Cardiovascular actions of CRH and urocortin: an update

Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor

1995 • 1,469 citations

Mice deficient for corticotropin-releasing hormone receptor-2 display anxiety-like behaviour and are hypersensitive to stress

2000 • 836 citations

Abnormal adaptations to stress and impaired cardiovascular function in mice lacking corticotropin-releasing hormone receptor-2

2000 • 591 citations

Appetite-Suppressing Effects of Urocortin, a CRF-Related Neuropeptide

1996 • 561 citations

Distribution of corticotropin-releasing factor receptor mRNA expression in the rat brain and pituitary.

1994 • 514 citations

Identification of a second corticotropin-releasing factor receptor gene and characterization of a cDNA expressed in heart.

1995 • 497 citations

CRF2 alpha and CRF2 beta receptor mRNAs are differentially distributed between the rat central nervous system and peripheral tissues.

1995 • 444 citations

Chemical and Biological Characterization of Corticotropin Releasing Factor

1983 • 375 citations

A sauvagine/corticotropin-releasing factor receptor expressed in heart and skeletal muscle.

1995 • 373 citations

Corticotropin releasing factor induction of leukocyte-derived immunoreactive ACTH and endorphins

1986 • 361 citations

Urocortin Expression in Rat Brain: Evidence Against a Pervasive Relationship of Urocortin-Containing Projections With Targets Bearing Type 2 CRF Receptors

1999 • 354 citations

Do Centrally Administered Neuropeptides Access Cognate Receptors?: An Analysis in the Central Corticotropin-Releasing Factor System

2000 • 342 citations

Effect of synthetic ovine corticotropin-releasing factor. Dose response of plasma adrenocorticotropin and cortisol.

1983 • 244 citations

Urocortin Protects against Ischemic and Reperfusion Injury via a MAPK-dependent Pathway

2000 • 236 citations

Identification of a novel murine receptor for corticotropin-releasing hormone expressed in the heart.

1995 • 218 citations

Cardiac inotropic actions of urocortin in conscious sheep

1997 • 172 citations

Functional corticotropin releasing factor receptors in the primate peripheral sympathetic nervous system

1986 • 169 citations

Expression and protective effects of urocortin in cardiac myocytes

1998 • 139 citations

Human placenta and fetal membranes express human urocortin mRNA and peptide.

1996 • 136 citations

CRF2 alpha and CRF2 beta receptor mRNAs are differentially distributed between the rat central nervous system and peripheral tissues

1995 • 135 citations

Urocortin Messenger Ribonucleic Acid: Tissue Distribution in the Rat and Regulation in Thymus by Lipopolysaccharide and Glucocorticoids1

1999 • 123 citations

Corticotropin-Releasing Factor (CRF) Family of Ligands and Their Receptors

1997 • 123 citations

Expression of the mouse corticotropin-releasing hormone gene in vivo and targeted inactivation in embryonic stem cells.

1994 • 115 citations

Identification of a novel murine receptor for corticotropin-releasing hormone expressed in the heart

1995 • 113 citations

Coronary vasodilation and positive inotropism by urocortin in the isolated rat heart

2001 • 83 citations

Central nervous system effects of corticotropin releasing factor in the dog

1983 • 82 citations

Urocortin, a corticotropin-releasing factor-related mammalian peptide, inhibits edema due to thermal injury in rats

1996 • 81 citations

Distribution and concentration of urocortin, and effect of adrenalectomy on its content in rat hypothalamus

1998 • 80 citations

Urocortin, a Newly Identified Corticotropin-Releasing Factor-Related Mammalian Peptide, Stimulates Atrial Natriuretic Peptide and Brain Natriuretic Peptide Secretions from Neonatal Rat Cardiomyocytes

1998 • 74 citations

Human placenta and fetal membranes express human urocortin mRNA and peptide

1996 • 72 citations

Differential Antagonist Activity ofα-Helical Corticotropin-Releasing Factor_9–41in Three Bioassay Systems^*

1991 • 67 citations

Amunine (Ovine CRF), Urotensin I and Sauvagine, Three Structurally-Related Peptides, Produce Selective Dilation of the Mesenteric Circulation

1982 • 66 citations

Corticotropin-releasing factor, sauvagine, and urotensin I: effects on blood flow

1985 • 64 citations

Corticotropin-releasing factor and angiotensin II: Comparison of CNS actions to influence neuroendocrine and cardiovascular function

1984 • 62 citations

Comparison of hCRF and oCRF effects on cardiovascular responses after central, peripheral, and in vitro application

1995 • 50 citations

Urocortin Messenger Ribonucleic Acid: Tissue Distribution in the Rat and Regulation in Thymus by Lipopolysaccharide and Glucocorticoids

1999 • 50 citations

Hemodynamic effects of corticotropin releasing hormone in the anesthetized cynomolgus monkey

1986 • 47 citations

Hypotensive effects of ovine and human corticotrophin-releasing factors in man

1987 • 45 citations

Corticotropin-releasing hormone receptor expression and functional coupling in neonatal cardiac myocytes and AT-1 cells.

1996 • 45 citations

Differentiated hemodynamic responses to central versus peripheral administration of corticotropin-releasing factor in conscious rats

1991 • 45 citations

Regional hemodynamic responses to central administration of corticotropin-releasing factor (CRF)

1988 • 44 citations

Urocortin Expression in Rat Brain: Evidence Against a Pervasive Relationship of Urocortin‐Containing Projections With Targets Bearing Type 2 CRF Receptors

1999 • 41 citations

ACTH-elicited sodium appetite in sheep

1980 • 33 citations

The inhibitory effect of hormones associated with stress on Na appetite of sheep

2000 • 30 citations

Effects of corticotropin-releasing factor on isolated rat heart activity

1993 • 26 citations

Corticotropin-releasing hormone receptor expression and functional coupling in neonatal cardiac myocytes and AT-1 cells

1996 • 21 citations

The effect of intracerebroventricular infusions of CRF, sauvagine, ACTH (1-24) and ACTH (4-10) on blood pressure in sheep.

1984 • 9 citations

The effects of naloxone on the cardiovascular and respiratory effects of centrally administered corticotrophin releasing factor in conscious rabbits

1991 • 8 citations

Effects of infusion of combinations of adrenocorticosteroids on systemic and regional haemodynamics in conscious sheep

1996 • 8 citations

Cardiac and Vascular Actions of Urocortin

1999 • 7 citations

Evidence Against a Central Pressor Mechanism for Adrenocortical Steroid Hypertension in Sheep

1996 • 3 citations

Coronary vasodilation and positive inotropism by urocortin in the isolated rat heart

1999 • 2 citations