The mammalian homolog of the Drosophila discs large tumor suppressor protein up-regulates expression of the ELR+ CXC chemokine Scyb5

Chemokines

2000 • 3,773 citations

QUANTITATIVE STUDIES OF THE GROWTH OF MOUSE EMBRYO CELLS IN CULTURE AND THEIR DEVELOPMENT INTO ESTABLISHED LINES

1963 • 2,742 citations

The rat brain postsynaptic density fraction contains a homolog of the drosophila discs-large tumor suppressor protein

1992 • 1,180 citations

Cooperative Regulation of Cell Polarity and Growth by Drosophila Tumor Suppressors

2000 • 908 citations

The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions

1991 • 902 citations

Mechanisms of B-cell lymphoma pathogenesis

2005 • 902 citations

Mechanism and role of PDZ domains in signaling complex assembly

2001 • 819 citations

Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein

1997 • 462 citations

Binding of APC to the Human Homolog of the Drosophila Discs Large Tumor Suppressor Protein

1996 • 430 citations

Dlg protein is required for junction structure, cell polarity, and proliferation control in Drosophila epithelia.

1996 • 422 citations

Cloning and characterization of hdlg: the human homologue of the Drosophila discs large tumor suppressor binds to protein 4.1.

1994 • 365 citations

The tumour-suppressor genes lgl and dlg regulate basal protein targeting in Drosophila neuroblasts

2000 • 332 citations

Role of cortical tumour-suppressor proteins in asymmetric division of Drosophila neuroblast

2000 • 326 citations

A Network of PDZ-Containing Proteins Regulates T Cell Polarity and Morphology during Migration and Immunological Synapse Formation

2005 • 255 citations

Signaling pathways are focused at specialized regions of the plasma membrane by scaffolding proteins of the MAGUK family

1999 • 212 citations

The APC-hDLG complex negatively regulates cell cycle progression from the G0/G1 to S phase

2000 • 184 citations

Craniofacial Dysmorphogenesis Including Cleft Palate in Mice with an Insertional Mutation in the discs large Gene

2001 • 140 citations

Tax oncoprotein of HTLV-1 binds to the human homologue of Drosophila discs large tumor suppressor protein, hDLG, and perturbs its function in cell growth control

1999 • 122 citations

Somatic Mutations and Altered Expression of the Candidate Tumor Suppressors CSNK1ε , DLG1 , and EDD/hHYD in Mammary Ductal Carcinoma

2004 • 119 citations

Requirement of PDZ-Containing Proteins for Cell Cycle Regulation and Differentiation in the Mouse Lens Epithelium

2003 • 114 citations

Induction of the chemokine receptor CXCR3 on TCR-stimulated T cells: dependence on the release from persistent TCR-triggering and requirement for IFN-γ stimulation

2002 • 103 citations

Discs large (Dlg1) complexes in lymphocyte activation

2004 • 97 citations

Changes in expression of the human homologue of the Drosophila discs large tumour suppressor protein in high-grade premalignant cervical neoplasias

2002 • 78 citations

Identification of kidney mesenchymal genes by a combination of microarray analysis and Sall1-GFP knockin mice

2004 • 65 citations

The SH3, HOOK and guanylate kinase‐like domains of hDLG are important for its cytoplasmic localization

2002 • 15 citations