Identification of Pancreatic Cancer Stem Cells

Prospective identification of tumorigenic breast cancer cells

2003 • 10,067 citations

Stem cells, cancer, and cancer stem cells

2001 • 9,488 citations

Identification of human brain tumour initiating cells

2004 • 7,166 citations

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

1997 • 6,760 citations

Identification of a cancer stem cell in human brain tumors.

2003 • 4,784 citations

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

1994 • 4,563 citations

Tumour stem cells and drug resistance

2005 • 3,535 citations

Isolation and Characterization of Tumorigenic, Stem-like Neural Precursors from Human Glioblastoma

2004 • 2,521 citations

CD44: From adhesion molecules to signalling regulators

2003 • 2,236 citations

Cancerous stem cells can arise from pediatric brain tumors

2003 • 1,800 citations

Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

2003 • 1,465 citations

Wnt signalling regulates adult hippocampal neurogenesis

2005 • 1,460 citations

Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

2006 • 1,273 citations

A Tumorigenic Subpopulation with Stem Cell Properties in Melanomas

2005 • 1,263 citations

Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours

2003 • 1,243 citations

Hedgehog Signaling and Bmi-1 Regulate Self-renewal of Normal and Malignant Human Mammary Stem Cells

2006 • 1,209 citations

Highly purified CD44+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells

2006 • 951 citations

Notch signalling regulates stem cell numbers in vitro and in vivo

2006 • 943 citations

Hedgehog signalling in cancer formation and maintenance

2003 • 821 citations

Characterization of clonogenic multiple myeloma cells

2003 • 783 citations

CD133, a novel marker for human prostatic epithelial stem cells

2004 • 773 citations

Ovarian cancer side population defines cells with stem cell-like characteristics and Mullerian Inhibiting Substance responsiveness

2006 • 747 citations

Normal Stem Cells and Cancer Stem Cells: The Niche Matters

2006 • 665 citations

Molecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer.

2003 • 540 citations

Ep-CAM: a human epithelial antigen is a homophilic cell-cell adhesion molecule.

1994 • 515 citations

Bmi1, stem cells, and senescence regulation

2004 • 442 citations

Preferential induction of apoptosis for primary human leukemic stem cells

2002 • 424 citations

Bmi1, stem cells, and senescence regulation

2004 • 411 citations

Allelotype of pancreatic adenocarcinoma using xenograft enrichment.

1995 • 308 citations

Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism

2006 • 285 citations

Human acute myeloid leukemia CD34+/CD38- progenitor cells have decreased sensitivity to chemotherapy and Fas-induced apoptosis, reduced immunogenicity, and impaired dendritic cell transformation capacities.

2000 • 281 citations

S100P Promotes Pancreatic Cancer Growth, Survival, and Invasion

2005 • 240 citations

Cytoplasmic CD24 Expression in Colorectal Cancer Independently Correlates with Shortened Patient Survival

2005 • 159 citations

Deaths: Final Data for 2003

2006 • 71 citations

Pten dependence distinguishes hematopoietic stem cells from leukemia-initiating cells

2006 • 15 citations