Synthesis of Urokinase‐Type Plasminogen Activator and of Type‐ 1 Plasminogen Activator Inhibitor in Neuronal Cultures of Human Fetal Brain: Stimulation by Phorbol Ester

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

Plasminogen Activators, Tissue Degradation, and Cancer

1985 • 2,584 citations

Plasminogen activator inhibitors

1987 • 957 citations

Plasminogen activator inhibitors

1987 • 764 citations

Fibroblast growth factor promotes survival of dissociated hippocampal neurons and enhances neurite extension.

1986 • 741 citations

Basic fibroblast growth factor supports the survival of cerebral cortical neurons in primary culture.

1986 • 696 citations

Astroglial and fibroblast growth factors have neurotrophic functions for cultured peripheral and central nervous system neurons.

1987 • 495 citations

Plasminogen Activator Release at the Neuronal Growth Cone

1981 • 388 citations

Purification of a factor from human placenta that stimulates capillary endothelial cell protease production, DNA synthesis, and migration.

1986 • 354 citations

Cell-derived proteases and protease inhibitors as regulators of neurite outgrowth

1988 • 337 citations

Morphological and biochemical maturation of neurones cultured in the absence of glial cells

1979 • 325 citations

K-252a: a specific inhibitor of the action of nerve growth factor on PC 12 cells

1988 • 320 citations

Plasminogen activator and collagenase production by cultured capillary endothelial cells

1982 • 279 citations

Plasminogen activator–plasmin system and neuronal migration

1982 • 256 citations

Plasminogen activator inhibitor from human fibrosarcoma cells binds urokinase-type plasminogen activator, but not its proenzyme.

1986 • 232 citations

Plasminogen activator inhibitor type‐1 : reactive center and amino‐terminal heterogeneity determined by protein and cDNA sequencing

1986 • 207 citations

Plasminogen activator secretion by granule neurons in cultures of developing cerebellum.

1981 • 188 citations

Suppression of nerve growth factor-directed neurite outgrowth in PC12 cells by sphingosine, an inhibitor of protein kinase C.

1988 • 172 citations

Phorbol ester induces the biosynthesis of glycosylated and nonglycosylated plasminogen activator inhibitor 2 in high excess over urokinase-type plasminogen activator in human U-937 lymphoma cells.

1987 • 149 citations

The mitogenic signaling pathway but not the plasminogen activator-inducing pathway of basic fibroblast growth factor is mediated through protein kinase C in fetal bovine aortic endothelial cells.

1989 • 133 citations

Effects of phorbol ester tumor promoters and nerve growth factor on neurite outgrowth in cultured human neuroblastoma cells.

1982 • 118 citations

Plasminogen activator in the rodent brain

1981 • 105 citations

Mouse ovarian granulosa cells produce urokinase-type plasminogen activator, whereas the corresponding rat cells produce tissue-type plasminogen activator.

1987 • 76 citations

Effect of tumor promoters on the response of cultured embryonic chick ganglia to nerve growth factor.

1978 • 70 citations

Effects of the tumor promoter 12-O-tetradecanoylphorbol-13-acetate on neurite outgrowth from chick embryo sensory ganglia.

1984 • 64 citations

Plasminogen activator is a mitogen for astrocytes in developing cerebellum

1985 • 64 citations

Fibrinolytic activity of human brain and cerebrospinal fluid.

1969 • 60 citations

Plasminogen activator in the developing rat cerebellum: Biosynthesis and localization in granular neurons

1983 • 59 citations

Brain basic fibroblast growth factor stimulates the release of plasminogen activators by newborn rat cultured astroglial cells

1988 • 58 citations

Transformation of Primary Hamster Brain Cells with JC Virus and Its DNA

1980 • 55 citations

Tumor promoter receptors regulating neurite formation in cultured human neuroblastoma cells.

1983 • 45 citations

Modulation of plasminogen activator activity in human endometrial adenocarcinoma cells by basic fibroblast growth factor and transforming growth factor beta.

1988 • 38 citations

Modulation in the levels and localization of plasminogen activator in differentiating neuroblastoma cells

1983 • 33 citations

Isolation and interrelationships of the multiple molecular tissue-type and urokinase-type plasminogen activator forms produced by cultured human umbilical vein endothelial cells.

1988 • 31 citations

Identification of a pituitary factor responsible for enhancement of plasminogen activator activity in breast tumor cells.

1986 • 30 citations

Characterization of a Mr 20,000 basic fibroblast growth factor-like protein secreted by normal and transformed fetal bovine aortic endothelial cells

1990 • 23 citations

Relationship between circulating plasminogen activators and tumor development in mice.

1986 • 21 citations

Characterization of astrocyte plasminogen activator

1987 • 17 citations

Secretion of plasminogen activator by cerebral astrocytes and its modulation

1987 • 16 citations

Down‐regulation of proteolytic activity in 12‐O‐tetradecanoyl‐phorbol‐13‐acetate‐induced k562 leukemia cell cultures: Depletion of active urokinase by excess type 1 plasminogen activator inhibitor

1989 • 15 citations

An increase in plasminogen activator mRNA occurs at an early stage in ethylnitrosourea-induced transformation of rat brain cells

1986 • 8 citations