Role of Platelets in Tumor Cell Metastases

Selection of Successive Tumour Lines for Metastasis

1973 • 1,360 citations

Metastasis: Quantitative Analysis of Distribution and Fate of Tumor Emboli Labeled With <sup>125</sup>I-5-Iodo-2′ -deoxyuridine<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1970 • 990 citations

Tumor heterogeneity and the biology of cancer invasion and metastasis.

1978 • 833 citations

Antimetastatic effects associated with platelet reduction.

1968 • 695 citations

Platelets as a source of fibroblast growth-promoting activity

1974 • 625 citations

Prostacyclin: A Potent Antimetastatic Agent

1981 • 335 citations

Surface Glycoproteins of Normal and Transformed Cells: A Difference Determined by Sialic Acid and a Growth-Dependent Sialyl Transferase

1972 • 256 citations

Increased sialic acid density in surface glycoprotein of transformed and malignant cells--a general phenomenon?

1973 • 233 citations

Correlation between spontaneous metastatic potential, platelet-aggregating activity of cell surface extracts, and cell surface sialylation in 10 metastatic-variant derivatives of a rat renal sarcoma cell line.

1980 • 192 citations

Effects on platelet function of removal of platelet sialic acid by neuraminidase.

1975 • 191 citations

Trauma and the localization of tumor cells

1967 • 155 citations

Electron microscopic observations on formation of pulmonary metastases

1975 • 137 citations

Glycolipid-bound sialic acid in serum: increased levels in mice and humans bearing mammary carcinomas.

1977 • 132 citations

Characterization of Human Platelet Vascular Permeability-Enhancing Activity

1972 • 128 citations

REMOVAL OF SIALIC ACID FROM THE CELL COAT IN TUMOR CELLS AND VASCULAR ENDOTHELLUM, AND ITS EFFECTS ON METASTASIS

1962 • 128 citations

Metastasis: a review of recent advances.

1957 • 118 citations

Sequence of Events in Experimental Metastases of Walker 256 Tumor: Light, Immunofluorescent, and Electron microscopic Observations<xref ref-type="fn" rid="FN2">2</xref>

1971 • 116 citations

Characterization of the platelet-aggregating activity of tumor cells.

1980 • 113 citations

Prostaglandin D2 controls pulmonary metastasis of malignant melanoma cells

1979 • 105 citations

The Role of Blood Platelets in Experimental Metastases

1973 • 97 citations

Inhibition of the platelet-aggregating activity of two human adenocarcinomas of the colon and an anaplastic murine tumor with a specific thrombin inhibitor, dansylarginine N-(3-ethyl-1,5-pentanediyl)amide.

1981 • 95 citations

Prostaglandin D2 formation by malignant melanoma cells correlates inversely with cellular metastatic potential.

1979 • 92 citations

Thrombogenic activity of mouse and human tumors: effects on platelets, coagulation, and fibrinolysis, and possible significance for metastases

1976 • 77 citations

The adhesion of thromboplastic tumour emboli to vessel walls in vivo.

1972 • 76 citations

Aggregation of platelets and cell membrane vesiculation by rat cells transformed in vitro by Rous sarcoma virus.

1978 • 74 citations

Extraction and characterization of a platelet-aggregating material from SV40-transformed mouse 3T3 fibroblasts.

1979 • 69 citations

HÆMATOLOGICAL EFFECTS OF ASPIRIN

1972 • 63 citations

The interaction of platelets, tumor cells, and vascular subendothelium.

1980 • 57 citations

ASPIRIN AND TUMOUR METASTASIS

1972 • 54 citations

The influence of platelet aggregation inhibitors on metastasis formation in mice (3LL)

1976 • 52 citations

Microangiopathic Haemolytic Anaemia and Experimental Tumour‐Cell Emboli

1974 • 47 citations

Inhibition of platelet aggregation by protease inhibitors. Possible involvement of proteases in platelet aggregation

1978 • 47 citations

Cell surface sialylation of glycoproteins and glycosphingolipids in cultured metastatic variant rna‐virus transformed non‐producer BALB/c 3T3 cell lines

1979 • 46 citations

Platelet derived growth factor(s) for a hormone‐responsive rat mammary tumor cell line

1978 • 39 citations

Platelet aggregating material in mouse tumor cells. Removal and regeneration.

1977 • 32 citations

Plasma requirement for the aggregation of rabbit platelets by an aggregating material derived from SV40-transformed 3T3 fibroblasts.

1980 • 27 citations

Studies on platelet aggregation inhibitors in vivo. VIII. Effect of pentoxifylline on spontaneous tumor metastasis.

1979 • 22 citations

Differential release of sialic acid from normal and malignant cells by Vibrio cholerae neuraminidase or influenza virus neuraminidase.

1973 • 21 citations

Effects of trypsin on the platelet-aggregating activity of mouse tumor cells

1977 • 20 citations

Ultrastructure of the Adhesion of HeLa Cells to Human Vein Wall

1969 • 13 citations

Cancer Cell-Endothelial Reactions: The Microinjury Hypothesis and Localized thrombosis in the Formation of Micrometastases

1979 • 10 citations