984 • 82 citations

Epidermal Growth Factor: Mechanisms of Action

1982 • 81 citations

EPIDERMAL GROWTH FACTOR*

1982 • 78 citations

Effect of 12‐O‐tetradecanoylphorbol‐13‐acetate (TPA) on the growth inhibitory and increased phosphatidylinositol (PI) responses induced by epidermal growth factor (EGF) in A431 cells

1983 • 71 citations

Epidermal growth factor and phorbol ester actions on human osteosarcoma cells. Characterization of response and nonresponsive cell lines.

1982 • 60 citations

ATP-stimulated interaction between epidermal growth factor receptor and supercoiled DNA

1984 • 58 citations

Oncogenic intelligence: Oncogenes and inositol lipids

1984 • 39 citations

Coated pits in action

1984 • 38 citations

Epidermal Growth Factor Stimulates Release of Arachidonic Acid in Pig Epidermis

1985 • 28 citations