Transport Properties Are Not Altered across Caco-2 Cells with Heightened TEER Despite Underlying Physiological and Ultrastructural Changes

Characterization of the Human Colon Carcinoma Cell Line (Caco-2) as a Model System for Intestinal Epithelial Permeability

1989 • 2,127 citations

Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

1991 • 1,787 citations

Epithelial Transport Of Drugs In Cell Culture. I: A Model For Studying The Passive Diffusion Of Drugs Over Intestinal Absorbtive (Caco-2) Cells

1990 • 820 citations

Caco-2 cell monolayers as a model for drug transport across the intestinal mucosa.

1990 • 565 citations

Selective paracellular permeability in two models of intestinal absorption: cultured monolayers of human intestinal epithelial cells and rat intestinal segments.

1993 • 306 citations

The use of cultured epithelial and endothelial cells for drug transport and metabolism studies.

1990 • 272 citations

Uptake of the cephalosporin, cephalexin, by a dipeptide transport carrier in the human intestinal cell line, Caco-2

1990 • 224 citations

Improved in vitro rheological system for studying the effect of fluid shear stress on cultured cells

1993 • 184 citations

Epithelial Transport of Drugs in Cell Culture. II: Effect of Extracellular Calcium Concentration on the Paracellular Transport of Drugs of Different Lipophilicities across Monolayers of Intestinal Epithelial (Caco-2) Cells

1990 • 183 citations

Transport of a large neutral amino acid (phenylalanine) in a human intestinal epithelial cell line: Caco-2

1990 • 163 citations

Transport of bile acids in a human intestinal epithelial cell line, Caco-2

1990 • 136 citations

Epithelial cells in culture as a model for the intestinal transport of antimicrobial agents

1992 • 86 citations

Active hexose transport across cultured human Caco-2 cells: characterisation and influence of culture conditions

1991 • 63 citations

Vitamin E uptake by human intestinal cells during lipolysis in vitro

1990 • 52 citations

Passive transepithelial absorption of thyrotropin-releasing hormone (TRH) via a paracellular route in cultured intestinal and renal epithelial cell lines.

1993 • 51 citations

Cell culture techniques for the study of drug transport

1990 • 50 citations

Protease inhibitors suppress the formation of tight junctions in gastrointestinal cell lines

1992 • 20 citations

Vitamin B12 transport through polarized monolayers of a colon carcinoma cell line

1987 • 16 citations

A practical approach to the synthesis of ¹⁴C‐labeled amino acid and simple peptide

1994 • 2 citations