Inhibition of microsome-mediated binding of aflatoxin B1 to DNA by glutathione S-transferase

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The Carbon Monoxide-binding Pigment of Liver Microsomes

1964 • 11,832 citations

A procedure for the isolation of deoxyribonucleic acid from micro-organisms

1961 • 11,554 citations

The Role of Glutathione and Glutathione S-Transferases in the Metabolism of Chemical Carcinogens and Other Electrophilic Agents

1979 • 1,179 citations

The Glutathione S ‐Transferases: A Group of Multifunctional Detoxification Proteins

1978 • 686 citations

Acute and chronic effects of aflatoxin on the liver of domestic and laboratory animals: a review.

1969 • 510 citations

Liver microsomal metabolism of aflatoxin B 1 to a reactive derivative toxic to Salmonella typhimurium TA 1530.

1972 • 415 citations

Separation and purification of multiple forms of microsomal cytochrome P-450. Activities of different forms of cytochrome P-450 towards several compounds of environmental interest.

1977 • 367 citations

2,3-Dihydro-2-(guan-7-yl)-3-hydroxy-aflatoxin B1, a major acid hydrolysis product of aflatoxin B1-DNA or -ribosomal RNA adducts formed in hepatic microsome-mediated reactions and in rat liver in vivo.

1977 • 260 citations

Aflatoxin B1-2,3-oxide as a probable intermediate in the covalent binding of aflatoxins B1 and B2 to rat liver DNA and ribosomal RNA in vivo.

1977 • 252 citations

Identification of the principal aflatoxin B1-DNA adduct formed in vivo in rat liver.

1978 • 246 citations

Aflatoxin B1-2,3-oxide: Evidence for its formation in rat liver in vivo and by human liver microsomes in vitro

1974 • 213 citations

The major metabolite of aflatoxin B1 in the rat is a glutathione conjugate

1978 • 193 citations

Ligandin, the glutathione S-transferases, and chemically induced hepatocarcinogenesis: a review.

1977 • 177 citations

2,3-Dihydro-2,3-dihydroxy-aflatoxin B1: An acid hydrolysis product of an RNA-aflatoxin B1 adduct formed by hamster and rat liver microsomes in vitro

1973 • 128 citations

The reactivity and carcinogenicity of aflatoxin B1-2,3-dichloride, a model for the putative 2,3-oxide metabolite of aflatoxin B1.

1975 • 117 citations

Microsome-dependent binding of aflatoxin B1 to DNA, RNA, polyribonucleotides and protein in vitro

1973 • 87 citations

Hepatotoxic Activity of Retrorsine, Senkirkine and Hydroxysenkirkine in Newborn Rats, and the Role of Epoxides in Carcinogenesis by Pyrrolizidine Alkaloids and Aflatoxins

1970 • 82 citations

Chemical evidence for the formation of a reactive aflatoxin B₁ metabolite, by hamster liver microsomes

1973 • 79 citations

Binding of [14C]aflatoxin B1 to cellular macromolecules in the rat and hamster

1975 • 64 citations

Hepatic microsomal mixed function oxygenase: Enzyme multiplicity for the metabolism of carcinogens to DNA-binding metabolites

1974 • 61 citations

Reduced nicotinamide adenine dinucleotide phosphate-dependent formation of 2,3-dihydro-2,3-dihydroxyaflatoxin B1 from aflatoxin B1 by hepatic microsomes.

1978 • 58 citations

Interaction of aflatoxins B1 and G1 with tissues of the rat.

1970 • 42 citations

Association and dissociation of the Ah locus with the metabolism of aflatoxin B1 by mouse liver. Co-segregation of aflatoxin B1 hydroxylase induction with aryl hydrocarbon (benzo(a)pyrene) hydroxylase induction.

1978 • 38 citations

Methylation of DNA in rat liver and intestine by dimethylnitrosamine and N-methylnitrosourea

1977 • 37 citations

Oxidative metabolism of aflatoxin B1: observations on the formation of epoxide-glytathione conjugate

1975 • 34 citations

The presence of antibodies to human dopamine-β-hydroxylase in commercially available antisera

1974 • 8 citations