Lack of MHC class I surface expression on neoplastic cells and poor activation of the secretory pathway of cytotoxic cells in oral squamous cell carcinomas

IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression.

1993 • 862 citations

Catalyzed reporter deposition, a novel method of signal amplification application to immunoassays

1989 • 765 citations

Molecular Mechanisms of Lymphocyte-Mediated Cytotoxicity and Their Role in Immunological Protection and Pathogenesis In Vivo

1996 • 614 citations

Monoclonal antibodies raised against denatured HLA-B locus heavy chains permit biochemical characterization of certain HLA-C locus products.

1986 • 547 citations

Co-stimulation in T cell responses

1997 • 430 citations

The Fas Counterattack In Vivo: Apoptotic Depletion of Tumor-Infiltrating Lymphocytes Associated with Fas Ligand Expression by Human Esophageal Carcinoma

1998 • 331 citations

Natural killer cell receptors

1995 • 314 citations

Lack of HLA class I antigen expression by cultured melanoma cells FO-1 due to a defect in B2m gene expression.

1991 • 304 citations

Inhibitory MHC class I receptors on NK cells and T cells

1996 • 288 citations

HLA-A- and HLA-B-specific monoclonal antibodies reactive with free heavy chains in Western blots, in formalin-fixed, paraffin-embedded tissue sections and in cryo-immuno-electron microscopy

1990 • 252 citations

Regulation of KIR expression in human T cells: a safety mechanism that may impair protective T-cell responses

1998 • 245 citations

p53 expression above the basal cell layer in oral mucosa is an early event of malignant transformation and has predictive value for developing oral squamous cell carcinoma

1998 • 199 citations

T-cell deficiency in patients with squamous cell cancer of the head and neck

1975 • 177 citations

Immune regulation: a critical link between NK cells and CTLs

1996 • 164 citations

Perforin dependence of natural killer cell‐mediated tumor control in vivo

1995 • 161 citations

Absent or low expression of the zeta chain in T cells at the tumor site correlates with poor survival in patients with oral carcinoma.

1998 • 147 citations

Lymphocyte granule-mediated apoptosis: matters of viral mimicry and deadly proteases

1998 • 144 citations

Beta 2-microglobulin gene mutations: a study of established colorectal cell lines and fresh tumors.

1994 • 143 citations

The beta2-microglobulin mRNA in human Daudi cells has a mutated initiation codon but is still inducible by interferon.

1983 • 120 citations

Production and characterization of monoclonal antibodies raised against recombinant human granzymes A and B and showing cross reactions with the natural proteins

1993 • 86 citations

SURFACE IgM SPECIFICITY ON CELLS DERIVED FROM A BURKITT'S LYMPHOMA

1967 • 82 citations

Comparison of immune derangements in patients with different malignancies

1980 • 69 citations

Characterization of a Murine Cytomegalovirus Class I Major Histocompatibility Complex (MHC) Homolog: Comparison to MHC Molecules and to the Human Cytomegalovirus MHC Homolog

1998 • 69 citations

Localization and identification of granzymes A and B-expressing cells in normal human lymphoid tissue and peripheral blood

1995 • 64 citations

Assessment of cytotoxic T-lymphocyte phenotype using the specific markers granzyme B and TIA-1 in cervical neoplastic lesions

1997 • 58 citations

Killing mechanisms of cytotoxic lymphocytes

1997 • 58 citations

Antitumor effects of cytolytic T lymphocytes (CTL) and natural killer (NK) cells in head and neck cancer.

1996 • 44 citations

IL-2-lnduced Cellular Events

1998 • 42 citations

Antigen Presentation By Class I Major Histocompatibility Complex Molecules: A Context for Thinking About HLA‐G

1995 • 37 citations

The expression of cell surface MHC class I heavy and light chain molecules in pre‐malignant and malignant lesions of the oral mucosa

1987 • 23 citations

The significance of differences in prognostic value of quantitative pathologic features in FIGO stage III and IV serous adenocarcinoma of the ovary between a group of Danish patients and other groups

1995 • 3 citations