Functional expression of rat thioredoxin reductase: selenocysteine insertion sequence element is essential for the active enzyme

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Glutathione peroxidase activity in selenium-deficient rat liver

1976 • 3,413 citations

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1

1998 • 2,360 citations

REDOX REGULATION OF CELLULAR ACTIVATION

1997 • 1,121 citations

[21] Thioredoxin and thioredoxin reductase

1995 • 932 citations

SELENOCYSTEINE

1996 • 788 citations

The structure of the mouse glutathione peroxidase gene: the selenocysteine in the active site is encoded by the ‘termination’ codon, TGA.

1986 • 666 citations

Recognition of UGA as a selenocysteine codon in Type I deiodinase requires sequences in the 3′ untranslated region

1991 • 642 citations

Rat liver thioredoxin and thioredoxin reductase: purification and characterization

1982 • 610 citations

A new selenoprotein from human lung adenocarcinoma cells: purification, properties, and thioredoxin reductase activity.

1996 • 540 citations

Human Placenta Thioredoxin Reductase

1998 • 519 citations

Selenocysteine, identified as the penultimate C-terminal residue in human T-cell thioredoxin reductase, corresponds to TGA in the human placental gene.

1996 • 471 citations

Knowing when not to stop: selenocysteine incorporation in eukaryotes

1996 • 433 citations

Functional characterization of the eukaryotic SECIS elements which direct selenocysteine insertion at UGA codons.

1993 • 429 citations

Rat and Calf Thioredoxin Reductase Are Homologous to Glutathione Reductase with a Carboxyl-terminal Elongation Containing a Conserved Catalytically Active Penultimate Selenocysteine Residue

1998 • 261 citations

The cDNA for rat selenoprotein P contains 10 TGA codons in the open reading frame

1991 • 238 citations

The mechanism of thioredoxin reductase from human placenta is similar to the mechanisms of lipoamide dehydrogenase and glutathione reductase and is distinct from the mechanism of thioredoxin reductase from Escherichia coli

1997 • 227 citations

Thioredoxin Reductase Activity Is Decreased by Selenium Deficiency

1997 • 220 citations

Cloning and sequencing of a human thioredoxin reductase

1995 • 211 citations

Purification, cDNA cloning, and expression of UDP-N-acetylglucosamine: beta-D-mannoside beta-1,4N-acetylglucosaminyltransferase III from rat kidney.

1992 • 190 citations

Cloning and Functional Characterization of Human Selenophosphate Synthetase, an Essential Component of Selenoprotein Synthesis

1995 • 187 citations

A New Human Selenium-containing Protein

1998 • 180 citations

Purification and properties of a recombinant sulfur analog of murine selenium‐glutathione peroxidase

1992 • 174 citations

Mechanisms of the regulation of thioredoxin reductase activity in cancer cells by the chemopreventive agent selenium.

1997 • 129 citations

Sequences in the 3'-untranslated region of the human cellular glutathione peroxidase gene are necessary and sufficient for selenocysteine incorporation at the UGA codon

1993 • 124 citations

Rat skeletal muscle selenoprotein W: cDNA clone and mRNA modulation by dietary selenium.

1995 • 120 citations

Purification of human thioredoxin reductase: Properties and characterization by absorption and circular dichroism spectroscopy

1993 • 96 citations

A thiol-specific antioxidant and sequence homology to various proteins of unknown function.

1994 • 75 citations

Identification and Molecular Cloning of a Human Selenocysteine Insertion Sequence-binding Protein

1998 • 57 citations

RNA-binding Proteins That Specifically Recognize the Selenocysteine Insertion Sequence of Human Cellular Glutathione Peroxidase mRNA

1995 • 56 citations

Heparin-binding properties of selenium-containing thioredoxin reductase from HeLa cells and human lung adenocarcinoma cells

1997 • 38 citations