6,8-Difluoro-4-methylumbiliferyl phosphate: a fluorogenic substrate for protein tyrosine phosphatases

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

1985 • 2,257 citations

Increased Energy Expenditure, Decreased Adiposity, and Tissue-Specific Insulin Sensitivity in Protein-Tyrosine Phosphatase 1B-Deficient Mice

2000 • 1,218 citations

Mechanism of Inhibition of Protein-tyrosine Phosphatases by Vanadate and Pervanadate

1997 • 811 citations

THE STRUCTURE AND MECHANISM OF PROTEIN PHOSPHATASES: Insights into Catalysis and Regulation

1998 • 706 citations

Structural and Evolutionary Relationships among Protein Tyrosine Phosphatase Domains

2001 • 694 citations

Protein tyrosine phosphatase 1B inhibitors for diabetes

2002 • 629 citations

Protein tyrosine phosphatases: prospects for therapeutics

2001 • 344 citations

Structural basis for inhibition of receptor protein-tyrosine phosphatase-α by dimerization

1996 • 324 citations

Expression, purification, and physicochemical characterization of a recombinant Yersinia protein tyrosine phosphatase.

1992 • 228 citations

Synthesis of novel fluorinated coumarins: Excellent UV-light excitable fluorescent dyes

1998 • 192 citations

Fluorogenic Substrates Based on Fluorinated Umbelliferones for Continuous Assays of Phosphatases and β-Galactosidases

1999 • 175 citations

Mechanistic Studies on Protein Tyrosine Phosphatases

2003 • 118 citations

A Continuous Spectrophotometric and Fluorometric Assay for Protein Tyrosine Phosphatase Using Phosphotyrosine-Containing Peptides

1993 • 117 citations

Protein Tyrosine Phosphatases: Mechanism of Catalysis and Substrate Specificity

1994 • 88 citations

Purification and characterization of a human recombinant T-cell protein-tyrosine-phosphatase from a baculovirus expression system

1991 • 71 citations

Purification and characterization of a soluble catalytic fragment of the human transmembrane leukocyte antigen related (LAR) protein tyrosine phosphatase from an E. coli expression system

1991 • 67 citations

A Fluorescent Microplate Assay for Microcystin-LR

1999 • 55 citations

3,6-Fluorescein Diphosphate: A Sensitive Fluorogenic and Chromogenic Substrate for Protein Tyrosine Phosphatases

1999 • 54 citations

Protein tyrosine phosphatase 1B as a target for the treatment of impaired glucose tolerance and type II diabetes.

2002 • 34 citations

Fluorescein monophosphates as fluorogenic substrates for protein tyrosine phosphatases

1999 • 31 citations

Development of Fluorescence-Based Selective Assays for Serine / Threonine and Tyrosine Phosphatases

2003 • 20 citations

Expression, purification and crystallization of human phosphotyrosine phosphatase 1B

1994 • 18 citations

Expression, Purification, and Crystallization of the Catalytic Domain of Protein Tyrosine Phosphatase SHP-1

1997 • 17 citations

High level expression and purification of the enzymatically active cytoplasmic region of human CD45 phosphatase from yeast

1994 • 9 citations