The influence of B-cell idiotypes on the repertoire of suppressor T cells

A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains

1984 • 1,262 citations

Sequence relationships between putative T-cell receptor polypeptides and immunoglobulins

1984 • 719 citations

In a radiation chimaera, host H–2 antigens determine immune responsiveness of donor cytotoxic cells

1977 • 534 citations

Induction of T and B cell immunity by anti‐idiotypic antibody

1975 • 448 citations

Shared idiotypic determinants on B and T lymphocytes reactive against the same antigenic determinants. I. Demonstration of similar or identical idiotypes on IgG molecules and T-cell receptors with specificity for the same alloantigens.

1975 • 347 citations

SUPPRESSION OF IMMUNOGLOBULIN CLASS SYNTHESIS IN MICE

1972 • 240 citations

Cytotoxic T cells learn specificity for self H–2 during differentiation in the thymus

1978 • 219 citations

Idiotypes as Variable Region Markers Analogies between Receptors on Phosphorylcholine-Specific T and B Lymphocytes

1977 • 170 citations

Antigen- and receptor-driven regulatory mechanisms. IV. Idiotype-bearing I-J+ suppressor T cell factors induce second-order suppressor T cells which express anti-idiotypic receptors.

1980 • 166 citations

Cellular basis of regulation of expression of idiotype. I. T-suppressor cells specific for MOPC 460 idiotype regulate the expression of cells secreting anti-TNP antibodies bearing 460 idiotype.

1979 • 162 citations

Shared idiotypic determinants on antibodies and T-cell-derived suppressor factor specific for the random terpolymer L-glutamic acid60-L-alanine30-L-tyrosine10.

1979 • 142 citations

Mechanisms of regulation of cell-mediated immunity. IV. Azobenzenearsonate-specific suppressor factor(s) bear cross-reactive idiotypic determinants the expression of which is linked to the heavy-chain allotype linkage group of genes.

1979 • 121 citations

Hapten-specific T-cell responses to 4-hydroxy-3-nitrophenyl acetyl. II. Demonstration of idiotypic determinants on suppressor T cells.

1979 • 117 citations

Population dynamics of T lymphocytes. Renewal rate and expansion in the peripheral lymphoid organs.

1983 • 113 citations

Genetic control of immunoregulatory circuits. Genes linked to the Ig locus govern communication between regulatory T-cell sets.

1979 • 97 citations

Lysozyme-induced T-suppressor cells and antibodies have a predominant idiotype

1979 • 64 citations

Chronic Giardia muris infection in anti-IgM-treated mice. I. Analysis of immunoglobulin and parasite-specific antibody in normal and immunoglobulin-deficient animals.

1985 • 62 citations

T and B cells that recognize the same antigen do not transcribe similar heavy chain variable region gene segments.

1983 • 54 citations

The Role of the Histocompatibility Gene Complex in Lymphocyte Differentiation

1977 • 46 citations

Similarity of Idiotypic Determinants of T‐ and B‐Lymphocyte Receptors for Alloantigens

1977 • 45 citations

Influence of Thymus Genotype on Acquisition of Responsiveness in Delayed‐type Hypersensitivity

1979 • 42 citations

T cell development in B cell-deficient mice. II. Serological characterization of suppressor T cell factors (TsF1) produced in normal mice and in mice treated chronically with rabbit anti-mouse IgM antibodies.

1985 • 37 citations

Genetic linkage of the cytolytic T lymphocyte repertoire and immunoglobulin heavy chain genes.

1982 • 37 citations

A search for messenger RNA molecules bearing immunoglobulin VH nucleotide sequences in T cells.

1982 • 27 citations

The abnormal function of T cells in chronically anti‐μ‐treated mice with no mature B lymphocytes

1984 • 23 citations

Investigations into the nature of Igh-V region-restricted T cell interactions by using antibodies to antigens on methylcholanthrene-induced sarcomas. I. Analysis of an Igh-V-restricted suppressor-inducer factor.

1985 • 4 citations

Regulation of Allotype-Linked NP<sup>b</sup> Idiotype by an Idiotype-Positive Soluble Factor Derived from a T Cell Hybridoma

1984 • 3 citations