The nucleus accumbens–possible site of antipsychotic action of neuroleptic drugs?

REGIONAL STUDIES OF CATECHOLAMINES IN THE RAT BRAIN‐I

1966 • 5,429 citations

Quantitative recording of rotational behavior in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system

1970 • 1,980 citations

Dopaminergic neurons: effect of antipsychotic drugs and amphetamine on single cell activity.

1973 • 1,272 citations

Muscarinic Cholinergic Binding in Rat Brain

1974 • 1,214 citations

Ascending Monoamine Neurons to the Telencephalon and Diencephalon

1966 • 1,205 citations

An Anatomy of Schizophrenia?

1973 • 721 citations

Amphetamine Psychosis: A "Model" Schizophrenia Mediated by Catecholamines

1973 • 590 citations

Antischizophrenic Drugs and Brain Cholinergic Receptors

1974 • 474 citations

Frontiers in Catecholamine Research

1976 • 451 citations

Effects of chlorpromazine, haloperidol and reserpine on the levels of phenolic acids in rabbit corpus striatum

1964 • 414 citations

Anti-muscarinic properties of neuroleptics and drug-induced Parkinsonism

1974 • 382 citations

Antiparkinsonian Drugs: Inhibition of Dopamine Uptake in the Corpus Striatum as a Possible Mechanism of Action

1969 • 348 citations

A note on the connections and development of the nucleus accumbens

1975 • 347 citations

DOPAMINE IN THE MESOLIMBIC SYSTEM OF THE RAT BRAIN: ENDOGENOUS LEVELS AND THE EFFECTS OF DRUGS ON THE UPTAKE MECHANISM AND STIMULATION OF ADENYLATE CYCLASE ACTIVITY

1974 • 342 citations

Antipsychotic drug actions: a clue to the neuropathology of schizophrenia?

1973 • 336 citations

Phenothiazine Treatment in Acute Schizophrenia

1964 • 321 citations

DOPAMINE IN THE BASAL GANGLIA: Its Role and Therapeutic Implications (Including the Clinical Use of L-DOPA)

1973 • 316 citations

PHENOTHIAZINE TREATMENT IN ACUTE SCHIZOPHRENIA; EFFECTIVENESS: THE NATIONAL INSTITUTE OF MENTAL HEALTH PSYCHOPHARMACOLOGY SERVICE CENTER COLLABORATIVE STUDY GROUP.

1964 • 303 citations

Effect of clozapine on the turnover of dopamine in the corpus striatum and in the limbic system

1973 • 296 citations

Role of Catecholamines in the Amphetamine Excitatory Response

1966 • 273 citations

The Action of Neuroleptic Drugs on Dopamine-Stimulated Adenosine Cyclic 3',5'-Monophosphate Production in Rat Neostriatum and Limbic Forebrain

1974 • 240 citations

Dopamine turnover in the corpus striatum and the limbic system after treatment with neuroleptic and anti-acetylcholine drugs

1972 • 235 citations

CENTRAL DOPAMINERGIC NEURONS: NEUROPHYSIOLOGICAL IDENTIFICATION AND RESPONSES TO DRUGS**This research was supported by NIMH Grant MH-17871, USPHS Research Scientist Development Award MH-14459 (to G. K. A.), and the State of Connecticut.

1973 • 230 citations

Effect of drugs used in psychoses on cerebral dopamine metabolism

1970 • 226 citations

Interaction between cholinergic and catecholaminergic neurones in rat brain

1972 • 208 citations

The effect of tropolone on the formation of 3,4‐dihydroxyphenylacetic acid and 4‐hydroxy‐3‐methoxyphenylacetic acid in the brain of the mouse

1969 • 201 citations

MODIFICATION BY DRUGS OF THE METABOLISM OF 3,4‐DIHYDROXYPHENYLETHYLAMINE, NORADRENALINE AND 5‐HYDROXYTRYPTAMINE IN THE BRAIN

1965 • 200 citations

CHARACTERIZATION OF A DOPAMINE‐SENSITIVE ADENYLATE CYCLASE IN THE RAT CAUDATE NUCLEUS

1975 • 199 citations

3,4‐Dihydroxyphenylacetic acid and 4‐hydroxy‐3‐methoxyphenylacetic acid in the mouse striatum: a reflection of intra‐ and extra‐neuronal metabolism of dopamine?

1971 • 183 citations

Special antagonism of amphetamine-induced abnormal behaviour

1965 • 156 citations

Effect of thioridazine, clozapine and other antipsychotics on the kinetic state of tyrosine hydroxylase and on the turnover rate of dopamine in striatum and nucleus accumbens.

1975 • 145 citations

An analysis of the learning deficit following hyoscine administration to man

1973 • 137 citations

Relation of contraversive turning to unilateral release of dopamine from the nigrostriatal pathway in rats

1971 • 116 citations

Regional differences in homovanillic acid concentrations after acute and chronic administration of antipsychotic drugs

1974 • 110 citations

On the significance of the increase in homovanillic acid (HVA) caused by antipsychotic drugs in corpus striatum and limbic forebrain

1975 • 73 citations

THERAPEUTIC REVERSAL WITH BENZTROPINE IN SCHIZOPHRENICS

1975 • 67 citations

Amphetamine Psychosis

1957 • 54 citations

Is there a catecholamine-serotonin interaction in the control of locomotor activity?

1975 • 51 citations

Pathophysiology of schizophrenia and the striatum.

1972 • 49 citations

Effects of oxotremorine and physostigmine on the turnover of dopamine in the corpus striatum and the limbic system

1974 • 47 citations

The coincidence of schizophrenia and Parkinsonism: some neurochemical implications

1976 • 46 citations

Extrapyramidal Side Effects and Therapeutic Response

1965 • 45 citations

Neuroleptics: relation between cataleptic and anti-turning actions, and role of the cholinergic system

1974 • 34 citations

Clinical evaluation of thioridazine and chlorpromazine in chronic schizophrenics.

1963 • 25 citations

Brain dopamine and behaviour

1974 • 23 citations